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Protein

Nascent polypeptide-associated complex protein

Gene

nac

Organism
Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Contacts the emerging nascent chain on the ribosome.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciMMAR79929:GH5J-633-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nascent polypeptide-associated complex proteinUniRule annotation
Gene namesi
Name:nacUniRule annotation
Ordered Locus Names:MTBMA_c06300
OrganismiMethanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
Taxonomic identifieri79929 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
Proteomesi
  • UP000000345 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 117117Nascent polypeptide-associated complex proteinPRO_0000135600Add
BLAST

Interactioni

Subunit structurei

Homodimer. Interacts with the ribosome. Binds ribosomal RNA.UniRule annotation1 Publication

Protein-protein interaction databases

STRINGi79929.MTBMA_c06300.

Structurei

Secondary structure

1
117
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi27 – 293Combined sources
Beta strandi34 – 385Combined sources
Beta strandi40 – 489Combined sources
Beta strandi50 – 567Combined sources
Beta strandi59 – 668Combined sources
Beta strandi68 – 769Combined sources
Helixi81 – 9111Combined sources
Helixi95 – 10410Combined sources
Turni105 – 1073Combined sources
Helixi109 – 1157Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TR8X-ray2.27A/B19-117[»]
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0C0K9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 7769NAC-A/BUniRule annotationAdd
BLAST
Domaini79 – 11739UBAUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the NAC-alpha family.UniRule annotation
Contains 1 NAC-A/B (NAC-alpha/beta) domain.UniRule annotation
Contains 1 UBA domain.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04061. Archaea.
COG1308. LUCA.
HOGENOMiHOG000225886.
KOiK03626.
OMAiPRKMKQM.

Family and domain databases

HAMAPiMF_00814. NAC_arch. 1 hit.
InterProiIPR005231. NAC_arc.
IPR002715. Nas_poly-pep-assoc_cplx_dom.
IPR009060. UBA-like.
[Graphical view]
PfamiPF01849. NAC. 1 hit.
[Graphical view]
SMARTiSM01407. NAC. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
TIGRFAMsiTIGR00264. TIGR00264. 1 hit.
PROSITEiPS51151. NAC_AB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C0K9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPGMGMNPK QLKQMQRAMK QMGMDMKDLR GVEEVVIKLK KKEIIIKNPR
60 70 80 90 100
VNVMDFMGQK TYQVTGKARE CDLEAEVKIP DDDIELVMNQ TGVSREEATR
110
ALQETGGDLA EAIMRLS
Length:117
Mass (Da):13,242
Last modified:November 30, 2010 - v2
Checksum:iEA09DB09F0E785D9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti41 – 411K → R no nucleotide entry (PubMed:15665334).Curated
Sequence conflicti50 – 501R → K no nucleotide entry (PubMed:15665334).Curated
Sequence conflicti55 – 551D → E no nucleotide entry (PubMed:15665334).Curated
Sequence conflicti71 – 722CD → RS no nucleotide entry (PubMed:15665334).Curated
Sequence conflicti77 – 782VK → ME no nucleotide entry (PubMed:15665334).Curated
Sequence conflicti81 – 811D → E no nucleotide entry (PubMed:15665334).Curated
Sequence conflicti93 – 931V → A no nucleotide entry (PubMed:15665334).Curated
Sequence conflicti97 – 971E → D no nucleotide entry (PubMed:15665334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001710 Genomic DNA. Translation: ADL58225.1.
RefSeqiWP_013295449.1. NC_014408.1.

Genome annotation databases

EnsemblBacteriaiADL58225; ADL58225; MTBMA_c06300.
GeneIDi9704338.
KEGGimmg:MTBMA_c06300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001710 Genomic DNA. Translation: ADL58225.1.
RefSeqiWP_013295449.1. NC_014408.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TR8X-ray2.27A/B19-117[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi79929.MTBMA_c06300.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADL58225; ADL58225; MTBMA_c06300.
GeneIDi9704338.
KEGGimmg:MTBMA_c06300.

Phylogenomic databases

eggNOGiarCOG04061. Archaea.
COG1308. LUCA.
HOGENOMiHOG000225886.
KOiK03626.
OMAiPRKMKQM.

Enzyme and pathway databases

BioCyciMMAR79929:GH5J-633-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0C0K9.

Family and domain databases

HAMAPiMF_00814. NAC_arch. 1 hit.
InterProiIPR005231. NAC_arc.
IPR002715. Nas_poly-pep-assoc_cplx_dom.
IPR009060. UBA-like.
[Graphical view]
PfamiPF01849. NAC. 1 hit.
[Graphical view]
SMARTiSM01407. NAC. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
TIGRFAMsiTIGR00264. TIGR00264. 1 hit.
PROSITEiPS51151. NAC_AB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNAC_METTM
AccessioniPrimary (citable) accession number: P0C0K9
Secondary accession number(s): D9PVH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: November 30, 2010
Last modified: September 7, 2016
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.