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Protein

Inner membrane ABC transporter permease protein YejB

Gene

yejB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

  • microcin transport Source: EcoCyc
  • transmembrane transport Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YEJB-MONOMER.
ECOL316407:JW2166-MONOMER.
RETL1328306-WGS:GSTH-184-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane ABC transporter permease protein YejB
Gene namesi
Name:yejB
Ordered Locus Names:b2178, JW2166
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12038. yejB.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 88PeriplasmicSequence analysis
Transmembranei9 – 2921HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini30 – 378CytoplasmicSequence analysis
Transmembranei38 – 5821HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini59 – 13577PeriplasmicSequence analysisAdd
BLAST
Transmembranei136 – 15621HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini157 – 17216CytoplasmicSequence analysisAdd
BLAST
Transmembranei173 – 19321HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini194 – 22431PeriplasmicSequence analysisAdd
BLAST
Transmembranei225 – 24521HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini246 – 28439CytoplasmicSequence analysisAdd
BLAST
Transmembranei285 – 30521HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini306 – 32621PeriplasmicSequence analysisAdd
BLAST
Transmembranei327 – 34721HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini348 – 36417CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • ATP-binding cassette (ABC) transporter complex Source: EcoCyc
  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 364364Inner membrane ABC transporter permease protein YejBPRO_0000060257Add
BLAST

Proteomic databases

PaxDbiP0AFU0.

Interactioni

Protein-protein interaction databases

BioGridi4259360. 5 interactions.
STRINGi511145.b2178.

Structurei

3D structure databases

ProteinModelPortaliP0AFU0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini133 – 348216ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108I5X. Bacteria.
COG4174. LUCA.
HOGENOMiHOG000170244.
InParanoidiP0AFU0.
KOiK13894.
OMAiVRFDFGN.
OrthoDBiEOG66F098.
PhylomeDBiP0AFU0.

Family and domain databases

Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAYLIRRLL LVIPTLWAII TINFFIVQIA PGGPVDQAIA AIEFGNAGVL
60 70 80 90 100
PGAGGEGVRA SHAQTGVGNI SDSNYRGGRG LDPEVIAEIT HRYGFDKPIH
110 120 130 140 150
ERYFKMLWDY IRFDFGDSLF RSASVLTLIK DSLPVSITLG LWSTLIIYLV
160 170 180 190 200
SIPLGIRKAV YNGSRFDVWS SAFIIIGYAI PAFLFAILLI VFFAGGSYFD
210 220 230 240 250
LFPLRGLVSA NFDSLPWYQK ITDYLWHITL PVLATVIGGF AALTMLTKNS
260 270 280 290 300
FLDEVRKQYV VTARAKGVSE KNILWKHVFR NAMLLVIAGF PATFISMFFT
310 320 330 340 350
GSLLIEVMFS LNGLGLLGYE ATVSRDYPVM FGTLYIFTLI GLLLNIVSDI
360
SYTLVDPRID FEGR
Length:364
Mass (Da):40,360
Last modified:December 20, 2005 - v1
Checksum:i03AA6A7EC1F808AC
GO

Sequence cautioni

The sequence AAA16376.1 differs from that shown. Reason: Frameshift at position 126. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00008 Genomic DNA. Translation: AAA16376.1. Frameshift.
U00096 Genomic DNA. Translation: AAC75239.1.
AP009048 Genomic DNA. Translation: BAA15986.1.
PIRiA64987.
RefSeqiNP_416683.1. NC_000913.3.
WP_000501604.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75239; AAC75239; b2178.
BAA15986; BAA15986; BAA15986.
GeneIDi946679.
KEGGiecj:JW2166.
eco:b2178.
PATRICi32119711. VBIEscCol129921_2266.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00008 Genomic DNA. Translation: AAA16376.1. Frameshift.
U00096 Genomic DNA. Translation: AAC75239.1.
AP009048 Genomic DNA. Translation: BAA15986.1.
PIRiA64987.
RefSeqiNP_416683.1. NC_000913.3.
WP_000501604.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFU0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259360. 5 interactions.
STRINGi511145.b2178.

Proteomic databases

PaxDbiP0AFU0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75239; AAC75239; b2178.
BAA15986; BAA15986; BAA15986.
GeneIDi946679.
KEGGiecj:JW2166.
eco:b2178.
PATRICi32119711. VBIEscCol129921_2266.

Organism-specific databases

EchoBASEiEB1973.
EcoGeneiEG12038. yejB.

Phylogenomic databases

eggNOGiENOG4108I5X. Bacteria.
COG4174. LUCA.
HOGENOMiHOG000170244.
InParanoidiP0AFU0.
KOiK13894.
OMAiVRFDFGN.
OrthoDBiEOG66F098.
PhylomeDBiP0AFU0.

Enzyme and pathway databases

BioCyciEcoCyc:YEJB-MONOMER.
ECOL316407:JW2166-MONOMER.
RETL1328306-WGS:GSTH-184-MONOMER.

Miscellaneous databases

PROiP0AFU0.

Family and domain databases

Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Automated multiplex sequencing of the E.coli genome."
    Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K., Church G.M.
    Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / BHB2600.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYEJB_ECOLI
AccessioniPrimary (citable) accession number: P0AFU0
Secondary accession number(s): P33914, P76448
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 20, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.