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P0C0A9 (SVIP_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Small VCP/p97-interacting protein
Gene names
Name:Svip
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length76 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Overexpression causes the formation of large vacuoles that seemed to be derived from the endoplasmic reticulum. Ref.1

Subunit structure

Interacts with VCP. Ref.1

Subcellular location

Smooth endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.

Tissue specificity

Ubiquitous.

Sequence similarities

Belongs to the SVIP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7676Small VCP/p97-interacting protein
PRO_0000072339

Sequences

Sequence LengthMass (Da)Tools
P0C0A9 [UniParc].

Last modified August 30, 2005. Version 1.
Checksum: 485974815DBFD4FC

FASTA768,248
        10         20         30         40         50         60 
MGLCFPCPAE SAPPSPSPEE KRAKLAEAAE RRQKEAASRG ILDIQSVEAK KKKKEQLEKQ 

        70 
METSGPPAGG LRWTVS 

« Hide

References

[1]"SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation."
Nagahama M., Suzuki M., Hamada Y., Hatsuzawa K., Tani K., Yamamoto A., Tagaya M.
Mol. Biol. Cell 14:262-273(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH VCP.
Tissue: Brain.

Cross-references

Sequence databases

RefSeqNP_001258013.1. NM_001271084.1.
UniGeneRn.77399.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000052878.

Proteomic databases

PaxDbP0C0A9.
PRIDEP0C0A9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID499157.
KEGGrno:499157.
UCSCRGD:1565432. rat.

Organism-specific databases

CTD258010.
RGD1565432. Svip.

Phylogenomic databases

eggNOGNOG70810.
HOGENOMHOG000122415.
HOVERGENHBG094009.
InParanoidP0C0A9.
KOK14014.
OrthoDBEOG7VQJHF.
PhylomeDBP0C0A9.

Gene expression databases

GenevestigatorP0C0A9.

Family and domain databases

ProtoNetSearch...

Other

NextBio702037.
PROP0C0A9.

Entry information

Entry nameSVIP_RAT
AccessionPrimary (citable) accession number: P0C0A9
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: August 30, 2005
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families