Reviewed, UniProtKB/Swiss-Prot P0AEW4 (ICC_ECOLI)

Names and origin

Protein names

Recommended name:
    Protein icc

Gene names

Name:	icc
Ordered Locus Names:	b3032, JW3000

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Predicted.

General annotation (Comments)

Function

Affects the expression of the lacZ gene.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 275	275	Protein icc		PRO_0000084146

Sequences

	Sequence		Length	Mass (Da)
	P0AEW4-1 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: 97696478536CFBF1	FASTA	275	30,938
	10 20 30 40 50 60 MESLLTLPLA GEARVRILQI TDTHLFAQKH EALLGVNTWE SYQAVLEAIR PHQHEFDLIV 70 80 90 100 110 120 ATGDLAQDQS SAAYQHFAEG IASFRAPCVW LPGNHDFQPA MYSALQDAGI SPAKRVFIGE 130 140 150 160 170 180 QWQILLLDSQ VFGVPHGELS EFQLEWLERK LADAPERHTL LLLHHHPLPA GCSWLDQHSL 190 200 210 220 230 240 RNAGELDTVL AKFPHVKYLL CGHIHQELDL DWNGRRLLAT PSTCVQFKPH CSNFTLDTIA 250 260 270 PGWRTLELHA DGTLTTEVHR LADTRFQPDT ASEGY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of the cpdA gene encoding cyclic 3',5'-adenosine monophosphate phosphodiesterase in Escherichia coli." Imamura R., Yamanaka K., Ogura T., Hiraga S., Fujita N., Ishihama A., Niki H. J. Biol. Chem. 271:25423-25429(1996) [PubMed: 8810311] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D16557 Genomic DNA. Translation: BAA03989.1. U28377 Genomic DNA. Translation: AAA69200.1. Different initiation. U00096 Genomic DNA. Translation: AAC76068.1. AP009048 Genomic DNA. Translation: BAE77088.1.
PIR	F65090.
RefSeq	AP_003582.1. NP_417504.1.
3D structure databases
SMR	P0AEW4. Positions 15-261.
ModBase	Search...
Protein-protein interaction databases
STRING	P0AEW4.
Genome annotation databases
GeneID	947515.
GenomeReviews	Gene locus JW3000 in contig AP009048_GR. Gene locus b3032 in contig U00096_GR.
KEGG	ecj:JW3000. eco:b3032.
Organism-specific databases
EchoBASE	EB2104.
EcoGene	EG12187. icc.
CMR	Search...
Phylogenomic databases
eggNOG	COG1409.
HOGENOM	HBG285602.
OMA	LLQITDT.
Enzyme and pathway databases
BioCyc	EcoCyc:G7579-MONOMER. ECOL168927:B3032-MONOMER. MetaCyc:G7579-MONOMER.
Gene expression databases
Genevestigator	P0AEW4.
Family and domain databases
InterPro	IPR013622. Calcineurin-like_phos_C. IPR004843. M-pesterase. [Graphical view]
Pfam	PF00149. Metallophos. 1 hit. PF08413. Metallophos_C. 1 hit. [Graphical view]
ProDom	PD587589. Calcineurin-like_phos_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ICC_ECOLI

Accession

Primary (citable) accession number: P0AEW4
Secondary accession number(s): P36650, Q2M9G8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	January 19, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)