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Protein

Uncharacterized oxidoreductase YbbO

Gene

ybbO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei146 – 1461SubstrateBy similarity
Active sitei159 – 1591Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 4127NAD or NADPBy similarityAdd
BLAST

GO - Molecular functioni

  • alcohol dehydrogenase (NADP+) activity Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:G6269-MONOMER.
ECOL316407:JW0482-MONOMER.
RETL1328306-WGS:GSTH-3867-MONOMER.
RETL1328306-WGS:GSTH-923-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YbbO (EC:1.-.-.-)
Gene namesi
Name:ybbO
Ordered Locus Names:b0493, JW0482
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13262. ybbO.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Uncharacterized oxidoreductase YbbOPRO_0000054822Add
BLAST

Proteomic databases

PaxDbiP0AFP4.
PRIDEiP0AFP4.

Interactioni

Protein-protein interaction databases

BioGridi4260670. 6 interactions.
DIPiDIP-48139N.
IntActiP0AFP4. 9 interactions.
STRINGi511145.b0493.

Structurei

3D structure databases

ProteinModelPortaliP0AFP4.
SMRiP0AFP4. Positions 9-232.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105E1F. Bacteria.
COG1028. LUCA.
InParanoidiP0AFP4.
OMAiAPGRIVM.
OrthoDBiEOG6N3CR8.
PhylomeDBiP0AFP4.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHKATEILT GKVMQKSVLI TGCSSGIGLE SALELKRQGF HVLAGCRKPD
60 70 80 90 100
DVERMNSMGF TGVLIDLDSP ESVDRAADEV IALTDNCLYG IFNNAGFGMY
110 120 130 140 150
GPLSTISRAQ MEQQFSANFF GAHQLTMRLL PAMLPHGEGR IVMTSSVMGL
160 170 180 190 200
ISTPGRGAYA ASKYALEAWS DALRMELRHS GIKVSLIEPG PIRTRFTDNV
210 220 230 240 250
NQTQSDKPVE NPGIAARFTL GPEAVVDKVR HAFISEKPKM RYPVTLVTWA
260
VMVLKRLLPG RVMDKILQG
Length:269
Mass (Da):29,410
Last modified:December 20, 2005 - v1
Checksum:i3EFC0E423AE89D87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82664 Genomic DNA. Translation: AAB40247.1.
U00096 Genomic DNA. Translation: AAC73595.1.
AP009048 Genomic DNA. Translation: BAE76272.1.
PIRiD64780.
RefSeqiNP_415026.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC73595; AAC73595; b0493.
BAE76272; BAE76272; BAE76272.
GeneIDi945337.
KEGGiecj:JW0482.
eco:b0493.
PATRICi32116145. VBIEscCol129921_0514.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82664 Genomic DNA. Translation: AAB40247.1.
U00096 Genomic DNA. Translation: AAC73595.1.
AP009048 Genomic DNA. Translation: BAE76272.1.
PIRiD64780.
RefSeqiNP_415026.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP0AFP4.
SMRiP0AFP4. Positions 9-232.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260670. 6 interactions.
DIPiDIP-48139N.
IntActiP0AFP4. 9 interactions.
STRINGi511145.b0493.

Proteomic databases

PaxDbiP0AFP4.
PRIDEiP0AFP4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73595; AAC73595; b0493.
BAE76272; BAE76272; BAE76272.
GeneIDi945337.
KEGGiecj:JW0482.
eco:b0493.
PATRICi32116145. VBIEscCol129921_0514.

Organism-specific databases

EchoBASEiEB3050.
EcoGeneiEG13262. ybbO.

Phylogenomic databases

eggNOGiENOG4105E1F. Bacteria.
COG1028. LUCA.
InParanoidiP0AFP4.
OMAiAPGRIVM.
OrthoDBiEOG6N3CR8.
PhylomeDBiP0AFP4.

Enzyme and pathway databases

BioCyciEcoCyc:G6269-MONOMER.
ECOL316407:JW0482-MONOMER.
RETL1328306-WGS:GSTH-3867-MONOMER.
RETL1328306-WGS:GSTH-923-MONOMER.

Miscellaneous databases

PROiP0AFP4.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYBBO_ECOLI
AccessioniPrimary (citable) accession number: P0AFP4
Secondary accession number(s): P77388, Q2MBT4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: June 8, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.