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Protein

Superoxide dismutase [Mn/Fe]

Gene

sodA

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.By similarity

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.1 Publication

Cofactori

Mn2+By similarity, Fe2+By similarityNote: Binds 1 Mn2+ or Fe2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27Manganese or ironBy similarity1
Metal bindingi81Manganese or ironBy similarity1
Metal bindingi161Manganese or ironBy similarity1
Metal bindingi165Manganese or ironBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processStress response
LigandIron, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciSEPI176280:G1G05-1246-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn/Fe] (EC:1.15.1.1)
Gene namesi
Name:sodA
Ordered Locus Names:SE_1240
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000001411 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001600771 – 199Superoxide dismutase [Mn/Fe]Add BLAST199

Interactioni

Subunit structurei

Homodimer.1 Publication

Protein-protein interaction databases

STRINGi176280.SE1240

Structurei

3D structure databases

ProteinModelPortaliP0C0Q6
SMRiP0C0Q6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4 Bacteria
COG0605 LUCA
KOiK04564
OMAiKWGSFDK

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

P0C0Q6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFELPNLPY AYDALEPHID KQTMEIHHDK HHNTYVTKLN SAVEGTDLEA
60 70 80 90 100
KSIEEIVANL DSVPSNIQTA VRNNGGGHLN HSLFWELLSP NSEEKGEVVD
110 120 130 140 150
KIKEQWGSLD EFKKEFADKA AARFGSGWAW LVVNNGQLEI VTTPNQDNPI
160 170 180 190
TEGKTPILGL DVWEHAYYLK YQNKRPDYIN AFWNVVNWEK VNELYNATK
Length:199
Mass (Da):22,722
Last modified:November 22, 2005 - v1
Checksum:iE25419284F3378DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF410177 Genomic DNA Translation: AAL09677.1
AE015929 Genomic DNA Translation: AAO04839.1
RefSeqiNP_764795.1, NC_004461.1
WP_001831217.1, NC_004461.1

Genome annotation databases

EnsemblBacteriaiAAO04839; AAO04839; SE_1240
GeneIDi1057028
KEGGisep:SE1240
PATRICifig|176280.10.peg.1208

Similar proteinsi

Entry informationi

Entry nameiSODM_STAES
AccessioniPrimary (citable) accession number: P0C0Q6
Secondary accession number(s): P0C0Q5, Q93CF4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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