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P0AEY0 (MALE_ECO57) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Maltose-binding periplasmic protein
Alternative name(s):
MBP
MMBP
Maltodextrin-binding protein
Gene names
Name:malE
Ordered Locus Names:Z5632, ECs5017
OrganismEscherichia coli O157:H7 [Complete proteome] [HAMAP]
Taxonomic identifier83334 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides By similarity.

Subcellular location

Periplasm By similarity.

Sequence similarities

Belongs to the bacterial solute-binding protein 1 family.

Ontologies

Keywords
   Biological processSugar transport
Transport
   Cellular componentPeriplasm
   DomainSignal
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmaltose transmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2626 By similarity
Chain27 – 396370Maltose-binding periplasmic protein
PRO_0000044622

Secondary structure

................................................................... 396
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P0AEY0 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: A4C1B3C1777ADE47

FASTA39643,388
        10         20         30         40         50         60 
MKIKTGARIL ALSALTTMMF SASALAKIEE GKLVIWINGD KGYNGLAEVG KKFEKDTGIK 

        70         80         90        100        110        120 
VTVEHPDKLE EKFPQVAATG DGPDIIFWAH DRFGGYAQSG LLAEITPDKA FQDKLYPFTW 

       130        140        150        160        170        180 
DAVRYNGKLI AYPIAVEALS LIYNKDLLPN PPKTWEEIPA LDKELKAKGK SALMFNLQEP 

       190        200        210        220        230        240 
YFTWPLIAAD GGYAFKYENG KYDIKDVGVD NAGAKAGLTF LVDLIKNKHM NADTDYSIAE 

       250        260        270        280        290        300 
AAFNKGETAM TINGPWAWSN IDTSKVNYGV TVLPTFKGQP SKPFVGVLSA GINAASPNKE 

       310        320        330        340        350        360 
LAKEFLENYL LTDEGLEAVN KDKPLGAVAL KSYEEELAKD PRIAATMENA QKGEIMPNIP 

       370        380        390 
QMSAFWYAVR TAVINAASGR QTVDEALKDA QTRITK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005174 Genomic DNA. Translation: AAG59233.1.
BA000007 Genomic DNA. Translation: BAB38440.1.
PIRA98256.
E86096.
RefSeqNP_290668.1. NC_002655.2.
NP_313044.1. NC_002695.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3VD8X-ray2.07A27-392[»]
4MY2X-ray2.40A26-392[»]
ProteinModelPortalP0AEY0.
SMRP0AEY0. Positions 27-392.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP0AEY0. 1 interaction.
MINTMINT-6765486.
STRING155864.Z5632.

Proteomic databases

PRIDEP0AEY0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG59233; AAG59233; Z5632.
BAB38440; BAB38440; BAB38440.
GeneID914317.
960089.
KEGGece:Z5632.
ecs:ECs5017.
PATRIC18359629. VBIEscCol44059_4951.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2182.
HOGENOMHOG000055250.
KOK10108.
OMANDSDYAS.
OrthoDBEOG6CCH2B.
ProtClustDBPRK09474.

Enzyme and pathway databases

BioCycECOL386585:GJFA-5020-MONOMER.
ECOO157:MALE-MONOMER.

Family and domain databases

InterProIPR006060. Maltose-bd.
IPR006059. Solute-bd_1_bac.
IPR006061. Solute-bd_1_bac_CS.
[Graphical view]
PfamPF01547. SBP_bac_1. 1 hit.
[Graphical view]
PRINTSPR00181. MALTOSEBP.
PROSITEPS01037. SBP_BACTERIAL_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMALE_ECO57
AccessionPrimary (citable) accession number: P0AEY0
Secondary accession number(s): P02928
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references