P0AF40 (YIJD_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Inner membrane protein YijD

Gene names

Name:	yijD
Ordered Locus Names:	b3964, JW3936

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	119 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 119	119	Inner membrane protein YijD		PRO_0000169698
Regions
	Topological domain	1 – 8	8	Cytoplasmic Potential
	Transmembrane	9 – 28	20	Helical; Potential
	Topological domain	29 – 31	3	Periplasmic Potential
	Transmembrane	32 – 50	19	Helical; Potential
	Topological domain	51 – 61	11	Cytoplasmic Potential
	Transmembrane	62 – 84	23	Helical; Potential
	Topological domain	85 – 88	4	Periplasmic Potential
	Transmembrane	89 – 108	20	Helical; Potential
	Topological domain	109 – 119	11	Cytoplasmic Potential
Experimental info
	Sequence conflict	13	1	L → LL in CAA46824. Ref.1
	Sequence conflict	94	1	F → L in CAA46824. Ref.1
	Sequence conflict	100 – 110	11	VIMVFWIGAKM → SLWCSGLARRW in CAA46824. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P0AF40 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: 29177570EAF20F3B	FASTA	119	13,024
	10 20 30 40 50 60 MKQANQDRGT LLLALVAGLS INGTFAALFS SIVPFSVFPI ISLVLTVYCL HQRYLNRTMP 70 80 90 100 110 VGLPGLAAAC FILGVLLYST VVRAEYPDIG SNFFPAVLSV IMVFWIGAKM RNRKQEVAE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Physical map of the oxyR-trmA region (minute 89.3) of the Escherichia coli chromosome." Gustafsson C., Warne S.R. J. Bacteriol. 174:7878-7879(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[2]	"Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes." Blattner F.R., Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L. Nucleic Acids Res. 21:5408-5417(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]	"Global topology analysis of the Escherichia coli inner membrane proteome." Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G. Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: K12 / MG1655 / ATCC 47076.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X66026 Genomic DNA. Translation: CAA46824.1. U00006 Genomic DNA. Translation: AAC43070.1. U00096 Genomic DNA. Translation: AAC76946.1. AP009048 Genomic DNA. Translation: BAE77347.1.
PIR	G65203. S21565.
RefSeq	NP_418399.1. NC_000913.2. YP_491488.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P0AF40.
ModBase	Search...
Protein-protein interaction databases
STRING	511145.b3964.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC76946; AAC76946; b3964. BAE77347; BAE77347; BAE77347.
GeneID	12933189. 948459.
KEGG	ecj:Y75_p3224. eco:b3964.
PATRIC	32123449. VBIEscCol129921_4085.
Organism-specific databases
EchoBASE	EB1368.
EcoGene	EG11395. yijD.
Phylogenomic databases
eggNOG	NOG06042.
HOGENOM	HOG000270375.
OMA	EAGSNFF.
ProtClustDB	PRK11056.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11395-MONOMER. ECOL316407:JW3936-MONOMER.
Gene expression databases
Genevestigator	P0AF40.
Family and domain databases
InterPro	IPR009867. DUF1422. [Graphical view]
Pfam	PF07226. DUF1422. 1 hit. [Graphical view]
ProDom	PD076479. DUF1422. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

YIJD_ECOLI

Accession

Primary (citable) accession number: P0AF40
Secondary accession number(s): P27308, Q2M8Q9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program