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Protein

Protein sirB1

Gene

sirB1

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11251-MONOMER.
ECOL316407:JW1205-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein sirB1
Gene namesi
Name:sirB1
Synonyms:ychA
Ordered Locus Names:b1214, JW1205
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11251. sirB1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Protein sirB1PRO_0000202377Add
BLAST

Proteomic databases

PaxDbiP0AGM5.
PRIDEiP0AGM5.

Interactioni

Protein-protein interaction databases

BioGridi4260115. 13 interactions.
DIPiDIP-35939N.
IntActiP0AGM5. 5 interactions.
STRINGi511145.b1214.

Structurei

3D structure databases

ProteinModelPortaliP0AGM5.
SMRiP0AGM5. Positions 186-256.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0162 family.Curated

Phylogenomic databases

eggNOGiENOG41063JG. Bacteria.
COG2912. LUCA.
HOGENOMiHOG000281267.
InParanoidiP0AGM5.
OMAiDGEMWLI.
OrthoDBiEOG6P334F.
PhylomeDBiP0AGM5.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR032698. SirB1_N.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF13371. TPR_9. 1 hit.
PF13369. Transglut_core2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AGM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSLADFEFN KAPLCEGMIL ACEAIRRDFP SQDVYDELER LVSLAKEEIS
60 70 80 90 100
QLLPLEEQLE KLIALFYGDW GFKASRGVYR LSDALWLDQV LKNRQGSAVS
110 120 130 140 150
LGAVLLWVAN RLDLPLLPVI FPTQLILRIE CPDGEIWLIN PFNGESLSEH
160 170 180 190 200
MLDVWLKGNI SPSAELFYED LDEADNIEVI RKLLDTLKAS LMEENQMELA
210 220 230 240 250
LRTSEALLQF NPEDPYEIRD RGLIYAQLDC EHVALNDLSY FVEQCPEDPI
260
SEMIRAQINN IAHKHIVLH
Length:269
Mass (Da):30,841
Last modified:December 20, 2005 - v1
Checksum:iB7EEAC15FE3BD763
GO

Sequence cautioni

The sequence BAA05916.1 differs from that shown. Reason: Frameshift at position 97. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18555 Genomic DNA. Translation: AAC43440.1.
U00096 Genomic DNA. Translation: AAC74298.1.
AP009048 Genomic DNA. Translation: BAA36072.1.
D28567 Genomic DNA. Translation: BAA05916.1. Frameshift.
X05552 Genomic DNA. Translation: CAA29066.1.
PIRiI83572.
RefSeqiNP_415732.1. NC_000913.3.
WP_001257044.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74298; AAC74298; b1214.
BAA36072; BAA36072; BAA36072.
GeneIDi945784.
KEGGiecj:JW1205.
eco:b1214.
PATRICi32117680. VBIEscCol129921_1262.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18555 Genomic DNA. Translation: AAC43440.1.
U00096 Genomic DNA. Translation: AAC74298.1.
AP009048 Genomic DNA. Translation: BAA36072.1.
D28567 Genomic DNA. Translation: BAA05916.1. Frameshift.
X05552 Genomic DNA. Translation: CAA29066.1.
PIRiI83572.
RefSeqiNP_415732.1. NC_000913.3.
WP_001257044.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AGM5.
SMRiP0AGM5. Positions 186-256.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260115. 13 interactions.
DIPiDIP-35939N.
IntActiP0AGM5. 5 interactions.
STRINGi511145.b1214.

Proteomic databases

PaxDbiP0AGM5.
PRIDEiP0AGM5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74298; AAC74298; b1214.
BAA36072; BAA36072; BAA36072.
GeneIDi945784.
KEGGiecj:JW1205.
eco:b1214.
PATRICi32117680. VBIEscCol129921_1262.

Organism-specific databases

EchoBASEiEB1231.
EcoGeneiEG11251. sirB1.

Phylogenomic databases

eggNOGiENOG41063JG. Bacteria.
COG2912. LUCA.
HOGENOMiHOG000281267.
InParanoidiP0AGM5.
OMAiDGEMWLI.
OrthoDBiEOG6P334F.
PhylomeDBiP0AGM5.

Enzyme and pathway databases

BioCyciEcoCyc:EG11251-MONOMER.
ECOL316407:JW1205-MONOMER.

Miscellaneous databases

PROiP0AGM5.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR032698. SirB1_N.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF13371. TPR_9. 1 hit.
PF13369. Transglut_core2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Expression of genes kdsA and kdsB involved in 3-deoxy-D-manno-octulosonic acid metabolism and biosynthesis of enterobacterial lipopolysaccharide is growth phase regulated primarily at the transcriptional level in Escherichia coli K-12."
    Strohmaier H., Remler P., Renner W., Hoegenauer G.
    J. Bacteriol. 177:4488-4500(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Cloning and sequencing of a previously unidentified gene that is involved in the biosynthesis of heme in Escherichia coli."
    Nakayashiki T., Nishimura K., Inokuchi H.
    Gene 153:67-70(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-206.
    Strain: K12.
  6. "The kdsA gene coding for 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase is part of an operon in Escherichia coli."
    Woisetschlaeger M., Hoegenauer G.
    Mol. Gen. Genet. 207:369-373(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 124-269.

Entry informationi

Entry nameiSIRB1_ECOLI
AccessioniPrimary (citable) accession number: P0AGM5
Secondary accession number(s): P20101, P76020, Q9R325
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 20, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.