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P0AG42 (RIBF_ECO57) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Riboflavin biosynthesis protein RibF

Including the following 2 domains:

  1. Riboflavin kinase
    EC=2.7.1.26
    Alternative name(s):
    Flavokinase
  2. FMN adenylyltransferase
    EC=2.7.7.2
    Alternative name(s):
    FAD pyrophosphorylase
    FAD synthase
Gene names
Name:ribF
Ordered Locus Names:Z0029, ECs0028
OrganismEscherichia coli O157:H7 [Complete proteome] [HAMAP]
Taxonomic identifier83334 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + riboflavin = ADP + FMN.

ATP + FMN = diphosphate + FAD.

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.

Sequence similarities

Belongs to the RibF family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 313313Riboflavin biosynthesis protein RibF
PRO_0000194138

Sequences

Sequence LengthMass (Da)Tools
P0AG42 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: C0B2EF5499CD30FE

FASTA31334,734
        10         20         30         40         50         60 
MKLIRGIHNL SQAPQEGCVL TIGNFDGVHR GHRALLQGLQ EEGRKRNLPV MVMLFEPQPL 

        70         80         90        100        110        120 
ELFATDKAPA RLTRLREKLR YLAECGVDYV LCVRFDRRFA ALTAQNFISD LLVKHLRVKF 

       130        140        150        160        170        180 
LAVGDDFRFG AGREGDFLLL QKAGMEYGFD ITSTQTFCEG GVRISSTAVR QALADDNLAL 

       190        200        210        220        230        240 
AESLLGHPFA ISGRVVHGDE LGRTIGFPTA NVPLRRQVSP VKGVYAVEVL GLGEKPLPGV 

       250        260        270        280        290        300 
ANIGTRPTVA GIRQQLEVHL LDVAMDLYGR HIQVVLRKKI RNEQRFASLD ELKAQIARDE 

       310 
LTAREFFGLT KPA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005174 Genomic DNA. Translation: AAG54327.1.
BA000007 Genomic DNA. Translation: BAB33451.1.
PIRC85483.
D90632.
RefSeqNP_285719.1. NC_002655.2.
NP_308055.1. NC_002695.1.

3D structure databases

ProteinModelPortalP0AG42.
SMRP0AG42. Positions 19-306.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-1256494.
STRING155864.Z0029.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG54327; AAG54327; Z0029.
BAB33451; BAB33451; BAB33451.
GeneID913423.
956690.
KEGGece:Z0029.
ecs:ECs0028.
PATRIC18348988. VBIEscCol44059_0024.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0196.
HOGENOMHOG000006845.
KOK11753.
OMAGVASFGC.
OrthoDBEOG6QP0ZV.

Enzyme and pathway databases

BioCycECOL386585:GJFA-26-MONOMER.
ECOO157:RIBF-MONOMER.
UniPathwayUPA00276; UER00406.
UPA00277; UER00407.

Family and domain databases

Gene3D2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProIPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR22749. PTHR22749. 1 hit.
PfamPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFPIRSF004491. FAD_Synth. 1 hit.
SMARTSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMSSF82114. SSF82114. 1 hit.
TIGRFAMsTIGR00083. ribF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBF_ECO57
AccessionPrimary (citable) accession number: P0AG42
Secondary accession number(s): P08391, P75621
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: December 20, 2005
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways