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Protein

Protein SanA

Gene

sanA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Participates in the barrier function of the cell envelope.

GO - Biological processi

  • response to drug Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:EG12025-MONOMER

Protein family/group databases

TCDBi9.B.114.1.1 the vancomycin-sensitivity protein (sana) family

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SanA
Gene namesi
Name:sanA
Synonyms:yeiF
Ordered Locus Names:b2144, JW2132
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12025 sanA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 6CytoplasmicSequence analysis6
Transmembranei7 – 23HelicalSequence analysisAdd BLAST17
Topological domaini24 – 239PeriplasmicSequence analysisAdd BLAST216

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000975761 – 239Protein SanAAdd BLAST239

Proteomic databases

PaxDbiP0AFY2
PRIDEiP0AFY2

Interactioni

Protein-protein interaction databases

BioGridi42591677 interactors.
IntActiP0AFY2 2 interactors.
STRINGi316385.ECDH10B_2301

Structurei

3D structure databases

ProteinModelPortaliP0AFY2
SMRiP0AFY2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107GZ4 Bacteria
COG2949 LUCA
HOGENOMiHOG000031180
InParanoidiP0AFY2
KOiK03748
OMAiYDEPDAM
PhylomeDBiP0AFY2

Family and domain databases

CDDicd06259 YdcF-like, 1 hit
InterProiView protein in InterPro
IPR003848 DUF218
IPR023604 Uncharacterised_SanA
PfamiView protein in Pfam
PF02698 DUF218, 1 hit
PIRSFiPIRSF005011 SanA, 1 hit

Sequencei

Sequence statusi: Complete.

P0AFY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKRVFLSLL VLIGLLLLTV LGLDRWMSWK TAPYIYDELQ DLPYRQVGVV
60 70 80 90 100
LGTAKYYRTG VINQYYRYRI QGAINAYNSG KVNYLLLSGD NALQSYNEPM
110 120 130 140 150
TMRKDLIAAG VDPSDIVLDY AGFRTLDSIV RTRKVFDTND FIIITQRFHC
160 170 180 190 200
ERALFIALHM GIQAQCYAVP SPKDMLSVRI REFAARFGAL ADLYIFKREP
210 220 230
RFLGPLVPIP AMHQVPEDAQ GYPAVTPEQL LELQKKQGK
Length:239
Mass (Da):27,287
Last modified:December 20, 2005 - v1
Checksum:i574EF9B02249547C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti156 – 239IALHM…KKQGK → MRCIWDSGSVLCRTVTERYA VSTYS (PubMed:8550448).CuratedAdd BLAST84

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z47804 Genomic DNA Translation: CAA87766.1
U00096 Genomic DNA Translation: AAC75205.1
AP009048 Genomic DNA Translation: BAE76621.1
U00007 Genomic DNA Translation: AAA60509.1
M60916 Genomic DNA No translation available.
PIRiG64982
RefSeqiNP_416649.1, NC_000913.3
WP_000920064.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75205; AAC75205; b2144
BAE76621; BAE76621; BAE76621
GeneIDi949003
KEGGiecj:JW2132
eco:b2144
PATRICifig|1411691.4.peg.98

Similar proteinsi

Entry informationi

Entry nameiSANA_ECOLI
AccessioniPrimary (citable) accession number: P0AFY2
Secondary accession number(s): P33017, P76438, Q2MAT5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome