P0AGG6 (THIO2_ECO57) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 48.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Thioredoxin-2 Short name=Trx-2 EC=1.8.1.8 Alternative name(s): Protein-disulfide reductase | ||||
| Gene names |
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| Organism | Escherichia coli O157:H7 [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 83334 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 139 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Efficient electron donor for the essential enzyme ribonucleotide reductase. Is also able to reduce the interchain disulfide bridges of insulin By similarity. |
| Catalytic activity | Protein dithiol + NAD(P)+ = protein disulfide + NAD(P)H. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the thioredoxin family. Contains 1 thioredoxin domain. |
Ontologies
Sequence annotation (Features)
Sequences
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References
Cross-references
Sequence databases | |
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| EMBL GenBank DDBJ | AE005174 Genomic DNA. Translation: AAG57699.1. BA000007 Genomic DNA. Translation: BAB36871.1. |
| PIR | G85904. H91059. |
| RefSeq | NP_289141.1. NC_002655.2. NP_311475.1. NC_002695.1. |
3D structure databases | |
| ProteinModelPortal | P0AGG6. |
| SMR | P0AGG6. Positions 36-139. |
| ModBase | Search... |
Protein-protein interaction databases | |
| MINT | MINT-1227488. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBESCT00000025685; EBESCP00000024578; EBESCG00000024738. EBESCT00000056440; EBESCP00000054268; EBESCG00000055488. |
| GeneID | 914878. 957981. |
| GenomeReviews | Gene locus Z3867 in contig AE005174_GR. Gene locus ECs3448 in contig BA000007_GR. |
| KEGG | ece:Z3867. ecs:ECs3448. |
| PATRIC | 18356334. VBIEscCol44059_3362. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000008978. |
| HOGENOM | HBG493509. |
| OMA | MIFKQGH. |
| ProtClustDB | PRK10996. |
Enzyme and pathway databases | |
| BioCyc | ECOL83334:ECS3448-MONOMER. |
Family and domain databases | |
| InterPro | IPR005746. Thioredoxin. IPR012336. Thioredoxin-like_fold. IPR017937. Thioredoxin_CS. IPR013766. Thioredoxin_domain. [Graphical view] |
| Gene3D | G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. |
| KO | K03672. |
| PANTHER | PTHR10438. Trx. 1 hit. |
| Pfam | PF00085. Thioredoxin. 1 hit. [Graphical view] |
| PIRSF | PIRSF000077. Thioredoxin. 1 hit. |
| PRINTS | PR00421. THIOREDOXIN. |
| SUPFAM | SSF52833. Thiordxn-like_fd. 1 hit. |
| TIGRFAMs | TIGR01068. Thioredoxin. 1 hit. |
| PROSITE | PS00194. THIOREDOXIN_1. 1 hit. PS51352. THIOREDOXIN_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | THIO2_ECO57 | ||||||||
| Accession | Primary (citable) accession number: P0AGG6 Secondary accession number(s): P33636 P77001 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with