Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative magnesium transporter YhiD

Gene

yhiD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Could be involved in magnesium uptake.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciEcoCyc:EG11400-MONOMER.
ECOL316407:JW5670-MONOMER.

Protein family/group databases

TCDBi9.B.20.1.4. the putative mg(2+) transporter-c (mgtc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative magnesium transporter YhiD
Gene namesi
Name:yhiD
Synonyms:yhhE
Ordered Locus Names:b3508, JW5670
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11400. yhiD.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalSequence analysisAdd
BLAST
Transmembranei36 – 5621HelicalSequence analysisAdd
BLAST
Transmembranei67 – 8721HelicalSequence analysisAdd
BLAST
Transmembranei92 – 11221HelicalSequence analysisAdd
BLAST
Transmembranei118 – 13821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Deletion of yhiD in addition to mgtA and corA leads to Mg2+ auxotrophy.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 215215Putative magnesium transporter YhiDPRO_0000202032Add
BLAST

Proteomic databases

PaxDbiP0AFV2.

Interactioni

Protein-protein interaction databases

BioGridi4261142. 6 interactions.
STRINGi511145.b3508.

Structurei

3D structure databases

ProteinModelPortaliP0AFV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MgtC/SapB family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105KT7. Bacteria.
COG1285. LUCA.
HOGENOMiHOG000080250.
InParanoidiP0AFV2.
KOiK07507.
OMAiNIHDINI.
OrthoDBiEOG62K216.
PhylomeDBiP0AFV2.

Family and domain databases

InterProiIPR003416. MgtC/SapB/SrpB/YhiD_fam.
[Graphical view]
PfamiPF02308. MgtC. 1 hit.
[Graphical view]
PRINTSiPR01837. MGTCSAPBPROT.

Sequencei

Sequence statusi: Complete.

P0AFV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAEFIIRLI LAAIACGAIG MERQMRGKGA GLRTHVLIGM GSALFMIVSK
60 70 80 90 100
YGFADVLSLD HVGLDPSRIA AQVVTGVGFI GAGNILVRNQ NIVGLTTAAD
110 120 130 140 150
IWVTAAIGMV IGSGMYELGI YGSVMTLLVL EVFHQLTFRL MNKNYHLQLT
160 170 180 190 200
LVNGNTVSML DWFKQQKIKT DLVSLQENED HEVVAIDIQL HATTSIEDLL
210
RLLKGMAGVK GVSIS
Length:215
Mass (Da):23,213
Last modified:December 20, 2005 - v1
Checksum:i4F3E986281C3CF99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18484.1.
U00096 Genomic DNA. Translation: AAC76533.1.
AP009048 Genomic DNA. Translation: BAE77786.1.
D11109 Genomic DNA. Translation: BAA01885.1.
PIRiS47728.
RefSeqiNP_417965.1. NC_000913.3.
WP_001296814.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76533; AAC76533; b3508.
BAE77786; BAE77786; BAE77786.
GeneIDi948019.
KEGGiecj:JW5670.
eco:b3508.
PATRICi32122474. VBIEscCol129921_3615.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18484.1.
U00096 Genomic DNA. Translation: AAC76533.1.
AP009048 Genomic DNA. Translation: BAE77786.1.
D11109 Genomic DNA. Translation: BAA01885.1.
PIRiS47728.
RefSeqiNP_417965.1. NC_000913.3.
WP_001296814.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFV2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261142. 6 interactions.
STRINGi511145.b3508.

Protein family/group databases

TCDBi9.B.20.1.4. the putative mg(2+) transporter-c (mgtc) family.

Proteomic databases

PaxDbiP0AFV2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76533; AAC76533; b3508.
BAE77786; BAE77786; BAE77786.
GeneIDi948019.
KEGGiecj:JW5670.
eco:b3508.
PATRICi32122474. VBIEscCol129921_3615.

Organism-specific databases

EchoBASEiEB1372.
EcoGeneiEG11400. yhiD.

Phylogenomic databases

eggNOGiENOG4105KT7. Bacteria.
COG1285. LUCA.
HOGENOMiHOG000080250.
InParanoidiP0AFV2.
KOiK07507.
OMAiNIHDINI.
OrthoDBiEOG62K216.
PhylomeDBiP0AFV2.

Enzyme and pathway databases

BioCyciEcoCyc:EG11400-MONOMER.
ECOL316407:JW5670-MONOMER.

Miscellaneous databases

PROiP0AFV2.

Family and domain databases

InterProiIPR003416. MgtC/SapB/SrpB/YhiD_fam.
[Graphical view]
PfamiPF02308. MgtC. 1 hit.
[Graphical view]
PRINTSiPR01837. MGTCSAPBPROT.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes."
    Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.
    Nucleic Acids Res. 22:2576-2586(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Function of the Escherichia coli nucleoid protein, H-NS: molecular analysis of a subset of proteins whose expression is enhanced in a hns deletion mutant."
    Yoshida T., Ueguchi C., Yamada H., Mizuno T.
    Mol. Gen. Genet. 237:113-122(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-148.
    Strain: K12.
  5. "Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+) homeostasis."
    Hattori M., Iwase N., Furuya N., Tanaka Y., Tsukazaki T., Ishitani R., Maguire M.E., Ito K., Maturana A., Nureki O.
    EMBO J. 28:3602-3612(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.

Entry informationi

Entry nameiYHID_ECOLI
AccessioniPrimary (citable) accession number: P0AFV2
Secondary accession number(s): P26606, Q2M7H0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: April 13, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.