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Protein

Xylose transport system permease protein XylH

Gene

xylH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:XYLH-MONOMER.
ECOL316407:JW3540-MONOMER.
MetaCyc:XYLH-MONOMER.
RETL1328306-WGS:GSTH-3214-MONOMER.

Protein family/group databases

TCDBi3.A.1.2.4. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose transport system permease protein XylH
Gene namesi
Name:xylH
Ordered Locus Names:b3568, JW3540
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12276. xylH.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2424PeriplasmicSequence analysisAdd
BLAST
Transmembranei25 – 4521HelicalSequence analysisAdd
BLAST
Topological domaini46 – 6419CytoplasmicSequence analysisAdd
BLAST
Transmembranei65 – 8521HelicalSequence analysisAdd
BLAST
Topological domaini86 – 10217PeriplasmicSequence analysisAdd
BLAST
Transmembranei103 – 12321HelicalSequence analysisAdd
BLAST
Topological domaini124 – 13512CytoplasmicSequence analysisAdd
BLAST
Transmembranei136 – 15621HelicalSequence analysisAdd
BLAST
Topological domaini157 – 17519PeriplasmicSequence analysisAdd
BLAST
Transmembranei176 – 19621HelicalSequence analysisAdd
BLAST
Topological domaini197 – 21418CytoplasmicSequence analysisAdd
BLAST
Transmembranei215 – 23521HelicalSequence analysisAdd
BLAST
Topological domaini236 – 2394PeriplasmicSequence analysis
Transmembranei240 – 26021HelicalSequence analysisAdd
BLAST
Topological domaini261 – 28727CytoplasmicSequence analysisAdd
BLAST
Transmembranei288 – 30821HelicalSequence analysisAdd
BLAST
Topological domaini309 – 3124PeriplasmicSequence analysis
Transmembranei313 – 33321HelicalSequence analysisAdd
BLAST
Topological domaini334 – 3363CytoplasmicSequence analysis
Transmembranei337 – 35721HelicalSequence analysisAdd
BLAST
Topological domaini358 – 3658PeriplasmicSequence analysis
Transmembranei366 – 38621HelicalSequence analysisAdd
BLAST
Topological domaini387 – 3937CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 393393Xylose transport system permease protein XylHPRO_0000060234Add
BLAST

Proteomic databases

PaxDbiP0AGI4.
PRIDEiP0AGI4.

Interactioni

Protein-protein interaction databases

BioGridi4262543. 15 interactions.
IntActiP0AGI4. 3 interactions.
STRINGi511145.b3568.

Structurei

3D structure databases

ProteinModelPortaliP0AGI4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108HWW. Bacteria.
COG4214. LUCA.
HOGENOMiHOG000212233.
InParanoidiP0AGI4.
KOiK10544.
OMAiLREYGML.
OrthoDBiEOG61P6T8.
PhylomeDBiP0AGI4.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AGI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKSNPSEVK LAVPTSGGFS GLKSLNLQVF VMIAAIIAIM LFFTWTTDGA
60 70 80 90 100
YLSARNVSNL LRQTAITGIL AVGMVFVIIS AEIDLSVGSM MGLLGGVAAI
110 120 130 140 150
CDVWLGWPLP LTIIVTLVLG LLLGAWNGWW VAYRKVPSFI VTLAGMLAFR
160 170 180 190 200
GILIGITNGT TVSPTSAAMS QIGQSYLPAS TGFIIGALGL MAFVGWQWRG
210 220 230 240 250
RMRRQALGLQ SPASTAVVGR QALTAIIVLG AIWLLNDYRG VPTPVLLLTL
260 270 280 290 300
LLLGGMFMAT RTAFGRRIYA IGGNLEAARL SGINVERTKL AVFAINGLMV
310 320 330 340 350
AIAGLILSSR LGAGSPSAGN IAELDAIAAC VIGGTSLAGG VGSVAGAVMG
360 370 380 390
AFIMASLDNG MSMMDVPTFW QYIVKGAILL LAVWMDSATK RRS
Length:393
Mass (Da):41,031
Last modified:December 20, 2005 - v1
Checksum:i2BE94243CEDC2C9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18545.1.
U00096 Genomic DNA. Translation: AAC76592.1.
AP009048 Genomic DNA. Translation: BAE77725.1.
PIRiS47789.
RefSeqiNP_418025.1. NC_000913.3.
WP_000045978.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76592; AAC76592; b3568.
BAE77725; BAE77725; BAE77725.
GeneIDi948083.
KEGGiecj:JW3540.
eco:b3568.
PATRICi32122612. VBIEscCol129921_3683.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18545.1.
U00096 Genomic DNA. Translation: AAC76592.1.
AP009048 Genomic DNA. Translation: BAE77725.1.
PIRiS47789.
RefSeqiNP_418025.1. NC_000913.3.
WP_000045978.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AGI4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262543. 15 interactions.
IntActiP0AGI4. 3 interactions.
STRINGi511145.b3568.

Protein family/group databases

TCDBi3.A.1.2.4. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP0AGI4.
PRIDEiP0AGI4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76592; AAC76592; b3568.
BAE77725; BAE77725; BAE77725.
GeneIDi948083.
KEGGiecj:JW3540.
eco:b3568.
PATRICi32122612. VBIEscCol129921_3683.

Organism-specific databases

EchoBASEiEB2185.
EcoGeneiEG12276. xylH.

Phylogenomic databases

eggNOGiENOG4108HWW. Bacteria.
COG4214. LUCA.
HOGENOMiHOG000212233.
InParanoidiP0AGI4.
KOiK10544.
OMAiLREYGML.
OrthoDBiEOG61P6T8.
PhylomeDBiP0AGI4.

Enzyme and pathway databases

BioCyciEcoCyc:XYLH-MONOMER.
ECOL316407:JW3540-MONOMER.
MetaCyc:XYLH-MONOMER.
RETL1328306-WGS:GSTH-3214-MONOMER.

Miscellaneous databases

PROiP0AGI4.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes."
    Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.
    Nucleic Acids Res. 22:2576-2586(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiXYLH_ECOLI
AccessioniPrimary (citable) accession number: P0AGI4
Secondary accession number(s): P37389, Q2M7N1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 20, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.