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Protein

Intermembrane transport protein PqiA

Gene

pqiA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of a transport pathway that contributes to membrane integrity.1 Publication

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:G6490-MONOMER

Protein family/group databases

TCDBi9.A.69.1.1 the intermembrane phospholipid translocase (impl-t) family

Names & Taxonomyi

Protein namesi
Recommended name:
Intermembrane transport protein PqiACurated
Alternative name(s):
Paraquat-inducible protein A
Gene namesi
Name:pqiA1 Publication
Synonyms:pqi5A1 Publication
Ordered Locus Names:b0950, JW0933
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12965 pqiA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 50Cytoplasmic1 PublicationAdd BLAST50
Transmembranei51 – 71HelicalSequence analysisAdd BLAST21
Topological domaini72 – 101Periplasmic1 PublicationAdd BLAST30
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Topological domaini123 – 256Cytoplasmic1 PublicationAdd BLAST134
Transmembranei257 – 277HelicalSequence analysisAdd BLAST21
Topological domaini278 – 284Periplasmic1 Publication7
Transmembranei285 – 305HelicalSequence analysisAdd BLAST21
Topological domaini306 – 346Cytoplasmic1 PublicationAdd BLAST41
Transmembranei347 – 367HelicalSequence analysisAdd BLAST21
Topological domaini368 – 370Periplasmic1 Publication3
Transmembranei371 – 391HelicalSequence analysisAdd BLAST21
Topological domaini392 – 417Cytoplasmic1 PublicationAdd BLAST26

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000585541 – 417Intermembrane transport protein PqiAAdd BLAST417

Proteomic databases

PaxDbiP0AFL9
PRIDEiP0AFL9

Expressioni

Inductioni

By paraquat.1 Publication

Interactioni

Subunit structurei

May form a complex composed of PqiA, PqiB and PqiC.1 Publication

Protein-protein interaction databases

BioGridi4260027, 13 interactors
IntActiP0AFL9, 2 interactors
STRINGi316385.ECDH10B_1020

Structurei

3D structure databases

ProteinModelPortaliP0AFL9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PqiA family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105F1S Bacteria
COG2995 LUCA
HOGENOMiHOG000283618
InParanoidiP0AFL9
KOiK03808
OMAiGNCRDEA
PhylomeDBiP0AFL9

Family and domain databases

InterProiView protein in InterPro
IPR005219 CHP00155
IPR007498 PqiA
PfamiView protein in Pfam
PF04403 PqiA, 2 hits
TIGRFAMsiTIGR00155 pqiA_fam, 1 hit

Sequencei

Sequence statusi: Complete.

P0AFL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCEHHHAAKH ILCSQCDMLV ALPRLEHGQK AACPRCGTTL TVAWDAPRQR
60 70 80 90 100
PTAYALAALF MLLLSNLFPF VNMNVAGVTS EITLLEIPGV LFSEDYASLG
110 120 130 140 150
TFFLLFVQLV PAFCLITILL LVNRAELPVR LKEQLARVLF QLKTWGMAEI
160 170 180 190 200
FLAGVLVSFV KLMAYGSIGV GSSFLPWCLF CVLQLRAFQC VDRRWLWDDI
210 220 230 240 250
APMPELRQPL KPGVTGIRQG LRSCSCCTAI LPADEPVCPR CSTKGYVRRR
260 270 280 290 300
NSLQWTLALL VTSIMLYLPA NILPIMVTDL LGSKMPSTIL AGVILLWSEG
310 320 330 340 350
SYPVAAVIFL ASIMVPTLKM IAIAWLCWDA KGHGKRDSER MHLIYEVVEF
360 370 380 390 400
VGRWSMIDVF VIAVLSALVR MGGLMSIYPA MGALMFALVV IMTMFSAMTF
410
DPRLSWDRQP ESEHEES
Length:417
Mass (Da):46,463
Last modified:December 20, 2005 - v1
Checksum:i959FD92C83F3BC8D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti338 – 417SERMH…EHEES → RKECI in CAA57256 (PubMed:7751275).CuratedAdd BLAST80

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81561 Genomic DNA Translation: CAA57256.1
U00096 Genomic DNA Translation: AAC74036.1
AP009048 Genomic DNA Translation: BAA35708.1
PIRiE64835
RefSeqiNP_415470.1, NC_000913.3
WP_000333176.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74036; AAC74036; b0950
BAA35708; BAA35708; BAA35708
GeneIDi944999
KEGGiecj:JW0933
eco:b0950
PATRICifig|1411691.4.peg.1324

Similar proteinsi

Entry informationi

Entry nameiPQIA_ECOLI
AccessioniPrimary (citable) accession number: P0AFL9
Secondary accession number(s): P43670, P77566
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: June 20, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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