Reviewed, UniProtKB/Swiss-Prot P0AGF2 (YGDK_ECOLI)

Names and origin

Protein names

Recommended name:
    Uncharacterized sufE-like protein ygdK

Gene names

Name:	ygdK
Ordered Locus Names:	b2811, JW2782

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the sufE family.

Ontologies

Keywords
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
nadE	P18843	1	EBI-1130454,EBI-548960

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 147

147

Uncharacterized sufE-like protein ygdK

PRO_0000202136

Secondary structure

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147

Helix Strand Turn

Details...

Beta strand

13 – 15

3

Helix

17 – 24

8

Helix

30 – 43

14

Helix

49 – 54

6

Beta strand

55 – 58

4

Beta strand

60 – 63

4

Beta strand

65 – 68

4

Beta strand

73 – 75

3

Beta strand

80 – 85

6

Helix

86 – 98

13

Turn

99 – 101

3

Helix

104 – 109

6

Helix

113 – 119

7

Beta strand

121 – 125

5

Sequences

	Sequence		Length	Mass (Da)
	P0AGF2-1 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: EECAB64427D42C41	FASTA	147	15,940
	10 20 30 40 50 60 MTNPQFAGHP FGTTVTAETL RNTFAPLTQW EDKYRQLIML GKQLPALPDE LKAQAKEIAG 70 80 90 100 110 120 CENRVWLGYT VAENGKMHFF GDSEGRIVRG LLAVLLTAVE GKTAAELQAQ SPLALFDELG 130 140 LRAQLSASRS QGLNALSEAI IAATKQV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]	"High-quality homology models derived from NMR and X-ray structures of E. coli proteins YgdK and SufE suggest that all members of the YgdK/SufE protein family are enhancers of cysteine desulfurases." Liu G., Li Z., Chiang Y., Acton T., Montelione G.T., Murray D., Szyperski T. Protein Sci. 14:1597-1608(2005) [PubMed: 15930006] [Abstract] Cited for: STRUCTURE BY NMR.

Cross-references

Sequence databases

EMBLGenBankDDBJ

U29581 Genomic DNA. Translation: AAB40461.1.
U00096 Genomic DNA. Translation: AAC75853.1.
AP009048 Genomic DNA. Translation: BAE76883.1.

PIR

G65063.

RefSeq

AP_003377.1.
NP_417291.1.

3D structure databases

PDBMSD

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1NI7	NMR	-	A	1-147	[»]

ModBase

Search...

Protein-protein interaction databases

IntAct

P0AGF2.

Genome annotation databases

GeneID

947274.

GenomeReviews

Gene locus b2811 in contig U00096_GR.
Gene locus JW2782 in contig AP009048_GR.

KEGG

ecj:JW2782.
eco:b2811.

Organism-specific databases

EchoBASE

EB2892.

EcoGene

EG13083. ygdK.

CMR

Search...

Phylogenomic databases

HOGENOM

P0AGF2.

Enzyme and pathway databases

BioCyc

EcoCyc:G7455-MON.
MetaCyc:G7455-MON.

Family and domain databases

InterPro

IPR017763. Cysteine_desulphurase_CsdE.
IPR003808. SufE.
[Graphical view]

Pfam

PF02657. SufE. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

YGDK_ECOLI

Accession

Primary (citable) accession number: P0AGF2
Secondary accession number(s): Q2MA23, Q46926

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	September 2, 2008
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)