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P0C0A9

- SVIP_RAT

UniProt

P0C0A9 - SVIP_RAT

Protein

Small VCP/p97-interacting protein

Gene

Svip

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Overexpression causes the formation of large vacuoles that seemed to be derived from the endoplasmic reticulum.1 Publication

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Small VCP/p97-interacting protein
    Gene namesi
    Name:Svip
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Unplaced

    Organism-specific databases

    RGDi1565432. Svip.

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi membrane Source: UniProtKB-SubCell
    2. plasma membrane Source: UniProtKB-SubCell
    3. smooth endoplasmic reticulum membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Endoplasmic reticulum, Golgi apparatus, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7676Small VCP/p97-interacting proteinPRO_0000072339Add
    BLAST

    Proteomic databases

    PaxDbiP0C0A9.
    PRIDEiP0C0A9.

    Expressioni

    Tissue specificityi

    Ubiquitous.

    Gene expression databases

    GenevestigatoriP0C0A9.

    Interactioni

    Subunit structurei

    Interacts with VCP.1 Publication

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000052878.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SVIP family.Curated

    Phylogenomic databases

    eggNOGiNOG70810.
    HOGENOMiHOG000122415.
    HOVERGENiHBG094009.
    InParanoidiP0C0A9.
    KOiK14014.
    OrthoDBiEOG7VQJHF.
    PhylomeDBiP0C0A9.

    Sequencei

    Sequence statusi: Complete.

    P0C0A9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGLCFPCPAE SAPPSPSPEE KRAKLAEAAE RRQKEAASRG ILDIQSVEAK   50
    KKKKEQLEKQ METSGPPAGG LRWTVS 76
    Length:76
    Mass (Da):8,248
    Last modified:August 30, 2005 - v1
    Checksum:i485974815DBFD4FC
    GO

    Sequence databases

    RefSeqiNP_001258013.1. NM_001271084.1.
    UniGeneiRn.77399.

    Genome annotation databases

    GeneIDi499157.
    KEGGirno:499157.
    UCSCiRGD:1565432. rat.

    Cross-referencesi

    Sequence databases

    RefSeqi NP_001258013.1. NM_001271084.1.
    UniGenei Rn.77399.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000052878.

    Proteomic databases

    PaxDbi P0C0A9.
    PRIDEi P0C0A9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 499157.
    KEGGi rno:499157.
    UCSCi RGD:1565432. rat.

    Organism-specific databases

    CTDi 258010.
    RGDi 1565432. Svip.

    Phylogenomic databases

    eggNOGi NOG70810.
    HOGENOMi HOG000122415.
    HOVERGENi HBG094009.
    InParanoidi P0C0A9.
    KOi K14014.
    OrthoDBi EOG7VQJHF.
    PhylomeDBi P0C0A9.

    Miscellaneous databases

    NextBioi 702037.
    PROi P0C0A9.

    Gene expression databases

    Genevestigatori P0C0A9.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation."
      Nagahama M., Suzuki M., Hamada Y., Hatsuzawa K., Tani K., Yamamoto A., Tagaya M.
      Mol. Biol. Cell 14:262-273(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH VCP.
      Tissue: Brain.

    Entry informationi

    Entry nameiSVIP_RAT
    AccessioniPrimary (citable) accession number: P0C0A9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2005
    Last sequence update: August 30, 2005
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3