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Protein

Sulfate-binding protein

Gene

sbp

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein specifically binds sulfate and is involved in its transmembrane transport.

GO - Molecular functioni

  • ATPase-coupled sulfate transmembrane transporter activity Source: InterPro
  • sulfate binding Source: EcoCyc

GO - Biological processi

  • sulfate transport Source: EcoCyc
  • sulfur compound metabolic process Source: EcoCyc

Keywordsi

Biological processSulfate transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:SBP-MONOMER
MetaCyc:SBP-MONOMER

Protein family/group databases

TCDBi3.A.1.6.1 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfate-binding protein
Alternative name(s):
Sulfate starvation-induced protein 2
Short name:
SSI2
Gene namesi
Name:sbp
Ordered Locus Names:b3917, JW3888
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10929 sbp

Subcellular locationi

GO - Cellular componenti

  • outer membrane-bounded periplasmic space Source: EcoCyc

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 192 PublicationsAdd BLAST19
ChainiPRO_000003168320 – 329Sulfate-binding proteinAdd BLAST310

Proteomic databases

PaxDbiP0AG78
PRIDEiP0AG78

2D gel databases

SWISS-2DPAGEP0AG78

Expressioni

Inductioni

Repressed by sulfate or cysteine.

Interactioni

Protein-protein interaction databases

BioGridi4261220, 30 interactors
DIPiDIP-35843N
IntActiP0AG78, 11 interactors
STRINGi316385.ECDH10B_4106

Structurei

3D structure databases

ProteinModelPortaliP0AG78
SMRiP0AG78
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105DE7 Bacteria
COG1613 LUCA
HOGENOMiHOG000260057
InParanoidiP0AG78
KOiK02048
OMAiKDFGGWK
PhylomeDBiP0AG78

Family and domain databases

CDDicd01005 PBP2_CysP, 1 hit
InterProiView protein in InterPro
IPR000957 Sulphate/thiosulphate-bd_CS
IPR034408 Sulphate/thiosulphate_BS
IPR005669 Thiosulph/SO4-bd
PANTHERiPTHR30368 PTHR30368, 1 hit
TIGRFAMsiTIGR00971 3a0106s03, 1 hit
PROSITEiView protein in PROSITE
PS00401 PROK_SULFATE_BIND_1, 1 hit
PS00757 PROK_SULFATE_BIND_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AG78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKWGVGLTF LLAATSVMAK DIQLLNVSYD PTRELYEQYN KAFSAHWKQQ
60 70 80 90 100
TGDNVVIRQS HGGSGKQATS VINGIEADVV TLALAYDVDA IAERGRIDKE
110 120 130 140 150
WIKRLPDNSA PYTSTIVFLV RKGNPKQIHD WNDLIKPGVS VITPNPKSSG
160 170 180 190 200
GARWNYLAAW GYALHHNNND QAKAQDFVRA LYKNVEVLDS GARGSTNTFV
210 220 230 240 250
ERGIGDVLIA WENEALLAAN ELGKDKFEIV TPSESILAEP TVSVVDKVVE
260 270 280 290 300
KKGTKEVAEA YLKYLYSPEG QEIAAKNYYR PRDAEVAKKY ENAFPKLKLF
310 320
TIDEEFGGWT KAQKEHFANG GTFDQISKR
Length:329
Mass (Da):36,659
Last modified:December 20, 2005 - v1
Checksum:i3353D36DE484C814
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti185V → E in CAA26357 (PubMed:3158524).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02519 Genomic DNA Translation: CAA26357.1 Sequence problems.
L19201 Genomic DNA Translation: AAB03049.1
U00096 Genomic DNA Translation: AAC76899.1
AP009048 Genomic DNA Translation: BAE77393.1
PIRiS40860 BYEC
RefSeqiNP_418352.1, NC_000913.3
WP_001045689.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76899; AAC76899; b3917
BAE77393; BAE77393; BAE77393
GeneIDi948411
KEGGiecj:JW3888
eco:b3917
PATRICifig|1411691.4.peg.2788

Entry informationi

Entry nameiSUBI_ECOLI
AccessioniPrimary (citable) accession number: P0AG78
Secondary accession number(s): P06997, Q2M8L3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health