Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Oligopeptide transport system permease protein OppC

Gene

oppC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Peptide transport, Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:OPPC-MONOMER.
ECOL316407:JW1237-MONOMER.
MetaCyc:OPPC-MONOMER.

Protein family/group databases

TCDBi3.A.1.5.41. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Oligopeptide transport system permease protein OppC
Gene namesi
Name:oppC
Ordered Locus Names:b1245, JW1237
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10676. oppC.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3737Cytoplasmic1 PublicationAdd
BLAST
Transmembranei38 – 5922HelicalCuratedAdd
BLAST
Topological domaini60 – 10243Extracellular1 PublicationAdd
BLAST
Transmembranei103 – 12220HelicalCuratedAdd
BLAST
Topological domaini123 – 13917Cytoplasmic1 PublicationAdd
BLAST
Transmembranei140 – 16021HelicalCuratedAdd
BLAST
Topological domaini161 – 1633Extracellular1 Publication
Transmembranei164 – 18017HelicalCuratedAdd
BLAST
Topological domaini181 – 21535Cytoplasmic1 PublicationAdd
BLAST
Transmembranei216 – 23621HelicalCuratedAdd
BLAST
Topological domaini237 – 26731Extracellular1 PublicationAdd
BLAST
Transmembranei268 – 29023HelicalCuratedAdd
BLAST
Topological domaini291 – 30212Cytoplasmic1 PublicationAdd
BLAST

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302Oligopeptide transport system permease protein OppCPRO_0000060149Add
BLAST

Proteomic databases

EPDiP0AFH6.
PaxDbiP0AFH6.

Interactioni

Protein-protein interaction databases

BioGridi4261369. 379 interactions.
STRINGi511145.b1245.

Structurei

3D structure databases

ProteinModelPortaliP0AFH6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini101 – 290190ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C2T. Bacteria.
COG1173. LUCA.
HOGENOMiHOG000171367.
InParanoidiP0AFH6.
KOiK15582.
OMAiIVVRHIV.
PhylomeDBiP0AFH6.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
IPR025966. OppC_N.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
PF12911. OppC_N. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMLSKKNSET LENFSEKLEV EGRSLWQDAR RRFMHNRAAV ASLIVLVLIA
60 70 80 90 100
LFVILAPMLS QFAYDDTDWA MMSSAPDMES GHYFGTDSSG RDLLVRVAIG
110 120 130 140 150
GRISLMVGVA AALVAVVVGT LYGSLSGYLG GKVDSVMMRL LEILNSFPFM
160 170 180 190 200
FFVILLVTFF GQNILLIFVA IGMVSWLDMA RIVRGQTLSL KRKEFIEAAQ
210 220 230 240 250
VGGVSTSGIV IRHIVPNVLG VVVVYASLLV PSMILFESFL SFLGLGTQEP
260 270 280 290 300
LSSWGALLSD GANSMEVSPW LLLFPAGFLV VTLFCFNFIG DGLRDALDPK

DR
Length:302
Mass (Da):33,022
Last modified:December 20, 2005 - v1
Checksum:i875829FDFFF513D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74327.1.
AP009048 Genomic DNA. Translation: BAA14777.1.
PIRiH64871.
RefSeqiNP_415761.1. NC_000913.3.
WP_000979661.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74327; AAC74327; b1245.
BAA14777; BAA14777; BAA14777.
GeneIDi945810.
KEGGiecj:JW1237.
eco:b1245.
PATRICi32117750. VBIEscCol129921_1295.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74327.1.
AP009048 Genomic DNA. Translation: BAA14777.1.
PIRiH64871.
RefSeqiNP_415761.1. NC_000913.3.
WP_000979661.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFH6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261369. 379 interactions.
STRINGi511145.b1245.

Protein family/group databases

TCDBi3.A.1.5.41. the atp-binding cassette (abc) superfamily.

Proteomic databases

EPDiP0AFH6.
PaxDbiP0AFH6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74327; AAC74327; b1245.
BAA14777; BAA14777; BAA14777.
GeneIDi945810.
KEGGiecj:JW1237.
eco:b1245.
PATRICi32117750. VBIEscCol129921_1295.

Organism-specific databases

EchoBASEiEB0670.
EcoGeneiEG10676. oppC.

Phylogenomic databases

eggNOGiENOG4105C2T. Bacteria.
COG1173. LUCA.
HOGENOMiHOG000171367.
InParanoidiP0AFH6.
KOiK15582.
OMAiIVVRHIV.
PhylomeDBiP0AFH6.

Enzyme and pathway databases

BioCyciEcoCyc:OPPC-MONOMER.
ECOL316407:JW1237-MONOMER.
MetaCyc:OPPC-MONOMER.

Miscellaneous databases

PROiP0AFH6.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
IPR025966. OppC_N.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
PF12911. OppC_N. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOPPC_ECOLI
AccessioniPrimary (citable) accession number: P0AFH6
Secondary accession number(s): P77664
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.