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Protein

Threonine efflux protein

Gene

rhtC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Conducts the efflux of threonine.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:RHTC-MONOMER
MetaCyc:RHTC-MONOMER

Protein family/group databases

TCDBi2.A.76.1.2 the resistance to homoserine/threonine (rhtb) family

Names & Taxonomyi

Protein namesi
Recommended name:
Threonine efflux protein
Gene namesi
Name:rhtC
Synonyms:yigJ
Ordered Locus Names:b3823, JW5586
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11468 rhtC

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalSequence analysisAdd BLAST21
Topological domaini22 – 43PeriplasmicSequence analysisAdd BLAST22
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Topological domaini65 – 66CytoplasmicSequence analysis2
Transmembranei67 – 87HelicalSequence analysisAdd BLAST21
Topological domaini88 – 149PeriplasmicSequence analysisAdd BLAST62
Transmembranei150 – 173HelicalSequence analysisAdd BLAST24
Topological domaini174 – 206CytoplasmicSequence analysisAdd BLAST33

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000947361 – 206Threonine efflux proteinAdd BLAST206

Proteomic databases

PaxDbiP0AG38
PRIDEiP0AG38

Interactioni

Protein-protein interaction databases

BioGridi4263363, 8 interactors
STRINGi316385.ECDH10B_4014

Structurei

3D structure databases

ProteinModelPortaliP0AG38
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Rht family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CCF Bacteria
COG1280 LUCA
HOGENOMiHOG000122945
InParanoidiP0AG38
KOiK05835
OMAiDFFYVSR
PhylomeDBiP0AG38

Family and domain databases

InterProiView protein in InterPro
IPR004778 Homoserine/Threonine_efflux
IPR001123 LeuE-type
PANTHERiPTHR30086 PTHR30086, 1 hit
PfamiView protein in Pfam
PF01810 LysE, 1 hit
PIRSFiPIRSF006324 LeuE, 1 hit
TIGRFAMsiTIGR00949 2A76, 1 hit

Sequencei

Sequence statusi: Complete.

P0AG38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLMLFLTVAM VHIVALMSPG PDFFFVSQTA VSRSRKEAMM GVLGITCGVM
60 70 80 90 100
VWAGIALLGL HLIIEKMAWL HTLIMVGGGL YLCWMGYQML RGALKKEAVS
110 120 130 140 150
APAPQVELAK SGRSFLKGLL TNLANPKAII YFGSVFSLFV GDNVGTTARW
160 170 180 190 200
GIFALIIVET LAWFTVVASL FALPQMRRGY QRLAKWIDGF AGALFAGFGI

HLIISR
Length:206
Mass (Da):22,474
Last modified:December 20, 2005 - v1
Checksum:iF64017878CC6D50D
GO

Sequence cautioni

The sequence AAA67619 differs from that shown. Reason: Frameshift at positions 80 and 118.Curated
The sequence M30198 differs from that shown. Reason: Frameshift at positions 47 and 73.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M87049 Genomic DNA Translation: AAA67619.1 Frameshift.
U00096 Genomic DNA Translation: AAT48222.1
AP009048 Genomic DNA Translation: BAE77478.1
M30198 Genomic DNA No translation available.
RefSeqiWP_000928824.1, NZ_LN832404.1
YP_026264.1, NC_000913.3

Genome annotation databases

EnsemblBacteriaiAAT48222; AAT48222; b3823
BAE77478; BAE77478; BAE77478
GeneIDi948317
KEGGiecj:JW5586
eco:b3823
PATRICifig|1411691.4.peg.2884

Similar proteinsi

Entry informationi

Entry nameiRHTC_ECOLI
AccessioniPrimary (citable) accession number: P0AG38
Secondary accession number(s): P27846, Q2M8C8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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