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Protein

Oligopeptide transport system permease protein OppB

Gene

oppB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

  • oligopeptide-transporting ATPase activity Source: EcoCyc
  • tripeptide transporter activity Source: EcoCyc

GO - Biological processi

  • protein transport Source: UniProtKB-KW
  • tripeptide transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Peptide transport, Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:OPPB-MONOMER.
ECOL316407:JW1236-MONOMER.
MetaCyc:OPPB-MONOMER.

Protein family/group databases

TCDBi3.A.1.5.41. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Oligopeptide transport system permease protein OppB
Gene namesi
Name:oppB
Ordered Locus Names:b1244, JW1236
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10675. oppB.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 9Cytoplasmic1 Publication9
Transmembranei10 – 30HelicalCuratedAdd BLAST21
Topological domaini31 – 99Extracellular1 PublicationAdd BLAST69
Transmembranei100 – 121HelicalCuratedAdd BLAST22
Topological domaini122 – 137Cytoplasmic1 PublicationAdd BLAST16
Transmembranei138 – 158HelicalCuratedAdd BLAST21
Topological domaini159 – 172Extracellular1 PublicationAdd BLAST14
Transmembranei173 – 190HelicalCuratedAdd BLAST18
Topological domaini191 – 226Cytoplasmic1 PublicationAdd BLAST36
Transmembranei227 – 250HelicalCuratedAdd BLAST24
Topological domaini251 – 271Extracellular1 PublicationAdd BLAST21
Transmembranei272 – 293HelicalCuratedAdd BLAST22
Topological domaini294 – 306Cytoplasmic1 PublicationAdd BLAST13

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000601431 – 306Oligopeptide transport system permease protein OppBAdd BLAST306

Proteomic databases

EPDiP0AFH2.
PaxDbiP0AFH2.
PRIDEiP0AFH2.

Interactioni

Protein-protein interaction databases

BioGridi4261152. 226 interactors.
DIPiDIP-48074N.
STRINGi511145.b1244.

Structurei

3D structure databases

ProteinModelPortaliP0AFH2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini94 – 293ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST200

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CJM. Bacteria.
COG0601. LUCA.
HOGENOMiHOG000170249.
InParanoidiP0AFH2.
KOiK15581.
OMAiANSFIFI.
PhylomeDBiP0AFH2.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AFH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKFILRRCL EAIPTLFILI TISFFMMRLA PGSPFTGERT LPPEVMANIE
60 70 80 90 100
AKYHLNDPIM TQYFSYLKQL AHGDFGPSFK YKDYSVNDLV ASSFPVSAKL
110 120 130 140 150
GAAAFFLAVI LGVSAGVIAA LKQNTKWDYT VMGLAMTGVV IPSFVVAPLL
160 170 180 190 200
VMIFAIILHW LPGGGWNGGA LKFMILPMVA LSLAYIASIA RITRGSMIEV
210 220 230 240 250
LHSNFIRTAR AKGLPMRRII LRHALKPALL PVLSYMGPAF VGIITGSMVI
260 270 280 290 300
ETIYGLPGIG QLFVNGALNR DYSLVLSLTI LVGALTILFN AIVDVLYAVI

DPKIRY
Length:306
Mass (Da):33,443
Last modified:December 20, 2005 - v1
Checksum:iF74579B3F9EA4615
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74326.1.
AP009048 Genomic DNA. Translation: BAA14776.1.
J05433 Genomic DNA. No translation available.
PIRiG64871. B36263.
RefSeqiNP_415760.1. NC_000913.3.
WP_000911112.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74326; AAC74326; b1244.
BAA14776; BAA14776; BAA14776.
GeneIDi945823.
KEGGiecj:JW1236.
eco:b1244.
PATRICi32117748. VBIEscCol129921_1294.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74326.1.
AP009048 Genomic DNA. Translation: BAA14776.1.
J05433 Genomic DNA. No translation available.
PIRiG64871. B36263.
RefSeqiNP_415760.1. NC_000913.3.
WP_000911112.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AFH2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261152. 226 interactors.
DIPiDIP-48074N.
STRINGi511145.b1244.

Protein family/group databases

TCDBi3.A.1.5.41. the atp-binding cassette (abc) superfamily.

Proteomic databases

EPDiP0AFH2.
PaxDbiP0AFH2.
PRIDEiP0AFH2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74326; AAC74326; b1244.
BAA14776; BAA14776; BAA14776.
GeneIDi945823.
KEGGiecj:JW1236.
eco:b1244.
PATRICi32117748. VBIEscCol129921_1294.

Organism-specific databases

EchoBASEiEB0669.
EcoGeneiEG10675. oppB.

Phylogenomic databases

eggNOGiENOG4105CJM. Bacteria.
COG0601. LUCA.
HOGENOMiHOG000170249.
InParanoidiP0AFH2.
KOiK15581.
OMAiANSFIFI.
PhylomeDBiP0AFH2.

Enzyme and pathway databases

BioCyciEcoCyc:OPPB-MONOMER.
ECOL316407:JW1236-MONOMER.
MetaCyc:OPPB-MONOMER.

Miscellaneous databases

PROiP0AFH2.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOPPB_ECOLI
AccessioniPrimary (citable) accession number: P0AFH2
Secondary accession number(s): P31132, P76026, P77550
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: November 2, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.