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Protein

Inner membrane ABC transporter permease protein YdcV

Gene

ydcV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in natural transformation (PubMed:26826386). Probably part of the ABC transporter complex YdcSTUV. Probably responsible for the translocation of the substrate across the membrane. During natural transformation, may serve as the channel for dsDNA uptake (Probable).1 Publication1 Publication

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YDCV-MONOMER
MetaCyc:YDCV-MONOMER

Protein family/group databases

TCDBi3.A.1.11.9 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane ABC transporter permease protein YdcVCurated
Gene namesi
Name:ydcV
Ordered Locus Names:b1443, JW1438
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13765 ydcV

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 12CytoplasmicCuratedAdd BLAST12
Transmembranei13 – 33HelicalSequence analysisAdd BLAST21
Topological domaini34 – 70PeriplasmicCuratedAdd BLAST37
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Topological domaini92 – 100CytoplasmicCurated9
Transmembranei101 – 121HelicalSequence analysisAdd BLAST21
Topological domaini122 – 128PeriplasmicCurated7
Transmembranei129 – 149HelicalSequence analysisAdd BLAST21
Topological domaini150 – 189CytoplasmicCuratedAdd BLAST40
Transmembranei190 – 210HelicalSequence analysisAdd BLAST21
Topological domaini211 – 236PeriplasmicCuratedAdd BLAST26
Transmembranei237 – 257HelicalSequence analysisAdd BLAST21
Topological domaini258 – 264Cytoplasmic1 Publication7

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Natural transformation rate of the mutant is reduced by 3.3-9.5 folds. Mutation does not affect chemical transformation.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602431 – 264Inner membrane ABC transporter permease protein YdcVAdd BLAST264

Proteomic databases

PaxDbiP0AFR9
PRIDEiP0AFR9

Interactioni

Protein-protein interaction databases

BioGridi4260190, 44 interactors
STRINGi316385.ECDH10B_1573

Structurei

3D structure databases

ProteinModelPortaliP0AFR9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 252ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST188

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105NRK Bacteria
ENOG410XPIA LUCA
HOGENOMiHOG000263700
InParanoidiP0AFR9
KOiK02053
OMAiYNNVIAR
PhylomeDBiP0AFR9

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.10, 1 hit
InterProiView protein in InterPro
IPR000515 MetI-like
IPR035906 MetI-like_sf
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P0AFR9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSERAPFFL KLAAWGGVVF LHFPILIIAA YAFNTEDAAF SFPPQGLTLR
60 70 80 90 100
WFSVAAQRSD ILDAVTLSLK VAALATLIAL VLGTLAAAAL WRRDFFGKNA
110 120 130 140 150
ISLLLLLPIA LPGIVTGLAL LTAFKTINLE PGFFTIVVGH ATFCVVVVFN
160 170 180 190 200
NVIARFRRTS WSLVEASMDL GANGWQTFRY VVLPNLSSAL LAGGMLAFAL
210 220 230 240 250
SFDEIIVTTF TAGHERTLPL WLLNQLGRPR DVPVTNVVAL LVMLVTTLPI
260
LGAWWLTREG DNGQ
Length:264
Mass (Da):28,722
Last modified:December 20, 2005 - v1
Checksum:i611F6181E57DB826
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74525.1
AP009048 Genomic DNA Translation: BAA15072.1
PIRiF64896
RefSeqiNP_415960.1, NC_000913.3
WP_000555458.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74525; AAC74525; b1443
BAA15072; BAA15072; BAA15072
GeneIDi945903
KEGGiecj:JW1438
eco:b1443
PATRICifig|1411691.4.peg.825

Similar proteinsi

Entry informationi

Entry nameiYDCV_ECOLI
AccessioniPrimary (citable) accession number: P0AFR9
Secondary accession number(s): P77505
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: April 25, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health