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Protein

Uncharacterized transporter YfbS

Gene

yfbS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7186-MONOMER.
ECOL316407:JW2289-MONOMER.

Protein family/group databases

TCDBi2.A.47.4.8. the divalent anion:na(+) symporter (dass) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized transporter YfbS
Gene namesi
Name:yfbS
Ordered Locus Names:b2292, JW2289
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14103. yfbS.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalSequence analysisAdd
BLAST
Transmembranei29 – 4921HelicalSequence analysisAdd
BLAST
Transmembranei51 – 7121HelicalSequence analysisAdd
BLAST
Transmembranei78 – 9821HelicalSequence analysisAdd
BLAST
Transmembranei102 – 12221HelicalSequence analysisAdd
BLAST
Transmembranei136 – 15621HelicalSequence analysisAdd
BLAST
Transmembranei175 – 19521HelicalSequence analysisAdd
BLAST
Transmembranei373 – 39321HelicalSequence analysisAdd
BLAST
Transmembranei425 – 44521HelicalSequence analysisAdd
BLAST
Transmembranei464 – 48421HelicalSequence analysisAdd
BLAST
Transmembranei503 – 52321HelicalSequence analysisAdd
BLAST
Transmembranei543 – 56321HelicalSequence analysisAdd
BLAST
Transmembranei588 – 60821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 610610Uncharacterized transporter YfbSPRO_0000172503Add
BLAST

Proteomic databases

EPDiP0AFU2.
PaxDbiP0AFU2.
PRIDEiP0AFU2.

Interactioni

Protein-protein interaction databases

BioGridi4262968. 210 interactions.
DIPiDIP-48033N.
IntActiP0AFU2. 1 interaction.
MINTiMINT-1256616.
STRINGi511145.b2292.

Structurei

3D structure databases

ProteinModelPortaliP0AFU2.
SMRiP0AFU2. Positions 9-197, 439-608.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini218 – 30790RCK C-terminal 1PROSITE-ProRule annotationAdd
BLAST
Domaini314 – 39885RCK C-terminal 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 RCK C-terminal domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QWE. Bacteria.
COG0471. LUCA.
HOGENOMiHOG000281279.
InParanoidiP0AFU2.
OMAiGKIPLKF.
OrthoDBiEOG6RVFS4.
PhylomeDBiP0AFU2.

Family and domain databases

Gene3Di3.30.70.1450. 2 hits.
InterProiIPR004680. Cit_transptr-like_dom.
IPR031312. Na/sul_symport_CS.
IPR006037. RCK_C.
[Graphical view]
PfamiPF03600. CitMHS. 2 hits.
PF02080. TrkA_C. 2 hits.
[Graphical view]
SUPFAMiSSF116726. SSF116726. 2 hits.
PROSITEiPS01271. NA_SULFATE. 1 hit.
PS51202. RCK_C. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGELIWVLS LLAVAIVLFA TGRVRMDAVA LFVIVAFALS GTLTVPEVFS
60 70 80 90 100
GFSDPNVVLI AALFIIGDGL VRTGVATVMG TWLVKVAGNS EIKMLVLLML
110 120 130 140 150
TVAGLGAFMS STGVVAIFIP VVLSVAMRMQ TSPSRLMMPL SFAGLISGMM
160 170 180 190 200
TLVATPPNLV VNSELLREGY HGFSFFSVTP IGLVVLVLGI LYMLVMRFML
210 220 230 240 250
KGDTQTPQRE GWTRRTFRDL IREYRLTGRA RRLAIRPGSP MIGQRLDDLK
260 270 280 290 300
LRERYGANVI GVERWRRFRR VIVNVNGVSE FRARDVLLID MSAADVDLRQ
310 320 330 340 350
FCSEQLLEPM VLRGEYFSDQ ALDVGMAEIS LIPESELIGK SVREIGFRTR
360 370 380 390 400
YGLNVVGLKR NGVALEGSLA DEPLLLGDII LVVGNWKLIG MLAKQGRDFV
410 420 430 440 450
ALNLPEEVSE ASPAHSQAPH AIFCLVLMVA LMLTDEIPNP VAAIIACLLM
460 470 480 490 500
GKFRCIDAES AYKSIHWPSI ILIVGMMPFA VALQKTGGVA LAVKGLMDIG
510 520 530 540 550
GGYGPHMMLG CLFVLSAVIG LFISNTATAV LMAPIALAAA KTMGVSPYPF
560 570 580 590 600
AMVVAMAASA AFMTPVSSPV NTLVLGPGNY SFSDFVKLGV PFTIIVMAVC
610
VVMIPMLFPF
Length:610
Mass (Da):65,872
Last modified:December 20, 2005 - v1
Checksum:i57100587B0F54C9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75352.1.
AP009048 Genomic DNA. Translation: BAA16128.1.
PIRiB65001.
RefSeqiNP_416795.1. NC_000913.3.
WP_001012899.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75352; AAC75352; b2292.
BAA16128; BAA16128; BAA16128.
GeneIDi946766.
KEGGiecj:JW2289.
eco:b2292.
PATRICi32119953. VBIEscCol129921_2386.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75352.1.
AP009048 Genomic DNA. Translation: BAA16128.1.
PIRiB65001.
RefSeqiNP_416795.1. NC_000913.3.
WP_001012899.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFU2.
SMRiP0AFU2. Positions 9-197, 439-608.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262968. 210 interactions.
DIPiDIP-48033N.
IntActiP0AFU2. 1 interaction.
MINTiMINT-1256616.
STRINGi511145.b2292.

Protein family/group databases

TCDBi2.A.47.4.8. the divalent anion:na(+) symporter (dass) family.

Proteomic databases

EPDiP0AFU2.
PaxDbiP0AFU2.
PRIDEiP0AFU2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75352; AAC75352; b2292.
BAA16128; BAA16128; BAA16128.
GeneIDi946766.
KEGGiecj:JW2289.
eco:b2292.
PATRICi32119953. VBIEscCol129921_2386.

Organism-specific databases

EchoBASEiEB3856.
EcoGeneiEG14103. yfbS.

Phylogenomic databases

eggNOGiENOG4107QWE. Bacteria.
COG0471. LUCA.
HOGENOMiHOG000281279.
InParanoidiP0AFU2.
OMAiGKIPLKF.
OrthoDBiEOG6RVFS4.
PhylomeDBiP0AFU2.

Enzyme and pathway databases

BioCyciEcoCyc:G7186-MONOMER.
ECOL316407:JW2289-MONOMER.

Miscellaneous databases

PROiP0AFU2.

Family and domain databases

Gene3Di3.30.70.1450. 2 hits.
InterProiIPR004680. Cit_transptr-like_dom.
IPR031312. Na/sul_symport_CS.
IPR006037. RCK_C.
[Graphical view]
PfamiPF03600. CitMHS. 2 hits.
PF02080. TrkA_C. 2 hits.
[Graphical view]
SUPFAMiSSF116726. SSF116726. 2 hits.
PROSITEiPS01271. NA_SULFATE. 1 hit.
PS51202. RCK_C. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYFBS_ECOLI
AccessioniPrimary (citable) accession number: P0AFU2
Secondary accession number(s): P76935, P77741
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 16, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.