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Protein

Low-affinity inorganic phosphate transporter 1

Gene

pitA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Low-affinity inorganic phosphate transport. Can also transport arsenate.

GO - Molecular functioni

  • inorganic phosphate transmembrane transporter activity Source: EcoCyc
  • solute:proton symporter activity Source: EcoCyc
  • tellurite transmembrane transporter activity Source: EcoCyc
  • zinc ion transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • phosphate ion transmembrane transport Source: EcoCyc
  • tellurite transport Source: EcoCyc

Keywordsi

Biological processPhosphate transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:PITA-MONOMER
MetaCyc:PITA-MONOMER

Protein family/group databases

TCDBi2.A.20.1.1 the inorganic phosphate transporter (pit) family

Names & Taxonomyi

Protein namesi
Recommended name:
Low-affinity inorganic phosphate transporter 1
Gene namesi
Name:pitA
Synonyms:pit
Ordered Locus Names:b3493, JW3460
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12230 pitA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 4PeriplasmicSequence analysis4
Transmembranei5 – 25HelicalSequence analysisAdd BLAST21
Topological domaini26 – 51CytoplasmicSequence analysisAdd BLAST26
Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Topological domaini73 – 93PeriplasmicSequence analysisAdd BLAST21
Transmembranei94 – 114HelicalSequence analysisAdd BLAST21
Topological domaini115 – 123CytoplasmicSequence analysis9
Transmembranei124 – 144HelicalSequence analysisAdd BLAST21
Topological domaini145 – 154PeriplasmicSequence analysis10
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Topological domaini176 – 206CytoplasmicSequence analysisAdd BLAST31
Transmembranei207 – 227HelicalSequence analysisAdd BLAST21
Topological domaini228 – 232PeriplasmicSequence analysis5
Transmembranei233 – 253HelicalSequence analysisAdd BLAST21
Topological domaini254 – 381CytoplasmicSequence analysisAdd BLAST128
Transmembranei382 – 402HelicalSequence analysisAdd BLAST21
Topological domaini403 – 429PeriplasmicSequence analysisAdd BLAST27
Transmembranei430 – 450HelicalSequence analysisAdd BLAST21
Topological domaini451 – 472CytoplasmicSequence analysisAdd BLAST22
Transmembranei473 – 493HelicalSequence analysisAdd BLAST21
Topological domaini494 – 499PeriplasmicSequence analysis6

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000807821 – 499Low-affinity inorganic phosphate transporter 1Add BLAST499

Proteomic databases

PaxDbiP0AFJ7
PRIDEiP0AFJ7

Interactioni

Protein-protein interaction databases

BioGridi4262094, 5 interactors
STRINGi316385.ECDH10B_3669

Structurei

3D structure databases

ProteinModelPortaliP0AFJ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CJ3 Bacteria
COG0306 LUCA
HOGENOMiHOG000231893
InParanoidiP0AFJ7
KOiK16322
OMAiGYDITRT
PhylomeDBiP0AFJ7

Family and domain databases

InterProiView protein in InterPro
IPR001204 Phos_transporter
PANTHERiPTHR11101 PTHR11101, 1 hit
PfamiView protein in Pfam
PF01384 PHO4, 1 hit

Sequencei

Sequence statusi: Complete.

P0AFJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHLFAGLDL HTGLLLLLAL AFVLFYEAIN GFHDTANAVA TVIYTRAMRS
60 70 80 90 100
QLAVVMAAVF NFLGVLLGGL SVAYAIVHML PTDLLLNMGS SHGLAMVFSM
110 120 130 140 150
LLAAIIWNLG TWYFGLPASS SHTLIGAIIG IGLTNALMTG TSVVDALNIP
160 170 180 190 200
KVLSIFGSLI VSPIVGLVFA GGLIFLLRRY WSGTKKRARI HLTPAEREKK
210 220 230 240 250
DGKKKPPFWT RIALILSAIG VAFSHGANDG QKGIGLVMLV LIGVAPAGFV
260 270 280 290 300
VNMNATGYEI TRTRDAINNV EAYFEQHPAL LKQATGADQL VPAPEAGATQ
310 320 330 340 350
PAEFHCHPSN TINALNRLKG MLTTDVESYD KLSLDQRSQM RRIMLCVSDT
360 370 380 390 400
IDKVVKMPGV SADDQRLLKK LKSDMLSTIE YAPVWIIMAV ALALGIGTMI
410 420 430 440 450
GWRRVATTIG EKIGKKGMTY AQGMSAQMTA AVSIGLASYT GMPVSTTHVL
460 470 480 490
SSSVAGTMVV DGGGLQRKTV TSILMAWVFT LPAAVLLSGG LYWLSLQFL
Length:499
Mass (Da):53,389
Last modified:December 20, 2005 - v1
Checksum:i93D551131C524084
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA Translation: AAB18469.1
U00096 Genomic DNA Translation: AAC76518.1
AP009048 Genomic DNA Translation: BAE77801.1
PIRiS47713
RefSeqiNP_417950.1, NC_000913.3
WP_000902780.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76518; AAC76518; b3493
BAE77801; BAE77801; BAE77801
GeneIDi948009
KEGGiecj:JW3460
eco:b3493
PATRICifig|1411691.4.peg.3229

Similar proteinsi

Entry informationi

Entry nameiPITA_ECOLI
AccessioniPrimary (citable) accession number: P0AFJ7
Secondary accession number(s): P37308, Q2M7F5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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