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Protein

UPF0126 inner membrane protein YadS

Gene

yadS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG12333-MONOMER.
ECOL316407:JW0153-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0126 inner membrane protein YadS
Gene namesi
Name:yadS
Ordered Locus Names:b0157, JW0153
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12333. yadS.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalSequence analysisAdd
BLAST
Topological domaini22 – 298CytoplasmicSequence analysis
Transmembranei30 – 5021HelicalSequence analysisAdd
BLAST
Topological domaini51 – 588PeriplasmicSequence analysis
Transmembranei59 – 7921HelicalSequence analysisAdd
BLAST
Topological domaini80 – 856CytoplasmicSequence analysis
Transmembranei86 – 10621HelicalSequence analysisAdd
BLAST
Topological domaini107 – 1126PeriplasmicSequence analysis
Transmembranei113 – 13321HelicalSequence analysisAdd
BLAST
Topological domaini134 – 14815CytoplasmicSequence analysisAdd
BLAST
Transmembranei149 – 16921HelicalSequence analysisAdd
BLAST
Topological domaini170 – 1701PeriplasmicSequence analysis
Transmembranei171 – 19121HelicalSequence analysisAdd
BLAST
Topological domaini192 – 20716CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 207207UPF0126 inner membrane protein YadSPRO_0000166297Add
BLAST

Proteomic databases

PaxDbiP0AFP0.

Interactioni

Protein-protein interaction databases

BioGridi4261385. 14 interactions.
STRINGi511145.b0157.

Structurei

3D structure databases

ProteinModelPortaliP0AFP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0126 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EN6. Bacteria.
COG2860. LUCA.
HOGENOMiHOG000218258.
InParanoidiP0AFP0.
OMAiTYLWVIF.
OrthoDBiEOG6WMJ34.
PhylomeDBiP0AFP0.

Family and domain databases

InterProiIPR005115. UPF0126.
[Graphical view]
PfamiPF03458. UPF0126. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVYWLDIVG TAVFAISGVL LAGKLRMDPF GVLVLGVVTA VGGGTIRDMA
60 70 80 90 100
LDHGPVFWVK DPTDLVVAMV TSMLTIVLVR QPRRLPKWML PVLDAVGLAV
110 120 130 140 150
FVGIGVNKAF NAEAGPLIAV CMGVITGVGG GIIRDVLARE IPMILRTEIY
160 170 180 190 200
ATACIIGGIV HATAYYTFSV PLETASMMGM VVTLLIRLAA IRWHLKLPTF

ALDENGR
Length:207
Mass (Da):22,128
Last modified:December 20, 2005 - v1
Checksum:iC54E17DBF4C3D058
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70214 Genomic DNA. Translation: AAB08587.1.
U00096 Genomic DNA. Translation: AAC73268.1.
AP009048 Genomic DNA. Translation: BAB96734.1.
PIRiS45226.
RefSeqiNP_414699.1. NC_000913.3.
WP_000964221.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73268; AAC73268; b0157.
BAB96734; BAB96734; BAB96734.
GeneIDi949062.
KEGGiecj:JW0153.
eco:b0157.
PATRICi32115423. VBIEscCol129921_0163.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70214 Genomic DNA. Translation: AAB08587.1.
U00096 Genomic DNA. Translation: AAC73268.1.
AP009048 Genomic DNA. Translation: BAB96734.1.
PIRiS45226.
RefSeqiNP_414699.1. NC_000913.3.
WP_000964221.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFP0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261385. 14 interactions.
STRINGi511145.b0157.

Proteomic databases

PaxDbiP0AFP0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73268; AAC73268; b0157.
BAB96734; BAB96734; BAB96734.
GeneIDi949062.
KEGGiecj:JW0153.
eco:b0157.
PATRICi32115423. VBIEscCol129921_0163.

Organism-specific databases

EchoBASEiEB2237.
EcoGeneiEG12333. yadS.

Phylogenomic databases

eggNOGiENOG4105EN6. Bacteria.
COG2860. LUCA.
HOGENOMiHOG000218258.
InParanoidiP0AFP0.
OMAiTYLWVIF.
OrthoDBiEOG6WMJ34.
PhylomeDBiP0AFP0.

Enzyme and pathway databases

BioCyciEcoCyc:EG12333-MONOMER.
ECOL316407:JW0153-MONOMER.

Miscellaneous databases

PROiP0AFP0.

Family and domain databases

InterProiIPR005115. UPF0126.
[Graphical view]
PfamiPF03458. UPF0126. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region."
    Fujita N., Mori H., Yura T., Ishihama A.
    Nucleic Acids Res. 22:1637-1639(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYADS_ECOLI
AccessioniPrimary (citable) accession number: P0AFP0
Secondary accession number(s): P37027
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 20, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.