Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UTP--glucose-1-phosphate uridylyltransferase 1

Gene

hasC1

Organism
Streptococcus pyogenes serotype M1
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathwayi: nucleotide-sugar metabolism

This protein is involved in the pathway nucleotide-sugar metabolism, which is part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the pathway nucleotide-sugar metabolism and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00215

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase 1 (EC:2.7.7.9)
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase 1
UDP-glucose pyrophosphorylase 1
Short name:
UDPGP 1
Uridine diphosphoglucose pyrophosphorylase 1
Gene namesi
Name:hasC1
Synonyms:hasC
Ordered Locus Names:SPy_2202, M5005_Spy1853
OrganismiStreptococcus pyogenes serotype M1
Taxonomic identifieri301447 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000750 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002013681 – 304UTP--glucose-1-phosphate uridylyltransferase 1Add BLAST304

Proteomic databases

PaxDbiP0C0I9
PRIDEiP0C0I9

Interactioni

Protein-protein interaction databases

STRINGi160490.SPy_2202

Structurei

3D structure databases

ProteinModelPortaliP0C0I9
SMRiP0C0I9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 2 family.Curated

Phylogenomic databases

eggNOGiENOG4105C3Y Bacteria
COG1210 LUCA
HOGENOMiHOG000283477
KOiK00963
OMAiDECSFSY

Family and domain databases

CDDicd02541 UGPase_prokaryotic, 1 hit
Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR005771 GalU_uridylyltTrfase_bac/arc
IPR005835 NTP_transferase_dom
IPR029044 Nucleotide-diphossugar_trans
PANTHERiPTHR43197 PTHR43197, 1 hit
PfamiView protein in Pfam
PF00483 NTP_transferase, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit
TIGRFAMsiTIGR01099 galU, 1 hit

Sequencei

Sequence statusi: Complete.

P0C0I9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKVRKAIIP AAGLGTRFLP ATKALAKEML PIVDKPTIQF IVEEALKSGI
60 70 80 90 100
EEILVVTGKA KRSIEDHFDS NFELEYNLQA KGKNELLKLV DETTAINLHF
110 120 130 140 150
IRQSHPRGLG DAVLQAKAFV GNEPFVVMLG DDLMDITNAS AKPLTKQLME
160 170 180 190 200
DYDKTHASTI AVMKVPHEDV SSYGVIAPQG KAVKGLYSVD TFVEKPQPED
210 220 230 240 250
APSDLAIIGR YLLTPEIFGI LERQTPGAGN EVQLTDAIDT LNKTQRVFAR
260 270 280 290 300
EFKGNRYDVG DKFGFMKTSI DYALEHPQVK EDLKNYIIKL GKALEKSKVP

THSK
Length:304
Mass (Da):33,650
Last modified:September 13, 2005 - v1
Checksum:i48149D764B5E2BEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004092 Genomic DNA Translation: AAK34830.1
CP000017 Genomic DNA Translation: AAZ52471.1
RefSeqiNP_270109.1, NC_002737.2

Genome annotation databases

EnsemblBacteriaiAAK34830; AAK34830; SPy_2202
AAZ52471; AAZ52471; M5005_Spy1853
GeneIDi901878
KEGGispy:SPy_2202
spz:M5005_Spy1853
PATRICifig|160490.10.peg.1907

Similar proteinsi

Entry informationi

Entry nameiHASC1_STRP1
AccessioniPrimary (citable) accession number: P0C0I9
Secondary accession number(s): Q48W04, Q54713
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health