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Protein

Protein Smp

Gene

smp

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG10951-MONOMER.
ECOL316407:JW4350-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Smp
Gene namesi
Name:smp
Synonyms:ytjB
Ordered Locus Names:b4387, JW4350
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10951. smp.

Subcellular locationi

  • Cell membrane 1 Publication; Single-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

No visible phenotype.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_000003280231 – 214Protein SmpAdd BLAST184

Post-translational modificationi

The signal sequence may not be cleaved.

Proteomic databases

PaxDbiP0AGC7.
PRIDEiP0AGC7.

Interactioni

Protein-protein interaction databases

BioGridi4262788. 13 interactors.
DIPiDIP-35920N.
IntActiP0AGC7. 6 interactors.
STRINGi511145.b4387.

Structurei

3D structure databases

ProteinModelPortaliP0AGC7.
SMRiP0AGC7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Smp family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41062Z9. Bacteria.
COG3726. LUCA.
HOGENOMiHOG000127853.
KOiK07186.
OMAiRQVDNTT.

Family and domain databases

InterProiIPR019305. Uncharacterised_Smp.
[Graphical view]
PfamiPF10144. SMP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AGC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARTKLKFRL HRAVIVLFCL ALLVALMQGA SWFSQNHQRQ RNPQLEELAR
60 70 80 90 100
TLARQVTLNV APLMRTDSPD EKRIQAILDQ LTDESRILDA GVYDEQGDLI
110 120 130 140 150
ARSGESVEVR DRLALDGKKA GGYFNQQIVE PIAGKNGPLG YLRLTLDTHT
160 170 180 190 200
LATEAQQVDN TTNILRLMLL LSLAIGVVLT RTLLQGKRTR WQQSPFLLTA
210
SKPVPEEEES EKKE
Length:214
Mass (Da):24,083
Last modified:December 20, 2005 - v1
Checksum:iB8D261F2D1BF304E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M30784 Genomic DNA. Translation: AAA24635.1.
X03046 Genomic DNA. Translation: CAA26853.1.
U14003 Genomic DNA. Translation: AAA97283.1.
U00096 Genomic DNA. Translation: AAC77340.1.
AP009048 Genomic DNA. Translation: BAE78376.1.
L27665 Genomic DNA. Translation: AAA21739.1.
PIRiA26227.
RefSeqiNP_418804.1. NC_000913.3.
WP_000124615.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77340; AAC77340; b4387.
BAE78376; BAE78376; BAE78376.
GeneIDi946089.
KEGGiecj:JW4350.
eco:b4387.
PATRICi32124390. VBIEscCol129921_4535.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M30784 Genomic DNA. Translation: AAA24635.1.
X03046 Genomic DNA. Translation: CAA26853.1.
U14003 Genomic DNA. Translation: AAA97283.1.
U00096 Genomic DNA. Translation: AAC77340.1.
AP009048 Genomic DNA. Translation: BAE78376.1.
L27665 Genomic DNA. Translation: AAA21739.1.
PIRiA26227.
RefSeqiNP_418804.1. NC_000913.3.
WP_000124615.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AGC7.
SMRiP0AGC7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262788. 13 interactors.
DIPiDIP-35920N.
IntActiP0AGC7. 6 interactors.
STRINGi511145.b4387.

Proteomic databases

PaxDbiP0AGC7.
PRIDEiP0AGC7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77340; AAC77340; b4387.
BAE78376; BAE78376; BAE78376.
GeneIDi946089.
KEGGiecj:JW4350.
eco:b4387.
PATRICi32124390. VBIEscCol129921_4535.

Organism-specific databases

EchoBASEiEB0944.
EcoGeneiEG10951. smp.

Phylogenomic databases

eggNOGiENOG41062Z9. Bacteria.
COG3726. LUCA.
HOGENOMiHOG000127853.
KOiK07186.
OMAiRQVDNTT.

Enzyme and pathway databases

BioCyciEcoCyc:EG10951-MONOMER.
ECOL316407:JW4350-MONOMER.

Miscellaneous databases

PROiP0AGC7.

Family and domain databases

InterProiIPR019305. Uncharacterised_Smp.
[Graphical view]
PfamiPF10144. SMP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSMP_ECOLI
AccessioniPrimary (citable) accession number: P0AGC7
Secondary accession number(s): P18838, Q2M5T0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: November 2, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.