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UniProtKB - P0AFQ2 (YBHS_ECOLI)

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Protein

Inner membrane transport permease YbhS

Gene

ybhS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YBHS-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane transport permease YbhS
Gene namesi
Name:ybhS
Ordered Locus Names:b0793, JW0777
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13675. ybhS.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 28PeriplasmicSequence analysisAdd BLAST28
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21
Topological domaini50 – 181CytoplasmicSequence analysisAdd BLAST132
Transmembranei182 – 202HelicalSequence analysisAdd BLAST21
Topological domaini203 – 234PeriplasmicSequence analysisAdd BLAST32
Transmembranei235 – 255HelicalSequence analysisAdd BLAST21
Topological domaini256 – 261CytoplasmicSequence analysis6
Transmembranei262 – 282HelicalSequence analysisAdd BLAST21
Topological domaini283 – 291PeriplasmicSequence analysis9
Transmembranei292 – 312HelicalSequence analysisAdd BLAST21
Topological domaini313 – 322CytoplasmicSequence analysis10
Transmembranei323 – 343HelicalSequence analysisAdd BLAST21
Topological domaini344 – 345PeriplasmicSequence analysis2
Transmembranei346 – 366HelicalSequence analysisAdd BLAST21
Topological domaini367 – 377CytoplasmicSequence analysisAdd BLAST11

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001830051 – 377Inner membrane transport permease YbhSAdd BLAST377

Proteomic databases

PaxDbiP0AFQ2.
PRIDEiP0AFQ2.

Interactioni

Protein-protein interaction databases

BioGridi4261835. 7 interactors.
IntActiP0AFQ2. 5 interactors.
STRINGi316385.ECDH10B_0861.

Structurei

3D structure databases

ProteinModelPortaliP0AFQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini145 – 375ABC transmembrane type-2PROSITE-ProRule annotationAdd BLAST231

Sequence similaritiesi

Belongs to the ABC-2 integral membrane protein family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QWP. Bacteria.
COG0842. LUCA.
HOGENOMiHOG000270977.
InParanoidiP0AFQ2.
KOiK01992.
PhylomeDBiP0AFQ2.

Family and domain databases

InterProiView protein in InterPro
IPR000412. ABC_2_transport.
PROSITEiView protein in PROSITE
PS51012. ABC_TM2. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AFQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNPILSWRR VRALCVKETR QIVRDPSSWL IAVVIPLLLL FIFGYGINLD 
        60         70         80         90        100
SSKLRVGILL EQRSEAALDF THTMTGSPYI DATISDNRQE LIAKMQAGKI 
       110        120        130        140        150
RGLVVIPVDF AEQMERANAT APIQVITDGS EPNTANFVQG YVEGIWQIWQ 
       160        170        180        190        200
MQRAEDNGQT FEPLIDVQTR YWFNPAAISQ HFIIPGAVTI IMTVIGAILT 
       210        220        230        240        250
SLVVAREWER GTMEALLSTE ITRTELLLCK LIPYYFLGML AMLLCMLVSV 
       260        270        280        290        300
FILGVPYRGS LLILFFISSL FLLSTLGMGL LISTITRNQF NAAQVALNAA 
       310        320        330        340        350
FLPSIMLSGF IFQIDSMPAV IRAVTYIIPA RYFVSTLQSL FLAGNIPVVL 
       360        370 
VVNVLFLIAS AVMFIGLTWL KTKRRLD
Length:377
Mass (Da):42,060
Last modified:December 20, 2005 - v1
Checksum:iC25E40FA4586EEFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73880.1.
AP009048 Genomic DNA. Translation: BAA35453.1.
PIRiA64816.
RefSeqiNP_415314.1. NC_000913.3.
WP_000070131.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73880; AAC73880; b0793.
BAA35453; BAA35453; BAA35453.
GeneIDi945411.
KEGGiecj:JW0777.
eco:b0793.
PATRICifig|1411691.4.peg.1485.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiYBHS_ECOLI
AccessioniPrimary (citable) accession number: P0AFQ2
Secondary accession number(s): P75775
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: July 5, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families