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Protein

Uncharacterized transporter YfbS

Gene

yfbS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7186-MONOMER.
ECOL316407:JW2289-MONOMER.

Protein family/group databases

TCDBi2.A.47.4.8. the divalent anion:na(+) symporter (dass) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized transporter YfbS
Gene namesi
Name:yfbS
Ordered Locus Names:b2292, JW2289
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14103. yfbS.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalSequence analysisAdd BLAST21
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21
Transmembranei51 – 71HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Transmembranei175 – 195HelicalSequence analysisAdd BLAST21
Transmembranei373 – 393HelicalSequence analysisAdd BLAST21
Transmembranei425 – 445HelicalSequence analysisAdd BLAST21
Transmembranei464 – 484HelicalSequence analysisAdd BLAST21
Transmembranei503 – 523HelicalSequence analysisAdd BLAST21
Transmembranei543 – 563HelicalSequence analysisAdd BLAST21
Transmembranei588 – 608HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001725031 – 610Uncharacterized transporter YfbSAdd BLAST610

Proteomic databases

PaxDbiP0AFU2.
PRIDEiP0AFU2.

Interactioni

Protein-protein interaction databases

BioGridi4262968. 210 interactors.
DIPiDIP-48033N.
IntActiP0AFU2. 1 interactor.
MINTiMINT-1256616.
STRINGi511145.b2292.

Structurei

3D structure databases

ProteinModelPortaliP0AFU2.
SMRiP0AFU2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini218 – 307RCK C-terminal 1PROSITE-ProRule annotationAdd BLAST90
Domaini314 – 398RCK C-terminal 2PROSITE-ProRule annotationAdd BLAST85

Sequence similaritiesi

Contains 2 RCK C-terminal domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QWE. Bacteria.
COG0471. LUCA.
HOGENOMiHOG000281279.
InParanoidiP0AFU2.
OMAiGKIPLKF.
PhylomeDBiP0AFU2.

Family and domain databases

Gene3Di3.30.70.1450. 2 hits.
InterProiIPR004680. Cit_transptr-like_dom.
IPR031312. Na/sul_symport_CS.
IPR006037. RCK_C.
[Graphical view]
PfamiPF03600. CitMHS. 2 hits.
PF02080. TrkA_C. 2 hits.
[Graphical view]
SUPFAMiSSF116726. SSF116726. 2 hits.
PROSITEiPS01271. NA_SULFATE. 1 hit.
PS51202. RCK_C. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGELIWVLS LLAVAIVLFA TGRVRMDAVA LFVIVAFALS GTLTVPEVFS
60 70 80 90 100
GFSDPNVVLI AALFIIGDGL VRTGVATVMG TWLVKVAGNS EIKMLVLLML
110 120 130 140 150
TVAGLGAFMS STGVVAIFIP VVLSVAMRMQ TSPSRLMMPL SFAGLISGMM
160 170 180 190 200
TLVATPPNLV VNSELLREGY HGFSFFSVTP IGLVVLVLGI LYMLVMRFML
210 220 230 240 250
KGDTQTPQRE GWTRRTFRDL IREYRLTGRA RRLAIRPGSP MIGQRLDDLK
260 270 280 290 300
LRERYGANVI GVERWRRFRR VIVNVNGVSE FRARDVLLID MSAADVDLRQ
310 320 330 340 350
FCSEQLLEPM VLRGEYFSDQ ALDVGMAEIS LIPESELIGK SVREIGFRTR
360 370 380 390 400
YGLNVVGLKR NGVALEGSLA DEPLLLGDII LVVGNWKLIG MLAKQGRDFV
410 420 430 440 450
ALNLPEEVSE ASPAHSQAPH AIFCLVLMVA LMLTDEIPNP VAAIIACLLM
460 470 480 490 500
GKFRCIDAES AYKSIHWPSI ILIVGMMPFA VALQKTGGVA LAVKGLMDIG
510 520 530 540 550
GGYGPHMMLG CLFVLSAVIG LFISNTATAV LMAPIALAAA KTMGVSPYPF
560 570 580 590 600
AMVVAMAASA AFMTPVSSPV NTLVLGPGNY SFSDFVKLGV PFTIIVMAVC
610
VVMIPMLFPF
Length:610
Mass (Da):65,872
Last modified:December 20, 2005 - v1
Checksum:i57100587B0F54C9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75352.1.
AP009048 Genomic DNA. Translation: BAA16128.1.
PIRiB65001.
RefSeqiNP_416795.1. NC_000913.3.
WP_001012899.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75352; AAC75352; b2292.
BAA16128; BAA16128; BAA16128.
GeneIDi946766.
KEGGiecj:JW2289.
eco:b2292.
PATRICi32119953. VBIEscCol129921_2386.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75352.1.
AP009048 Genomic DNA. Translation: BAA16128.1.
PIRiB65001.
RefSeqiNP_416795.1. NC_000913.3.
WP_001012899.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFU2.
SMRiP0AFU2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262968. 210 interactors.
DIPiDIP-48033N.
IntActiP0AFU2. 1 interactor.
MINTiMINT-1256616.
STRINGi511145.b2292.

Protein family/group databases

TCDBi2.A.47.4.8. the divalent anion:na(+) symporter (dass) family.

Proteomic databases

PaxDbiP0AFU2.
PRIDEiP0AFU2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75352; AAC75352; b2292.
BAA16128; BAA16128; BAA16128.
GeneIDi946766.
KEGGiecj:JW2289.
eco:b2292.
PATRICi32119953. VBIEscCol129921_2386.

Organism-specific databases

EchoBASEiEB3856.
EcoGeneiEG14103. yfbS.

Phylogenomic databases

eggNOGiENOG4107QWE. Bacteria.
COG0471. LUCA.
HOGENOMiHOG000281279.
InParanoidiP0AFU2.
OMAiGKIPLKF.
PhylomeDBiP0AFU2.

Enzyme and pathway databases

BioCyciEcoCyc:G7186-MONOMER.
ECOL316407:JW2289-MONOMER.

Miscellaneous databases

PROiP0AFU2.

Family and domain databases

Gene3Di3.30.70.1450. 2 hits.
InterProiIPR004680. Cit_transptr-like_dom.
IPR031312. Na/sul_symport_CS.
IPR006037. RCK_C.
[Graphical view]
PfamiPF03600. CitMHS. 2 hits.
PF02080. TrkA_C. 2 hits.
[Graphical view]
SUPFAMiSSF116726. SSF116726. 2 hits.
PROSITEiPS01271. NA_SULFATE. 1 hit.
PS51202. RCK_C. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFBS_ECOLI
AccessioniPrimary (citable) accession number: P0AFU2
Secondary accession number(s): P76935, P77741
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: November 2, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.