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Protein

UPF0118 inner membrane protein YdiK

Gene

ydiK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G6914-MONOMER.
ECOL316407:JW1678-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0118 inner membrane protein YdiK
Gene namesi
Name:ydiK
Ordered Locus Names:b1688, JW1678
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13970. ydiK.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1717PeriplasmicSequence analysisAdd
BLAST
Transmembranei18 – 3821HelicalSequence analysisAdd
BLAST
Topological domaini39 – 391CytoplasmicSequence analysis
Transmembranei40 – 6021HelicalSequence analysisAdd
BLAST
Topological domaini61 – 655PeriplasmicSequence analysis
Transmembranei66 – 8621HelicalSequence analysisAdd
BLAST
Topological domaini87 – 10620CytoplasmicSequence analysisAdd
BLAST
Transmembranei107 – 12721HelicalSequence analysisAdd
BLAST
Topological domaini128 – 15629PeriplasmicSequence analysisAdd
BLAST
Transmembranei157 – 17721HelicalSequence analysisAdd
BLAST
Topological domaini178 – 21336CytoplasmicSequence analysisAdd
BLAST
Transmembranei214 – 23421HelicalSequence analysisAdd
BLAST
Topological domaini235 – 24814PeriplasmicSequence analysisAdd
BLAST
Transmembranei249 – 26921HelicalSequence analysisAdd
BLAST
Topological domaini270 – 2745CytoplasmicSequence analysis
Transmembranei275 – 29521HelicalSequence analysisAdd
BLAST
Topological domaini296 – 30813PeriplasmicSequence analysisAdd
BLAST
Transmembranei309 – 32921HelicalSequence analysisAdd
BLAST
Topological domaini330 – 37041CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 370370UPF0118 inner membrane protein YdiKPRO_0000148299Add
BLAST

Proteomic databases

PaxDbiP0AFS7.

Interactioni

Protein-protein interaction databases

BioGridi4259460. 15 interactions.
STRINGi511145.b1688.

Structurei

3D structure databases

ProteinModelPortaliP0AFS7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0118 (PerM) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105IPI. Bacteria.
COG0628. LUCA.
HOGENOMiHOG000181764.
InParanoidiP0AFS7.
OMAiGFNLADH.
OrthoDBiEOG6MD921.
PhylomeDBiP0AFS7.

Family and domain databases

InterProiIPR002549. AI-2E-like.
[Graphical view]
PANTHERiPTHR21716. PTHR21716. 1 hit.
PfamiPF01594. UPF0118. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNVRQPRDV AQILLSVLFL AIMIVACLWI VQPFILGFAW AGTVVIATWP
60 70 80 90 100
VLLRLQKIMF GRRSLAVLVM TLLLVMVFII PIALLVNSIV DGSGPLIKAI
110 120 130 140 150
SSGDMTLPDL AWLNTIPVIG AKLYAGWHNL LDMGGTAIMA KVRPYIGTTT
160 170 180 190 200
TWFVGQAAHI GRFMVHCALM LLFSALLYWR GEQVAQGIRH FATRLAGVRG
210 220 230 240 250
DAAVLLAAQA IRAVALGVVV TALVQAVLGG IGLAVSGVPY ATLLTVLMIL
260 270 280 290 300
SCLVQLGPLP VLIPAIIWLY WTGDTTWGTV LLVWSGVVGT LDNVIRPMLI
310 320 330 340 350
RMGADLPLIL ILSGVIGGLI AFGMIGLFIG PVLLAVSWRL FAAWVEEVPP
360 370
PTDQPEEILE ELGEIEKPNK
Length:370
Mass (Da):39,841
Last modified:December 20, 2005 - v1
Checksum:i14B7AD79D8C56248
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74758.1.
AP009048 Genomic DNA. Translation: BAA15450.1.
PIRiH64926.
RefSeqiNP_416203.1. NC_000913.3.
WP_000248636.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74758; AAC74758; b1688.
BAA15450; BAA15450; BAA15450.
GeneIDi946183.
KEGGiecj:JW1678.
eco:b1688.
PATRICi32118682. VBIEscCol129921_1759.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74758.1.
AP009048 Genomic DNA. Translation: BAA15450.1.
PIRiH64926.
RefSeqiNP_416203.1. NC_000913.3.
WP_000248636.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFS7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259460. 15 interactions.
STRINGi511145.b1688.

Proteomic databases

PaxDbiP0AFS7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74758; AAC74758; b1688.
BAA15450; BAA15450; BAA15450.
GeneIDi946183.
KEGGiecj:JW1678.
eco:b1688.
PATRICi32118682. VBIEscCol129921_1759.

Organism-specific databases

EchoBASEiEB3727.
EcoGeneiEG13970. ydiK.

Phylogenomic databases

eggNOGiENOG4105IPI. Bacteria.
COG0628. LUCA.
HOGENOMiHOG000181764.
InParanoidiP0AFS7.
OMAiGFNLADH.
OrthoDBiEOG6MD921.
PhylomeDBiP0AFS7.

Enzyme and pathway databases

BioCyciEcoCyc:G6914-MONOMER.
ECOL316407:JW1678-MONOMER.

Miscellaneous databases

PROiP0AFS7.

Family and domain databases

InterProiIPR002549. AI-2E-like.
[Graphical view]
PANTHERiPTHR21716. PTHR21716. 1 hit.
PfamiPF01594. UPF0118. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYDIK_ECOLI
AccessioniPrimary (citable) accession number: P0AFS7
Secondary accession number(s): P77175
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 20, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.