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Protein

Phosphate transport system permease protein PstC

Gene

pstC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

  • phosphate ion transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:PSTC-MONOMER.
ECOL316407:JW3705-MONOMER.
MetaCyc:PSTC-MONOMER.

Protein family/group databases

TCDBi3.A.1.7.1. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate transport system permease protein PstC
Gene namesi
Name:pstC
Synonyms:phoW
Ordered Locus Names:b3727, JW3705
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10784. pstC.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
Transmembranei25 – 44HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini45 – 74PeriplasmicSequence analysisAdd BLAST30
Transmembranei75 – 94HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini95 – 117CytoplasmicSequence analysisAdd BLAST23
Transmembranei118 – 137HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini138 – 167PeriplasmicSequence analysisAdd BLAST30
Transmembranei168 – 187HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini188 – 232CytoplasmicSequence analysisAdd BLAST45
Transmembranei233 – 252HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini253 – 283PeriplasmicSequence analysisAdd BLAST31
Transmembranei284 – 303HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini304 – 319CytoplasmicSequence analysisAdd BLAST16

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602071 – 319Phosphate transport system permease protein PstCAdd BLAST319

Proteomic databases

PaxDbiP0AGH8.
PRIDEiP0AGH8.

Interactioni

Protein-protein interaction databases

BioGridi4262140. 22 interactors.
STRINGi511145.b3727.

Structurei

3D structure databases

ProteinModelPortaliP0AGH8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 305ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST231

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C8U. Bacteria.
COG0573. LUCA.
HOGENOMiHOG000074139.
InParanoidiP0AGH8.
KOiK02037.
OMAiKESAYGV.
PhylomeDBiP0AGH8.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
IPR011864. Phosphate_PstC.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR02138. phosphate_pstC. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AGH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATKPAFNP PGKKGDIIFS VLVKLAALIV LLMLGGIIVS LIISSWPSIQ
60 70 80 90 100
KFGLAFLWTK EWDAPNDIYG ALVPIYGTLV TSFIALLIAV PVSFGIALFL
110 120 130 140 150
TELAPGWLKR PLGIAIELLA AIPSIVYGMW GLFIFAPLFA VYFQEPVGNI
160 170 180 190 200
MSNIPIVGAL FSGPAFGIGI LAAGVILAIM IIPYIAAVMR DVFEQTPVMM
210 220 230 240 250
KESAYGIGCT TWEVIWRIVL PFTKNGVIGG IMLGLGRALG ETMAVTFIIG
260 270 280 290 300
NTYQLDSASL YMPGNSITSA LANEFAEAES GLHVAALMEL GLILFVITFI
310
VLAASKFMIM RLAKNEGAR
Length:319
Mass (Da):34,121
Last modified:April 1, 1988 - v1
Checksum:i843F9E811DB62597
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02723 Genomic DNA. Translation: CAA26507.1.
K01992 Genomic DNA. Translation: AAA24379.1.
L10328 Genomic DNA. Translation: AAA62078.1.
U00096 Genomic DNA. Translation: AAC76750.1.
AP009048 Genomic DNA. Translation: BAE77561.1.
PIRiH65175. BVECPW.
RefSeqiNP_418183.1. NC_000913.3.
WP_000741620.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76750; AAC76750; b3727.
BAE77561; BAE77561; BAE77561.
GeneIDi948238.
KEGGiecj:JW3705.
eco:b3727.
PATRICi32122951. VBIEscCol129921_3851.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02723 Genomic DNA. Translation: CAA26507.1.
K01992 Genomic DNA. Translation: AAA24379.1.
L10328 Genomic DNA. Translation: AAA62078.1.
U00096 Genomic DNA. Translation: AAC76750.1.
AP009048 Genomic DNA. Translation: BAE77561.1.
PIRiH65175. BVECPW.
RefSeqiNP_418183.1. NC_000913.3.
WP_000741620.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AGH8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262140. 22 interactors.
STRINGi511145.b3727.

Protein family/group databases

TCDBi3.A.1.7.1. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP0AGH8.
PRIDEiP0AGH8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76750; AAC76750; b3727.
BAE77561; BAE77561; BAE77561.
GeneIDi948238.
KEGGiecj:JW3705.
eco:b3727.
PATRICi32122951. VBIEscCol129921_3851.

Organism-specific databases

EchoBASEiEB0777.
EcoGeneiEG10784. pstC.

Phylogenomic databases

eggNOGiENOG4105C8U. Bacteria.
COG0573. LUCA.
HOGENOMiHOG000074139.
InParanoidiP0AGH8.
KOiK02037.
OMAiKESAYGV.
PhylomeDBiP0AGH8.

Enzyme and pathway databases

BioCyciEcoCyc:PSTC-MONOMER.
ECOL316407:JW3705-MONOMER.
MetaCyc:PSTC-MONOMER.

Miscellaneous databases

PROiP0AGH8.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
IPR011864. Phosphate_PstC.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR02138. phosphate_pstC. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPSTC_ECOLI
AccessioniPrimary (citable) accession number: P0AGH8
Secondary accession number(s): P07653, Q2M845
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: November 30, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.