Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribulose-phosphate 3-epimerase

Gene

rpe

Organism
Shigella flexneri
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.By similarity

Catalytic activityi

D-ribulose 5-phosphate = D-xylulose 5-phosphate.

Cofactori

Co2+By similarity, Fe2+By similarity, Mn2+By similarity, Zn2+By similarityNote: Binds 1 divalent metal cation per subunit. Active with Co2+, Fe2+, Mn2+ and Zn2+.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei9SubstrateBy similarity1
Metal bindingi34Divalent metal cationBy similarity1
Active sitei36Proton acceptorBy similarity1
Metal bindingi36Divalent metal cationBy similarity1
Metal bindingi68Divalent metal cationBy similarity1
Binding sitei68SubstrateBy similarity1
Active sitei177Proton donorBy similarity1
Metal bindingi177Divalent metal cationBy similarity1
Binding sitei179Substrate; via amide nitrogenBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism
LigandCobalt, Iron, Manganese, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose-phosphate 3-epimerase (EC:5.1.3.1)
Alternative name(s):
Pentose-5-phosphate 3-epimerase
Short name:
PPE
R5P3E
Gene namesi
Name:rpe
Ordered Locus Names:SF3404, S4358
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001715801 – 225Ribulose-phosphate 3-epimeraseAdd BLAST225

Structurei

3D structure databases

ProteinModelPortaliP0AG10
SMRiP0AG10
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni144 – 147Substrate bindingBy similarity4
Regioni199 – 200Substrate bindingBy similarity2

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105DJV Bacteria
COG0036 LUCA
HOGENOMiHOG000259347
KOiK01783
OMAiCHLMIED

Family and domain databases

CDDicd00429 RPE, 1 hit
Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR026019 Ribul_P_3_epim
IPR000056 Ribul_P_3_epim-like
IPR011060 RibuloseP-bd_barrel
PANTHERiPTHR11749 PTHR11749, 1 hit
PfamiView protein in Pfam
PF00834 Ribul_P_3_epim, 1 hit
PIRSFiPIRSF001461 RPE, 1 hit
SUPFAMiSSF51366 SSF51366, 1 hit
TIGRFAMsiTIGR01163 rpe, 1 hit
PROSITEiView protein in PROSITE
PS01085 RIBUL_P_3_EPIMER_1, 1 hit
PS01086 RIBUL_P_3_EPIMER_2, 1 hit

Sequencei

Sequence statusi: Complete.

P0AG10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQYLIAPSI LSADFARLGE DTAKALAAGA DVVHFDVMDN HYVPNLTIGP
60 70 80 90 100
MVLKSLRNYG ITAPIDVHLM VKPVDRIVPD FAAAGASIIT FHPEASEHVD
110 120 130 140 150
RTLQLIKENG CKAGLVFNPA TPLSYLDYVM DKLDVILLMS VNPGFGGQSF
160 170 180 190 200
IPQTLDKLRE VRRRIDESGF DIRLEVDGGV KVNNIGEIAA AGADMFVAGS
210 220
AIFDQPDYKK VIDEMRSELA KVSHE
Length:225
Mass (Da):24,554
Last modified:December 20, 2005 - v1
Checksum:iDD678085698466FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN44866.1
AE014073 Genomic DNA Translation: AAP19312.1
RefSeqiNP_709159.1, NC_004337.2
WP_000816280.1, NZ_NIYV01000043.1

Genome annotation databases

EnsemblBacteriaiAAN44866; AAN44866; SF3404
AAP19312; AAP19312; S4358
GeneIDi1026889
KEGGisfl:SF3404
sfx:S4358
PATRICifig|198214.7.peg.4018

Similar proteinsi

Entry informationi

Entry nameiRPE_SHIFL
AccessioniPrimary (citable) accession number: P0AG10
Secondary accession number(s): P32661
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health