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P0C0A9

- SVIP_RAT

UniProt

P0C0A9 - SVIP_RAT

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Protein

Small VCP/p97-interacting protein

Gene
Svip
Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Overexpression causes the formation of large vacuoles that seemed to be derived from the endoplasmic reticulum.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Small VCP/p97-interacting protein
Gene namesi
Name:Svip
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Unplaced

Organism-specific databases

RGDi1565432. Svip.

Subcellular locationi

GO - Cellular componenti

  1. Golgi membrane Source: UniProtKB-SubCell
  2. plasma membrane Source: UniProtKB-SubCell
  3. smooth endoplasmic reticulum membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7676Small VCP/p97-interacting proteinPRO_0000072339Add
BLAST

Proteomic databases

PaxDbiP0C0A9.
PRIDEiP0C0A9.

Expressioni

Tissue specificityi

Ubiquitous.

Gene expression databases

GenevestigatoriP0C0A9.

Interactioni

Subunit structurei

Interacts with VCP.1 Publication

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000052878.

Family & Domainsi

Sequence similaritiesi

Belongs to the SVIP family.

Phylogenomic databases

eggNOGiNOG70810.
HOGENOMiHOG000122415.
HOVERGENiHBG094009.
InParanoidiP0C0A9.
KOiK14014.
OrthoDBiEOG7VQJHF.
PhylomeDBiP0C0A9.

Sequencei

Sequence statusi: Complete.

P0C0A9-1 [UniParc]FASTAAdd to Basket

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MGLCFPCPAE SAPPSPSPEE KRAKLAEAAE RRQKEAASRG ILDIQSVEAK   50
KKKKEQLEKQ METSGPPAGG LRWTVS 76
Length:76
Mass (Da):8,248
Last modified:August 30, 2005 - v1
Checksum:i485974815DBFD4FC
GO

Sequence databases

RefSeqiNP_001258013.1. NM_001271084.1.
UniGeneiRn.77399.

Genome annotation databases

GeneIDi499157.
KEGGirno:499157.
UCSCiRGD:1565432. rat.

Cross-referencesi

Sequence databases

RefSeqi NP_001258013.1. NM_001271084.1.
UniGenei Rn.77399.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000052878.

Proteomic databases

PaxDbi P0C0A9.
PRIDEi P0C0A9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 499157.
KEGGi rno:499157.
UCSCi RGD:1565432. rat.

Organism-specific databases

CTDi 258010.
RGDi 1565432. Svip.

Phylogenomic databases

eggNOGi NOG70810.
HOGENOMi HOG000122415.
HOVERGENi HBG094009.
InParanoidi P0C0A9.
KOi K14014.
OrthoDBi EOG7VQJHF.
PhylomeDBi P0C0A9.

Miscellaneous databases

NextBioi 702037.
PROi P0C0A9.

Gene expression databases

Genevestigatori P0C0A9.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation."
    Nagahama M., Suzuki M., Hamada Y., Hatsuzawa K., Tani K., Yamamoto A., Tagaya M.
    Mol. Biol. Cell 14:262-273(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH VCP.
    Tissue: Brain.

Entry informationi

Entry nameiSVIP_RAT
AccessioniPrimary (citable) accession number: P0C0A9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: August 30, 2005
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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