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Protein

Non-specific lipid-transfer protein

Gene
N/A
Organism
Artemisia vulgaris (Mugwort)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).By similarity

GO - Molecular functioni

  1. lipid binding Source: UniProtKB-KW

GO - Biological processi

  1. lipid transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Lipid-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific lipid-transfer protein
Short name:
LTP
Alternative name(s):
Pollen allergen Art v 3
Allergen: Art v 3
OrganismiArtemisia vulgaris (Mugwort)
Taxonomic identifieri4220 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeAnthemideaeArtemisiinaeArtemisia

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3104. Art v 3.0101.
59. Art v 3.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›37›37Non-specific lipid-transfer proteinPRO_0000153869Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the plant LTP family.Curated

Family and domain databases

InterProiIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
[Graphical view]
PRINTSiPR00382. LIPIDTRNSFER.
SUPFAMiSSF47699. SSF47699. 1 hit.

Sequencei

Sequence statusi: Fragment.

P0C088-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
ALTCSDVSNK ISPCLSYLKQ GGEVPADCCA GVKGLND
Length:37
Mass (Da):3,757
Last modified:August 15, 2005 - v1
Checksum:i8F3B8B18EEC5A443
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei37 – 371

Mass spectrometryi

Molecular mass is 9736 Da from positions 1 - ?. Determined by MALDI. 1 Publication

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3104. Art v 3.0101.
59. Art v 3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
[Graphical view]
PRINTSiPR00382. LIPIDTRNSFER.
SUPFAMiSSF47699. SSF47699. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Lipid-transfer proteins as potential plant panallergens: cross-reactivity among proteins of Artemisia pollen, Castanea nut and Rosaceae fruits, with different IgE-binding capacities."
    Diaz-Perales A., Lombardero M., Sanchez-Monge R., Garcia-Selles F.J., Pernas M., Fernandez-Rivas M., Barber D., Salcedo G.
    Clin. Exp. Allergy 30:1403-1410(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY.
    Tissue: Pollen.

Entry informationi

Entry nameiNLTP_ARTVU
AccessioniPrimary (citable) accession number: P0C088
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 15, 2005
Last sequence update: August 15, 2005
Last modified: March 31, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.