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Protein

Inner membrane transport permease YbhS

Gene

ybhS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • efflux transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • drug transmembrane transport Source: EcoCyc

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YBHS-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane transport permease YbhS
Gene namesi
Name:ybhS
Ordered Locus Names:b0793, JW0777
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13675. ybhS.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 28PeriplasmicSequence analysisAdd BLAST28
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21
Topological domaini50 – 181CytoplasmicSequence analysisAdd BLAST132
Transmembranei182 – 202HelicalSequence analysisAdd BLAST21
Topological domaini203 – 234PeriplasmicSequence analysisAdd BLAST32
Transmembranei235 – 255HelicalSequence analysisAdd BLAST21
Topological domaini256 – 261CytoplasmicSequence analysis6
Transmembranei262 – 282HelicalSequence analysisAdd BLAST21
Topological domaini283 – 291PeriplasmicSequence analysis9
Transmembranei292 – 312HelicalSequence analysisAdd BLAST21
Topological domaini313 – 322CytoplasmicSequence analysis10
Transmembranei323 – 343HelicalSequence analysisAdd BLAST21
Topological domaini344 – 345PeriplasmicSequence analysis2
Transmembranei346 – 366HelicalSequence analysisAdd BLAST21
Topological domaini367 – 377CytoplasmicSequence analysisAdd BLAST11

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001830051 – 377Inner membrane transport permease YbhSAdd BLAST377

Proteomic databases

PaxDbiP0AFQ2.
PRIDEiP0AFQ2.

Interactioni

Protein-protein interaction databases

BioGridi4261835. 7 interactors.
IntActiP0AFQ2. 5 interactors.
STRINGi316385.ECDH10B_0861.

Structurei

3D structure databases

ProteinModelPortaliP0AFQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini145 – 375ABC transmembrane type-2PROSITE-ProRule annotationAdd BLAST231

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QWP. Bacteria.
COG0842. LUCA.
HOGENOMiHOG000270977.
InParanoidiP0AFQ2.
KOiK01992.
PhylomeDBiP0AFQ2.

Family and domain databases

InterProiView protein in InterPro
IPR000412. ABC_2_transport.
PROSITEiView protein in PROSITE
PS51012. ABC_TM2. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AFQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNPILSWRR VRALCVKETR QIVRDPSSWL IAVVIPLLLL FIFGYGINLD
60 70 80 90 100
SSKLRVGILL EQRSEAALDF THTMTGSPYI DATISDNRQE LIAKMQAGKI
110 120 130 140 150
RGLVVIPVDF AEQMERANAT APIQVITDGS EPNTANFVQG YVEGIWQIWQ
160 170 180 190 200
MQRAEDNGQT FEPLIDVQTR YWFNPAAISQ HFIIPGAVTI IMTVIGAILT
210 220 230 240 250
SLVVAREWER GTMEALLSTE ITRTELLLCK LIPYYFLGML AMLLCMLVSV
260 270 280 290 300
FILGVPYRGS LLILFFISSL FLLSTLGMGL LISTITRNQF NAAQVALNAA
310 320 330 340 350
FLPSIMLSGF IFQIDSMPAV IRAVTYIIPA RYFVSTLQSL FLAGNIPVVL
360 370
VVNVLFLIAS AVMFIGLTWL KTKRRLD
Length:377
Mass (Da):42,060
Last modified:December 20, 2005 - v1
Checksum:iC25E40FA4586EEFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73880.1.
AP009048 Genomic DNA. Translation: BAA35453.1.
PIRiA64816.
RefSeqiNP_415314.1. NC_000913.3.
WP_000070131.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73880; AAC73880; b0793.
BAA35453; BAA35453; BAA35453.
GeneIDi945411.
KEGGiecj:JW0777.
eco:b0793.
PATRICifig|1411691.4.peg.1485.

Similar proteinsi

Entry informationi

Entry nameiYBHS_ECOLI
AccessioniPrimary (citable) accession number: P0AFQ2
Secondary accession number(s): P75775
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: August 30, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families