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Protein

Inner membrane transport permease YadH

Gene

yadH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YADH-MONOMER

Protein family/group databases

TCDBi3.A.1.105.17 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane transport permease YadH
Gene namesi
Name:yadH
Ordered Locus Names:b0128, JW0124
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12321 yadH

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 22PeriplasmicSequence analysisAdd BLAST22
Transmembranei23 – 43HelicalSequence analysisAdd BLAST21
Topological domaini44 – 52CytoplasmicSequence analysis9
Transmembranei53 – 73HelicalSequence analysisAdd BLAST21
Topological domaini74 – 94PeriplasmicSequence analysisAdd BLAST21
Transmembranei95 – 115HelicalSequence analysisAdd BLAST21
Topological domaini116CytoplasmicSequence analysis1
Transmembranei117 – 137HelicalSequence analysisAdd BLAST21
Topological domaini138PeriplasmicSequence analysis1
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 169CytoplasmicSequence analysis10
Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
Topological domaini191 – 223PeriplasmicSequence analysisAdd BLAST33
Transmembranei224 – 244HelicalSequence analysisAdd BLAST21
Topological domaini245 – 256CytoplasmicSequence analysisAdd BLAST12

GO - Cellular componenti

  • ATP-binding cassette (ABC) transporter complex Source: InterPro
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001829981 – 256Inner membrane transport permease YadHAdd BLAST256

Proteomic databases

PaxDbiP0AFN6
PRIDEiP0AFN6

Interactioni

Protein-protein interaction databases

BioGridi4259734, 47 interactors
STRINGi316385.ECDH10B_0108

Structurei

3D structure databases

ProteinModelPortaliP0AFN6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 251ABC transmembrane type-2PROSITE-ProRule annotationAdd BLAST230

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E3A Bacteria
COG0842 LUCA
HOGENOMiHOG000252768
InParanoidiP0AFN6
KOiK01992
OMAiRYGFFGV
PhylomeDBiP0AFN6

Family and domain databases

InterProiView protein in InterPro
IPR013525 ABC_2_trans
IPR000412 ABC_2_transport
PfamiView protein in Pfam
PF01061 ABC2_membrane, 1 hit
PIRSFiPIRSF006648 DrrB, 1 hit
PRINTSiPR00164 ABC2TRNSPORT
PROSITEiView protein in PROSITE
PS51012 ABC_TM2, 1 hit

Sequencei

Sequence statusi: Complete.

P0AFN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMHLYWVALK SIWAKEIHRF MRIWVQTLVP PVITMTLYFI IFGNLIGSRI
60 70 80 90 100
GDMHGFSYMQ FIVPGLIMMS VITNAYANVA SSFFGAKFQR NIEELLVAPV
110 120 130 140 150
PTHVIIAGYV GGGVARGLFV GILVTAISLF FVPFQVHSWV FVALTLVLTA
160 170 180 190 200
VLFSLAGLLN GVFAKTFDDI SLVPTFVLTP LTYLGGVFYS LTLLPPFWQG
210 220 230 240 250
LSHLNPIVYM ISGFRYGFLG INDVPLVTTF GVLVVFIVAF YLICWSLIQR

GRGLRS
Length:256
Mass (Da):28,516
Last modified:December 20, 2005 - v1
Checksum:i2AE10E6CB143F708
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti214F → L (PubMed:9278503).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC73239.1
AP009048 Genomic DNA Translation: BAB96705.2
PIRiH64735
RefSeqiNP_414670.1, NC_000913.3
WP_000972203.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73239; AAC73239; b0128
BAB96705; BAB96705; BAB96705
GeneIDi944836
KEGGiecj:JW0124
eco:b0128
PATRICifig|1411691.4.peg.2154

Similar proteinsi

Entry informationi

Entry nameiYADH_ECOLI
AccessioniPrimary (citable) accession number: P0AFN6
Secondary accession number(s): P36880, P75657, Q8KMY9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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