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Protein

Xylose transport system permease protein XylH

Gene

xylH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:XYLH-MONOMER.
ECOL316407:JW3540-MONOMER.
MetaCyc:XYLH-MONOMER.

Protein family/group databases

TCDBi3.A.1.2.4. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose transport system permease protein XylH
Gene namesi
Name:xylH
Ordered Locus Names:b3568, JW3540
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12276. xylH.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24PeriplasmicSequence analysisAdd BLAST24
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 64CytoplasmicSequence analysisAdd BLAST19
Transmembranei65 – 85HelicalSequence analysisAdd BLAST21
Topological domaini86 – 102PeriplasmicSequence analysisAdd BLAST17
Transmembranei103 – 123HelicalSequence analysisAdd BLAST21
Topological domaini124 – 135CytoplasmicSequence analysisAdd BLAST12
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Topological domaini157 – 175PeriplasmicSequence analysisAdd BLAST19
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Topological domaini197 – 214CytoplasmicSequence analysisAdd BLAST18
Transmembranei215 – 235HelicalSequence analysisAdd BLAST21
Topological domaini236 – 239PeriplasmicSequence analysis4
Transmembranei240 – 260HelicalSequence analysisAdd BLAST21
Topological domaini261 – 287CytoplasmicSequence analysisAdd BLAST27
Transmembranei288 – 308HelicalSequence analysisAdd BLAST21
Topological domaini309 – 312PeriplasmicSequence analysis4
Transmembranei313 – 333HelicalSequence analysisAdd BLAST21
Topological domaini334 – 336CytoplasmicSequence analysis3
Transmembranei337 – 357HelicalSequence analysisAdd BLAST21
Topological domaini358 – 365PeriplasmicSequence analysis8
Transmembranei366 – 386HelicalSequence analysisAdd BLAST21
Topological domaini387 – 393CytoplasmicSequence analysis7

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602341 – 393Xylose transport system permease protein XylHAdd BLAST393

Proteomic databases

PaxDbiP0AGI4.
PRIDEiP0AGI4.

Interactioni

Protein-protein interaction databases

BioGridi4262543. 15 interactors.
IntActiP0AGI4. 3 interactors.
STRINGi511145.b3568.

Structurei

3D structure databases

ProteinModelPortaliP0AGI4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108HWW. Bacteria.
COG4214. LUCA.
HOGENOMiHOG000212233.
InParanoidiP0AGI4.
KOiK10544.
OMAiLREYGML.
PhylomeDBiP0AGI4.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AGI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKSNPSEVK LAVPTSGGFS GLKSLNLQVF VMIAAIIAIM LFFTWTTDGA
60 70 80 90 100
YLSARNVSNL LRQTAITGIL AVGMVFVIIS AEIDLSVGSM MGLLGGVAAI
110 120 130 140 150
CDVWLGWPLP LTIIVTLVLG LLLGAWNGWW VAYRKVPSFI VTLAGMLAFR
160 170 180 190 200
GILIGITNGT TVSPTSAAMS QIGQSYLPAS TGFIIGALGL MAFVGWQWRG
210 220 230 240 250
RMRRQALGLQ SPASTAVVGR QALTAIIVLG AIWLLNDYRG VPTPVLLLTL
260 270 280 290 300
LLLGGMFMAT RTAFGRRIYA IGGNLEAARL SGINVERTKL AVFAINGLMV
310 320 330 340 350
AIAGLILSSR LGAGSPSAGN IAELDAIAAC VIGGTSLAGG VGSVAGAVMG
360 370 380 390
AFIMASLDNG MSMMDVPTFW QYIVKGAILL LAVWMDSATK RRS
Length:393
Mass (Da):41,031
Last modified:December 20, 2005 - v1
Checksum:i2BE94243CEDC2C9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18545.1.
U00096 Genomic DNA. Translation: AAC76592.1.
AP009048 Genomic DNA. Translation: BAE77725.1.
PIRiS47789.
RefSeqiNP_418025.1. NC_000913.3.
WP_000045978.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76592; AAC76592; b3568.
BAE77725; BAE77725; BAE77725.
GeneIDi948083.
KEGGiecj:JW3540.
eco:b3568.
PATRICi32122612. VBIEscCol129921_3683.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18545.1.
U00096 Genomic DNA. Translation: AAC76592.1.
AP009048 Genomic DNA. Translation: BAE77725.1.
PIRiS47789.
RefSeqiNP_418025.1. NC_000913.3.
WP_000045978.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AGI4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262543. 15 interactors.
IntActiP0AGI4. 3 interactors.
STRINGi511145.b3568.

Protein family/group databases

TCDBi3.A.1.2.4. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP0AGI4.
PRIDEiP0AGI4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76592; AAC76592; b3568.
BAE77725; BAE77725; BAE77725.
GeneIDi948083.
KEGGiecj:JW3540.
eco:b3568.
PATRICi32122612. VBIEscCol129921_3683.

Organism-specific databases

EchoBASEiEB2185.
EcoGeneiEG12276. xylH.

Phylogenomic databases

eggNOGiENOG4108HWW. Bacteria.
COG4214. LUCA.
HOGENOMiHOG000212233.
InParanoidiP0AGI4.
KOiK10544.
OMAiLREYGML.
PhylomeDBiP0AGI4.

Enzyme and pathway databases

BioCyciEcoCyc:XYLH-MONOMER.
ECOL316407:JW3540-MONOMER.
MetaCyc:XYLH-MONOMER.

Miscellaneous databases

PROiP0AGI4.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiXYLH_ECOLI
AccessioniPrimary (citable) accession number: P0AGI4
Secondary accession number(s): P37389, Q2M7N1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.