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Protein

Phage shock protein C

Gene

pspC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspC is involved in transcription regulation.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Stress response, Transcription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG10778-MONOMER.
ECOL316407:JW1299-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phage shock protein C
Gene namesi
Name:pspC
Ordered Locus Names:b1306, JW1299
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10778. pspC.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei39 – 5921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 119119Phage shock protein CPRO_0000097074Add
BLAST

Proteomic databases

EPDiP0AFN2.
PaxDbiP0AFN2.
PRIDEiP0AFN2.

Expressioni

Inductioni

By heat, ethanol, osmotic shock and infection by filamentous bacteriophages.1 Publication

Interactioni

Subunit structurei

Interacts with PspA.1 Publication

Protein-protein interaction databases

BioGridi4263228. 428 interactions.
DIPiDIP-48215N.
IntActiP0AFN2. 3 interactions.
STRINGi511145.b1306.

Structurei

3D structure databases

ProteinModelPortaliP0AFN2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phageshock PspC family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105FM1. Bacteria.
COG1983. LUCA.
HOGENOMiHOG000276525.
KOiK03973.
OMAiMEAYVTS.
OrthoDBiEOG6W9X4M.

Family and domain databases

InterProiIPR014320. Phageshock_PspC.
IPR007168. Phageshock_PspC_N.
[Graphical view]
PfamiPF04024. PspC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02978. phageshock_pspC. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AFN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGINLNKKL WRIPQQGMVR GVCAGIANYF DVPVKLVRIL VVLSIFFGLA
60 70 80 90 100
LFTLVAYIIL SFALDPMPDN MAFGEQLPSS SELLDEVDRE LAASETRLRE
110
MERYVTSDTF TLRSRFRQL
Length:119
Mass (Da):13,517
Last modified:December 20, 2005 - v1
Checksum:iF63BED3EC5EDEE90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57560 Genomic DNA. Translation: CAA40791.1.
U00096 Genomic DNA. Translation: AAC74388.1.
AP009048 Genomic DNA. Translation: BAA14875.1.
PIRiS17123.
RefSeqiNP_415822.1. NC_000913.3.
WP_000907387.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74388; AAC74388; b1306.
BAA14875; BAA14875; BAA14875.
GeneIDi945499.
KEGGiecj:JW1299.
eco:b1306.
PATRICi32117884. VBIEscCol129921_1362.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57560 Genomic DNA. Translation: CAA40791.1.
U00096 Genomic DNA. Translation: AAC74388.1.
AP009048 Genomic DNA. Translation: BAA14875.1.
PIRiS17123.
RefSeqiNP_415822.1. NC_000913.3.
WP_000907387.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFN2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263228. 428 interactions.
DIPiDIP-48215N.
IntActiP0AFN2. 3 interactions.
STRINGi511145.b1306.

Proteomic databases

EPDiP0AFN2.
PaxDbiP0AFN2.
PRIDEiP0AFN2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74388; AAC74388; b1306.
BAA14875; BAA14875; BAA14875.
GeneIDi945499.
KEGGiecj:JW1299.
eco:b1306.
PATRICi32117884. VBIEscCol129921_1362.

Organism-specific databases

EchoBASEiEB0771.
EcoGeneiEG10778. pspC.

Phylogenomic databases

eggNOGiENOG4105FM1. Bacteria.
COG1983. LUCA.
HOGENOMiHOG000276525.
KOiK03973.
OMAiMEAYVTS.
OrthoDBiEOG6W9X4M.

Enzyme and pathway databases

BioCyciEcoCyc:EG10778-MONOMER.
ECOL316407:JW1299-MONOMER.

Miscellaneous databases

PROiP0AFN2.

Family and domain databases

InterProiIPR014320. Phageshock_PspC.
IPR007168. Phageshock_PspC_N.
[Graphical view]
PfamiPF04024. PspC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02978. phageshock_pspC. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization and sequence of the Escherichia coli stress-induced psp operon."
    Brissette J.L., Weiner L., Ripmaster T.L., Model P.
    J. Mol. Biol. 220:35-48(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, INDUCTION.
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Interactions between phage-shock proteins in Escherichia coli."
    Adams H., Teertstra W., Demmers J., Boesten R., Tommassen J.
    J. Bacteriol. 185:1174-1180(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH PSPA.
    Strain: K12.

Entry informationi

Entry nameiPSPC_ECOLI
AccessioniPrimary (citable) accession number: P0AFN2
Secondary accession number(s): P23855
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 16, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.