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Protein

Putative permease PerM

Gene

perM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:G7310-MONOMER

Protein family/group databases

TCDBi2.A.86.1.1 the autoinducer-2 exporter (ai-2e) family (formerly the perm family, tc #9,b,22)

Names & Taxonomyi

Protein namesi
Recommended name:
Putative permease PerM
Gene namesi
Name:perM
Synonyms:yfgO
Ordered Locus Names:b2493, JW2478
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14221 perM

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 39HelicalSequence analysisAdd BLAST21
Transmembranei72 – 92HelicalSequence analysisAdd BLAST21
Transmembranei156 – 176HelicalSequence analysisAdd BLAST21
Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
Transmembranei240 – 260HelicalSequence analysisAdd BLAST21
Transmembranei281 – 301HelicalSequence analysisAdd BLAST21
Transmembranei310 – 330HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001482941 – 353Putative permease PerMAdd BLAST353

Proteomic databases

PaxDbiP0AFI9
PRIDEiP0AFI9

Interactioni

Protein-protein interaction databases

BioGridi4261433, 30 interactors
IntActiP0AFI9, 1 interactor
STRINGi316385.ECDH10B_2659

Structurei

3D structure databases

ProteinModelPortaliP0AFI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C02 Bacteria
COG0628 LUCA
HOGENOMiHOG000275836
InParanoidiP0AFI9
KOiK03548
OMAiFSIFACG
PhylomeDBiP0AFI9

Family and domain databases

InterProiView protein in InterPro
IPR002549 AI-2E-like
PANTHERiPTHR21716 PTHR21716, 1 hit
PfamiView protein in Pfam
PF01594 AI-2E_transport, 1 hit

Sequencei

Sequence statusi: Complete.

P0AFI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEMLMQWYR RRFSDPEAIA LLVILVAGFG IIFFFSGLLA PLLVAIVLAY
60 70 80 90 100
LLEWPTVRLQ SIGCSRRWAT SIVLVVFVGI LLLMAFVVLP IAWQQGIYLI
110 120 130 140 150
RDMPGMLNKL SDFAATLPRR YPALMDAGII DAMAENMRSR MLTMGDSVVK
160 170 180 190 200
ISLASLVGLL TIAVYLVLVP LMVFFLLKDK EQMLNAVRRV LPRNRGLAGQ
210 220 230 240 250
VWKEMNQQIT NYIRGKVLEM IVVGIATWLG FLLFGLNYSL LLAVLVGFSV
260 270 280 290 300
LIPYIGAFVV TIPVVGVALF QFGAGTEFWS CFAVYLIIQA LDGNLLVPVL
310 320 330 340 350
FSEAVNLHPL VIILSVVIFG GLWGFWGVFF AIPLATLIKA VIHAWPDGQI

AQE
Length:353
Mass (Da):39,194
Last modified:December 20, 2005 - v1
Checksum:iE1CB8EB1E242FC3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75546.1
AP009048 Genomic DNA Translation: BAA16382.1
M63654 Genomic DNA Translation: AAB88575.1
PIRiD65025
RefSeqiNP_416988.1, NC_000913.3
WP_000892044.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75546; AAC75546; b2493
BAA16382; BAA16382; BAA16382
GeneIDi945894
KEGGiecj:JW2478
eco:b2493
PATRICifig|1411691.4.peg.4246

Similar proteinsi

Entry informationi

Entry nameiPERM_ECOLI
AccessioniPrimary (citable) accession number: P0AFI9
Secondary accession number(s): P71230, P77406
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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