P0C088 (NLTP_ARTVU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Non-specific lipid-transfer protein Short name=LTP Alternative name(s): Pollen allergen Art v 3 Allergen=Art v 3
Organism	Artemisia vulgaris (Mugwort)
Taxonomic identifier	4220 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Asterales › Asteraceae › Asteroideae › Anthemideae › Artemisiinae › Artemisia

Protein attributes

Sequence length	37 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues By similarity.
Allergenic properties	Causes an allergic reaction in human.
Sequence similarities	Belongs to the plant LTP family.
Mass spectrometry	Molecular mass is 9736 Da from positions 1 - ?. Determined by MALDI. Ref.1

Ontologies

Keywords
Biological process	Transport
Disease	Allergen
Ligand	Lipid-binding
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	lipid transport Inferred from electronic annotation. Source: InterPro
Molecular_function	lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›37	›37	Non-specific lipid-transfer protein		PRO_0000153869
Experimental info
	Non-terminal residue	37	1

Sequences

	Sequence		Length	Mass (Da)
	P0C088 [UniParc]. Last modified August 16, 2005. Version 1. Checksum: 8F3B8B18EEC5A443	FASTA	37	3,757
	10 20 30 ALTCSDVSNK ISPCLSYLKQ GGEVPADCCA GVKGLND

References

[1]

"Lipid-transfer proteins as potential plant panallergens: cross-reactivity among proteins of Artemisia pollen, Castanea nut and Rosaceae fruits, with different IgE-binding capacities." Diaz-Perales A., Lombardero M., Sanchez-Monge R., Garcia-Selles F.J., Pernas M., Fernandez-Rivas M., Barber D., Salcedo G. Clin. Exp. Allergy 30:1403-1410(2000) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY. Tissue: Pollen.

Cross-references

3D structure databases
ProteinModelPortal	P0C088.
ModBase	Search...
Protein family/group databases
Allergome	3104. Art v 3.0101. 59. Art v 3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR016140. Bifunc_inhib/LTP/seed_store. IPR000528. Plant_LTP. [Graphical view]
PRINTS	PR00382. LIPIDTRNSFER.
SUPFAM	SSF47699. Bifunc_inhib/LTP/seed_store. 1 hit.
PROSITE	PS00597. PLANT_LTP. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NLTP_ARTVU

Accession

Primary (citable) accession number: P0C088

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	August 16, 2005
Last modified:	April 3, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program