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Protein

Protein-export protein SecB

Gene

secB

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciECOL386585:GJFA-4454-MONOMER.
ECOO157:SECB-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-export protein SecBUniRule annotation
Gene namesi
Name:secBUniRule annotation
Ordered Locus Names:Z5036, ECs4487
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 155155Protein-export protein SecBPRO_0000055371Add
BLAST

Proteomic databases

PRIDEiP0AG88.

Interactioni

Subunit structurei

Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.UniRule annotation

Protein-protein interaction databases

MINTiMINT-1248874.
STRINGi155864.Z5036.

Structurei

3D structure databases

ProteinModelPortaliP0AG88.
SMRiP0AG88. Positions 9-144.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105IX2. Bacteria.
COG1952. LUCA.
HOGENOMiHOG000218192.
KOiK03071.
OMAiCPNVLFP.

Family and domain databases

Gene3Di3.10.420.10. 1 hit.
HAMAPiMF_00821. SecB. 1 hit.
InterProiIPR003708. SecB.
[Graphical view]
PfamiPF02556. SecB. 1 hit.
[Graphical view]
PRINTSiPR01594. SECBCHAPRONE.
SUPFAMiSSF54611. SSF54611. 1 hit.
TIGRFAMsiTIGR00809. secB. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AG88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQNNTEMT FQIQRIYTKD ISFEAPNAPH VFQKDWQPEV KLDLDTASSQ
60 70 80 90 100
LADDVYEVVL RVTVTASLGE ETAFLCEVQQ GGIFSIAGIE GTQMAHCLGA
110 120 130 140 150
YCPNILFPYA RECITSMVSR GTFPQLNLAP VNFDALFMNY LQQQAGEGTE

EHQDA
Length:155
Mass (Da):17,277
Last modified:December 20, 2005 - v1
Checksum:i00514C5F393A643D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58756.1.
BA000007 Genomic DNA. Translation: BAB37910.1.
PIRiG91189.
H86036.
RefSeqiNP_312514.1. NC_002695.1.
WP_000003377.1. NZ_LPWC01000147.1.

Genome annotation databases

EnsemblBacteriaiAAG58756; AAG58756; Z5036.
BAB37910; BAB37910; BAB37910.
GeneIDi915570.
KEGGiece:Z5036.
ecs:ECs4487.
PATRICi18358591. VBIEscCol44059_4461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58756.1.
BA000007 Genomic DNA. Translation: BAB37910.1.
PIRiG91189.
H86036.
RefSeqiNP_312514.1. NC_002695.1.
WP_000003377.1. NZ_LPWC01000147.1.

3D structure databases

ProteinModelPortaliP0AG88.
SMRiP0AG88. Positions 9-144.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1248874.
STRINGi155864.Z5036.

Proteomic databases

PRIDEiP0AG88.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG58756; AAG58756; Z5036.
BAB37910; BAB37910; BAB37910.
GeneIDi915570.
KEGGiece:Z5036.
ecs:ECs4487.
PATRICi18358591. VBIEscCol44059_4461.

Phylogenomic databases

eggNOGiENOG4105IX2. Bacteria.
COG1952. LUCA.
HOGENOMiHOG000218192.
KOiK03071.
OMAiCPNVLFP.

Enzyme and pathway databases

BioCyciECOL386585:GJFA-4454-MONOMER.
ECOO157:SECB-MONOMER.

Family and domain databases

Gene3Di3.10.420.10. 1 hit.
HAMAPiMF_00821. SecB. 1 hit.
InterProiIPR003708. SecB.
[Graphical view]
PfamiPF02556. SecB. 1 hit.
[Graphical view]
PRINTSiPR01594. SECBCHAPRONE.
SUPFAMiSSF54611. SSF54611. 1 hit.
TIGRFAMsiTIGR00809. secB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSECB_ECO57
AccessioniPrimary (citable) accession number: P0AG88
Secondary accession number(s): P15040
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: September 7, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.