Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribose import permease protein RbsC

Gene

rbsC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane.2 Publications

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:RBSC-MONOMER.
ECOL316407:JW3729-MONOMER.
MetaCyc:RBSC-MONOMER.

Protein family/group databases

TCDBi3.A.1.2.1. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribose import permease protein RbsCCurated
Gene namesi
Name:rbsC1 Publication
Ordered Locus Names:b3750, JW3729
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10816. rbsC.

Subcellular locationi

  • Cell inner membrane 2 Publications; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 22Cytoplasmic1 PublicationAdd BLAST22
Transmembranei23 – 43Helical1 PublicationAdd BLAST21
Topological domaini44 – 56Periplasmic1 PublicationAdd BLAST13
Transmembranei57 – 77Helical1 PublicationAdd BLAST21
Topological domaini78 – 125Cytoplasmic1 PublicationAdd BLAST48
Transmembranei126 – 145Helical1 PublicationAdd BLAST20
Topological domaini146 – 168Periplasmic1 PublicationAdd BLAST23
Transmembranei169 – 190Helical1 PublicationAdd BLAST22
Topological domaini191 – 220Cytoplasmic1 PublicationAdd BLAST30
Transmembranei221 – 240Helical1 PublicationAdd BLAST20
Topological domaini241 – 294Periplasmic1 PublicationAdd BLAST54
Transmembranei295 – 316Helical1 PublicationAdd BLAST22
Topological domaini317 – 321Cytoplasmic2 Publications5

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602231 – 321Ribose import permease protein RbsCAdd BLAST321

Proteomic databases

PaxDbiP0AGI1.
PRIDEiP0AGI1.

Interactioni

Subunit structurei

The complex is composed of an ATP-binding protein (RbsA), two transmembrane proteins (RbsC) and a solute-binding protein (RbsB).1 Publication

Protein-protein interaction databases

BioGridi4263450. 20 interactors.
STRINGi511145.b3750.

Structurei

3D structure databases

ProteinModelPortaliP0AGI1.
SMRiP0AGI1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CNN. Bacteria.
COG1172. LUCA.
HOGENOMiHOG000212232.
InParanoidiP0AGI1.
KOiK10440.
OMAiLAVMIDN.
PhylomeDBiP0AGI1.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AGI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTQTVSGRR YFTKAWLMEQ KSLIALLVLI AIVSTLSPNF FTINNLFNIL
60 70 80 90 100
QQTSVNAIMA VGMTLVILTS GIDLSVGSLL ALTGAVAASI VGIEVNALVA
110 120 130 140 150
VAAALALGAA IGAVTGVIVA KGRVQAFIAT LVMMLLLRGV TMVYTNGSPV
160 170 180 190 200
NTGFTENADL FGWFGIGRPL GVPTPVWIMG IVFLAAWYML HHTRLGRYIY
210 220 230 240 250
ALGGNEAATR LSGINVNKIK IIVYSLCGLL ASLAGIIEVA RLSSAQPTAG
260 270 280 290 300
TGYELDAIAA VVLGGTSLAG GKGRIVGTLI GALILGFLNN GLNLLGVSSY
310 320
YQMIVKAVVI LLAVLVDNKK Q
Length:321
Mass (Da):33,452
Last modified:December 20, 2005 - v1
Checksum:iC7292EE5F0C78781
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti126A → P (PubMed:3011793).Curated1
Sequence conflicti202L → V in AAA51474 (PubMed:3011793).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M13169 Genomic DNA. Translation: AAA51474.1.
L10328 Genomic DNA. Translation: AAA62103.1.
U00096 Genomic DNA. Translation: AAC76773.1.
AP009048 Genomic DNA. Translation: BAE77538.1.
PIRiG65178.
RefSeqiNP_418206.1. NC_000913.3.
WP_000211858.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76773; AAC76773; b3750.
BAE77538; BAE77538; BAE77538.
GeneIDi948262.
KEGGiecj:JW3729.
eco:b3750.
PATRICi32122999. VBIEscCol129921_3875.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M13169 Genomic DNA. Translation: AAA51474.1.
L10328 Genomic DNA. Translation: AAA62103.1.
U00096 Genomic DNA. Translation: AAC76773.1.
AP009048 Genomic DNA. Translation: BAE77538.1.
PIRiG65178.
RefSeqiNP_418206.1. NC_000913.3.
WP_000211858.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AGI1.
SMRiP0AGI1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263450. 20 interactors.
STRINGi511145.b3750.

Protein family/group databases

TCDBi3.A.1.2.1. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP0AGI1.
PRIDEiP0AGI1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76773; AAC76773; b3750.
BAE77538; BAE77538; BAE77538.
GeneIDi948262.
KEGGiecj:JW3729.
eco:b3750.
PATRICi32122999. VBIEscCol129921_3875.

Organism-specific databases

EchoBASEiEB0809.
EcoGeneiEG10816. rbsC.

Phylogenomic databases

eggNOGiENOG4105CNN. Bacteria.
COG1172. LUCA.
HOGENOMiHOG000212232.
InParanoidiP0AGI1.
KOiK10440.
OMAiLAVMIDN.
PhylomeDBiP0AGI1.

Enzyme and pathway databases

BioCyciEcoCyc:RBSC-MONOMER.
ECOL316407:JW3729-MONOMER.
MetaCyc:RBSC-MONOMER.

Miscellaneous databases

PROiP0AGI1.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRBSC_ECOLI
AccessioniPrimary (citable) accession number: P0AGI1
Secondary accession number(s): P04984, Q2M868
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: December 20, 2005
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.