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Protein

UPF0126 inner membrane protein YicG

Gene

yicG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11683-MONOMER.
ECOL316407:JW3621-MONOMER.

Protein family/group databases

TCDBi1.A.62.2.3. the homotrimeric cation channel (tric) family.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0126 inner membrane protein YicG
Gene namesi
Name:yicG
Ordered Locus Names:b3646, JW3621
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11683. yicG.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2929CytoplasmicSequence analysisAdd
BLAST
Transmembranei30 – 5021HelicalSequence analysisAdd
BLAST
Topological domaini51 – 6414PeriplasmicSequence analysisAdd
BLAST
Transmembranei65 – 8521HelicalSequence analysisAdd
BLAST
Topological domaini86 – 872CytoplasmicSequence analysis
Transmembranei88 – 10821HelicalSequence analysisAdd
BLAST
Topological domaini109 – 1113PeriplasmicSequence analysis
Transmembranei112 – 13221HelicalSequence analysisAdd
BLAST
Topological domaini133 – 14715CytoplasmicSequence analysisAdd
BLAST
Transmembranei148 – 16821HelicalSequence analysisAdd
BLAST
Transmembranei169 – 18921HelicalSequence analysisAdd
BLAST
Topological domaini190 – 20516CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 205205UPF0126 inner membrane protein YicGPRO_0000166299Add
BLAST

Proteomic databases

PaxDbiP0AGM2.

Interactioni

Protein-protein interaction databases

BioGridi4262566. 4 interactions.
STRINGi511145.b3646.

Structurei

3D structure databases

ProteinModelPortaliP0AGM2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0126 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EN6. Bacteria.
COG2860. LUCA.
HOGENOMiHOG000218257.
InParanoidiP0AGM2.
OMAiLIAIRYR.
OrthoDBiEOG6WMJ34.
PhylomeDBiP0AGM2.

Family and domain databases

InterProiIPR005115. UPF0126.
[Graphical view]
PfamiPF03458. UPF0126. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AGM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLHILYLVG ITAEAMTGAL AAGRRRMDTF GVIIIATATA IGGGSVRDIL
60 70 80 90 100
LGHYPLGWVK HPEYVIIVAT AAVLTTIVAP VMPYLRKVFL VLDALGLVVF
110 120 130 140 150
SIIGAQVALD MGHGPIIAVV AAVTTGVFGG VLRDMFCKRI PLVFQKELYA
160 170 180 190 200
GVSFASAVLY IALQHYVSNH DVVIISTLVF GFFARLLALR LKLGLPVFYY

SHEGH
Length:205
Mass (Da):22,048
Last modified:December 20, 2005 - v1
Checksum:i346B73FB373F27C7
GO

Sequence cautioni

The sequence AAA61999.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA61999.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76670.2.
AP009048 Genomic DNA. Translation: BAE77647.1.
PIRiH65165.
RefSeqiNP_418103.4. NC_000913.3.
WP_000924289.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76670; AAC76670; b3646.
BAE77647; BAE77647; BAE77647.
GeneIDi948165.
KEGGiecj:JW3621.
eco:b3646.
PATRICi32122779. VBIEscCol129921_3766.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA61999.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76670.2.
AP009048 Genomic DNA. Translation: BAE77647.1.
PIRiH65165.
RefSeqiNP_418103.4. NC_000913.3.
WP_000924289.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AGM2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262566. 4 interactions.
STRINGi511145.b3646.

Protein family/group databases

TCDBi1.A.62.2.3. the homotrimeric cation channel (tric) family.

Proteomic databases

PaxDbiP0AGM2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76670; AAC76670; b3646.
BAE77647; BAE77647; BAE77647.
GeneIDi948165.
KEGGiecj:JW3621.
eco:b3646.
PATRICi32122779. VBIEscCol129921_3766.

Organism-specific databases

EchoBASEiEB1634.
EcoGeneiEG11683. yicG.

Phylogenomic databases

eggNOGiENOG4105EN6. Bacteria.
COG2860. LUCA.
HOGENOMiHOG000218257.
InParanoidiP0AGM2.
OMAiLIAIRYR.
OrthoDBiEOG6WMJ34.
PhylomeDBiP0AGM2.

Enzyme and pathway databases

BioCyciEcoCyc:EG11683-MONOMER.
ECOL316407:JW3621-MONOMER.

Miscellaneous databases

PROiP0AGM2.

Family and domain databases

InterProiIPR005115. UPF0126.
[Graphical view]
PfamiPF03458. UPF0126. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication."
    Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.
    Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYICG_ECOLI
AccessioniPrimary (citable) accession number: P0AGM2
Secondary accession number(s): P31432, P76720, Q2M7V9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 20, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.