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Protein

Single-stranded DNA-binding protein

Gene

ssb

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi55 – 61UniRule annotation7

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair, DNA replication

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciECOO157:SSB-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Single-stranded DNA-binding proteinUniRule annotation
Short name:
SSBUniRule annotation
Gene namesi
Name:ssb
Ordered Locus Names:Z5658, ECs5041
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000960372 – 178Single-stranded DNA-binding proteinAdd BLAST177

Proteomic databases

PRIDEiP0AGE2.

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

MINTiMINT-194657.
STRINGi155864.Z5658.

Structurei

3D structure databases

DisProtiDP00722.
ProteinModelPortaliP0AGE2.
SMRiP0AGE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 111SSBUniRule annotationAdd BLAST106

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi173 – 178Important for interaction with partner proteinsUniRule annotation6

Sequence similaritiesi

Contains 1 SSB domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UUM. Bacteria.
COG0629. LUCA.
HOGENOMiHOG000106483.
KOiK03111.
OMAiQQYNEPP.

Family and domain databases

HAMAPiMF_00984. SSB. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR000424. Primosome_PriB/ssb.
IPR011344. ssDNA-bd.
[Graphical view]
PANTHERiPTHR10302. PTHR10302. 1 hit.
PfamiPF00436. SSB. 1 hit.
[Graphical view]
PIRSFiPIRSF002070. SSB. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00621. ssb. 1 hit.
PROSITEiPS50935. SSB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AGE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASRGVNKVI LVGNLGQDPE VRYMPNGGAV ANITLATSES WRDKATGEMK
60 70 80 90 100
EQTEWHRVVL FGKLAEVASE YLRKGSQVYI EGQLRTRKWT DQSGQDRYTT
110 120 130 140 150
EVVVNVGGTM QMLGGRQGGG APAGGNIGGG QPQGGWGQPQ QPQGGNQFSG
160 170
GAQSRPQQSA PAAPSNEPPM DFDDDIPF
Length:178
Mass (Da):18,975
Last modified:January 23, 2007 - v2
Checksum:iF0AF43B6DC8D02FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG59257.1.
BA000007 Genomic DNA. Translation: BAB38464.1.
PIRiA91259.
RefSeqiNP_313068.1. NC_002695.1.
WP_000168305.1. NZ_LPWC02000002.1.

Genome annotation databases

EnsemblBacteriaiAAG59257; AAG59257; Z5658.
BAB38464; BAB38464; BAB38464.
GeneIDi914294.
KEGGiece:Z5658.
ecs:ECs5041.
PATRICi18359677. VBIEscCol44059_4975.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG59257.1.
BA000007 Genomic DNA. Translation: BAB38464.1.
PIRiA91259.
RefSeqiNP_313068.1. NC_002695.1.
WP_000168305.1. NZ_LPWC02000002.1.

3D structure databases

DisProtiDP00722.
ProteinModelPortaliP0AGE2.
SMRiP0AGE2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-194657.
STRINGi155864.Z5658.

Proteomic databases

PRIDEiP0AGE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG59257; AAG59257; Z5658.
BAB38464; BAB38464; BAB38464.
GeneIDi914294.
KEGGiece:Z5658.
ecs:ECs5041.
PATRICi18359677. VBIEscCol44059_4975.

Phylogenomic databases

eggNOGiENOG4108UUM. Bacteria.
COG0629. LUCA.
HOGENOMiHOG000106483.
KOiK03111.
OMAiQQYNEPP.

Enzyme and pathway databases

BioCyciECOO157:SSB-MONOMER.

Family and domain databases

HAMAPiMF_00984. SSB. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR000424. Primosome_PriB/ssb.
IPR011344. ssDNA-bd.
[Graphical view]
PANTHERiPTHR10302. PTHR10302. 1 hit.
PfamiPF00436. SSB. 1 hit.
[Graphical view]
PIRSFiPIRSF002070. SSB. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00621. ssb. 1 hit.
PROSITEiPS50935. SSB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSSB_ECO57
AccessioniPrimary (citable) accession number: P0AGE2
Secondary accession number(s): P02339
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.