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Protein

Putative aminoacrylate peracid reductase RutC

Gene

rutC

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei106 – 1061By similarity

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. nitrogen utilization Source: UniProtKB-HAMAP
  2. uracil catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciECOL199310:C1147-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aminoacrylate peracid reductase RutC (EC:1.-.-.-)
Gene namesi
Name:rutC
Ordered Locus Names:c1147
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001410: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 128128Putative aminoacrylate peracid reductase RutCPRO_0000402382Add
BLAST

Expressioni

Inductioni

Up-regulated by the nitrogen regulatory protein C (NtrC also called GlnG) and repressed by RutR.Curated

Interactioni

Subunit structurei

Homotrimer.By similarity

Protein-protein interaction databases

STRINGi199310.c1147.

Structurei

Secondary structure

1
128
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 63Combined sources
Beta strandi20 – 245Combined sources
Beta strandi27 – 337Combined sources
Beta strandi42 – 443Combined sources
Helixi48 – 6518Combined sources
Helixi70 – 723Combined sources
Beta strandi73 – 819Combined sources
Helixi83 – 853Combined sources
Helixi86 – 9611Combined sources
Beta strandi103 – 1086Combined sources
Beta strandi118 – 1258Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3V4DX-ray1.95A/B/C/D/E/F1-128[»]
ProteinModelPortaliP0AFQ6.
SMRiP0AFQ6. Positions 1-128.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RutC family.Curated

Phylogenomic databases

HOGENOMiHOG000267215.
KOiK09021.
OMAiTIITPPG.
OrthoDBiEOG6QVRPF.

Family and domain databases

Gene3Di3.30.1330.40. 1 hit.
HAMAPiMF_00831. RutC.
InterProiIPR013813. Endoribo_LPSP/chorism_mut-like.
IPR019898. RutC.
IPR019897. YjgF-like_CS.
IPR006175. YjgF/Yer057p/UK114.
[Graphical view]
PANTHERiPTHR11803. PTHR11803. 1 hit.
PfamiPF01042. Ribonuc_L-PSP. 1 hit.
[Graphical view]
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR03610. RutC. 1 hit.
PROSITEiPS01094. UPF0076. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFQ6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPKSVIIPAG SSAPLAPFVP GTLADGVVYV SGTLAFDQHN NVLFADDPKA
60 70 80 90 100
QTRHVLETIR KVIETAGGTM ADVTFNSIFI TDWKNYAAIN EIYAEFFPGD
110 120
KPARFCIQCG LVKPDALVEI ATIAHIAK
Length:128
Mass (Da):13,763
Last modified:December 20, 2005 - v1
Checksum:i7D5FC2374597D907
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN79615.1.
RefSeqiNP_753072.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN79615; AAN79615; c1147.
GeneIDi1039370.
KEGGiecc:c1147.
PATRICi18280320. VBIEscCol75197_1087.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN79615.1.
RefSeqiNP_753072.1. NC_004431.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3V4DX-ray1.95A/B/C/D/E/F1-128[»]
ProteinModelPortaliP0AFQ6.
SMRiP0AFQ6. Positions 1-128.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi199310.c1147.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN79615; AAN79615; c1147.
GeneIDi1039370.
KEGGiecc:c1147.
PATRICi18280320. VBIEscCol75197_1087.

Phylogenomic databases

HOGENOMiHOG000267215.
KOiK09021.
OMAiTIITPPG.
OrthoDBiEOG6QVRPF.

Enzyme and pathway databases

BioCyciECOL199310:C1147-MONOMER.

Family and domain databases

Gene3Di3.30.1330.40. 1 hit.
HAMAPiMF_00831. RutC.
InterProiIPR013813. Endoribo_LPSP/chorism_mut-like.
IPR019898. RutC.
IPR019897. YjgF-like_CS.
IPR006175. YjgF/Yer057p/UK114.
[Graphical view]
PANTHERiPTHR11803. PTHR11803. 1 hit.
PfamiPF01042. Ribonuc_L-PSP. 1 hit.
[Graphical view]
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR03610. RutC. 1 hit.
PROSITEiPS01094. UPF0076. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFT073 / ATCC 700928 / UPEC.

Entry informationi

Entry nameiRUTC_ECOL6
AccessioniPrimary (citable) accession number: P0AFQ6
Secondary accession number(s): P75896
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 7, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.