ID   APX6_ORYSJ              Reviewed;         309 AA.
AC   P0C0L1;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   16-JUN-2009, entry version 28.
DE   RecName: Full=Probable L-ascorbate peroxidase 6, chloroplastic;
DE            EC=1.11.1.11;
DE   AltName: Full=OsAPx06;
DE   Flags: Precursor;
GN   Name=APX6; OrderedLocusNames=Os12g0178100, LOC_Os12g07820;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Ehrhartoideae; Oryzeae; Oryza.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease
RT   resistance genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   MEDLINE=22752273; PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [3]
RP   NOMENCLATURE.
RX   PubMed=15599508; DOI=10.1007/s00239-004-2666-z;
RA   Teixeira F.K., Menezes-Benavente L., Margis R., Margis-Pinheiro M.;
RT   "Analysis of the molecular evolutionary history of the ascorbate
RT   peroxidase gene family: inferences from the rice genome.";
RL   J. Mol. Evol. 59:761-770(2004).
CC   -!- FUNCTION: Plays a key role in hydrogen peroxide removal (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: L-ascorbate + H(2)O(2) = dehydroascorbate + 2
CC       H(2)O.
CC   -!- COFACTOR: Binds 1 heme B (iron-protoporphyrin IX) group (By
CC       similarity).
CC   -!- COFACTOR: Binds 1 potassium or calcium ion per subunit (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma (Probable).
CC   -!- SIMILARITY: Belongs to the peroxidase family. Ascorbate peroxidase
CC       subfamily.
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DR   EMBL; AL732376; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK061107; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001066305.1; -.
DR   UniGene; Os.9266; -.
DR   SMR; P0C0L1; 36-309.
DR   GeneID; 4351663; -.
DR   KEGG; osa:4351663; -.
DR   Gramene; P0C0L1; -.
DR   GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0016688; F:L-ascorbate peroxidase activity; IEA:EC.
DR   GO; GO:0030955; F:potassium ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002207; Asc_perxdse.
DR   InterPro; IPR002016; Haem_peroxidase_pln/fun/bac.
DR   InterPro; IPR019794; Peroxidases_AS.
DR   InterPro; IPR019793; Peroxidases_heam-ligand_BS.
DR   Pfam; PF00141; peroxidase; 1.
DR   PRINTS; PR00459; ASPEROXIDASE.
DR   PRINTS; PR00458; PEROXIDASE.
DR   PROSITE; PS00435; PEROXIDASE_1; 1.
DR   PROSITE; PS00436; PEROXIDASE_2; FALSE_NEG.
DR   PROSITE; PS50873; PEROXIDASE_4; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Chloroplast; Heme; Hydrogen peroxide; Iron; Metal-binding;
KW   Oxidoreductase; Peroxidase; Plastid; Potassium; Transit peptide.
FT   TRANSIT       1     32       Chloroplast (Potential).
FT   CHAIN        33    309       Probable L-ascorbate peroxidase 6,
FT                                chloroplastic.
FT                                /FTId=PRO_0000042656.
FT   ACT_SITE     69     69       Proton acceptor (By similarity).
FT   METAL       198    198       Iron (heme axial ligand) (By similarity).
FT   METAL       199    199       Potassium or calcium (By similarity).
FT   METAL       231    231       Potassium or calcium (By similarity).
FT   METAL       238    238       Potassium or calcium (By similarity).
FT   SITE         65     65       Transition state stabilizer (By
FT                                similarity).
SQ   SEQUENCE   309 AA;  33502 MW;  DB5600BC16FC0984 CRC64;
     MAVVHRLLRR GLSAASPLPS LQELGRRPAS SSAAAAGDAA AELRGAREDV KQLLKSTSCH
     PILVRLGWHD AGTYDKNITE WPKCGGANGS LRFEIELKHA ANAGLVNALK LIQPIKDKHA
     GVTYADLFQL ASATAIEEAG GPKIPMIYGR VDVAAPEQCP PEGRLPAAGP PSPAEHLREV
     FYRMGLSDKE IVALSGAHTL GRSRPERSGW GKPETKYTKN GPGAPGGQSW TSQWLKFDNS
     YFKDIKERRD EDLLVLPTDA VLFEDSSFKI YAEKYAADQD AFFEDYAEAH AKLSNLGAKF
     DPPKGISLE
//