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Protein

RNA polymerase sigma factor RpoH

Gene

rpoH

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi253 – 272H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Sigma factor
Biological processStress response, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor RpoHUniRule annotation
Alternative name(s):
RNA polymerase sigma-32 factorUniRule annotation
Gene namesi
Name:rpoHUniRule annotation
Ordered Locus Names:Z4835, ECs4310
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000939581 – 284RNA polymerase sigma factor RpoHAdd BLAST284

Proteomic databases

PRIDEiP0AGB5

Interactioni

Subunit structurei

Interacts with the RNA polymerase core enzyme.UniRule annotation

Protein-protein interaction databases

STRINGi155864.Z4835

Structurei

3D structure databases

ProteinModelPortaliP0AGB5
SMRiP0AGB5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni53 – 122Sigma-70 factor domain-2UniRule annotationAdd BLAST70
Regioni228 – 280Sigma-70 factor domain-4UniRule annotationAdd BLAST53

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi77 – 80Interaction with polymerase core subunit RpoC4

Sequence similaritiesi

Belongs to the sigma-70 factor family. RpoH subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DEK Bacteria
COG0568 LUCA
HOGENOMiHOG000270269
KOiK03089
OMAiYQRWLAE

Family and domain databases

Gene3Di1.10.10.10, 1 hit
HAMAPiMF_00961 Sigma70_RpoH, 1 hit
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR000943 RNA_pol_sigma70
IPR007627 RNA_pol_sigma70_r2
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR012759 RNA_pol_sigma_RpoH_proteobac
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF04542 Sigma70_r2, 1 hit
PF04545 Sigma70_r4, 1 hit
PIRSFiPIRSF000770 RNA_pol_sigma-SigE/K, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 1 hit
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02392 rpoH_proteo, 1 hit
TIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS00715 SIGMA70_1, 1 hit
PS00716 SIGMA70_2, 1 hit

Sequencei

Sequence statusi: Complete.

P0AGB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKMQSLAL APVGNLDSYI RAANAWPMLS ADEERALAEK LHYHGDLEAA
60 70 80 90 100
KTLILSHLRF VVHIARNYAG YGLPQADLIQ EGNIGLMKAV RRFNPEVGVR
110 120 130 140 150
LVSFAVHWIK AEIHEYVLRN WRIVKVATTK AQRKLFFNLR KTKQRLGWFN
160 170 180 190 200
QDEVEMVARE LGVTSKDVRE MESRMAAQDM TFDLSSDDDS DSQPMAPVLY
210 220 230 240 250
LQDKSSNFAD GIEDDNWEEQ AANRLTDAMQ GLDERSQDII RARWLDEDNK
260 270 280
STLQELADRY GVSAERVRQL EKNAMKKLRA AIEA
Length:284
Mass (Da):32,469
Last modified:December 20, 2005 - v1
Checksum:i628A17B4C835D00A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG58570.1
BA000007 Genomic DNA Translation: BAB37733.1
PIRiF86013
F91167
RefSeqiNP_312337.1, NC_002695.1
WP_000130217.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG58570; AAG58570; Z4835
BAB37733; BAB37733; BAB37733
GeneIDi915834
KEGGiece:Z4835
ecs:ECs4310
PATRICifig|386585.9.peg.4503

Similar proteinsi

Entry informationi

Entry nameiRPOH_ECO57
AccessioniPrimary (citable) accession number: P0AGB5
Secondary accession number(s): P00580
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: December 20, 2005
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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