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Protein

Protein HdeD

Gene

hdeD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • response to pH Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11495-MONOMER.
ECOL316407:JW3479-MONOMER.

Protein family/group databases

TCDBi9.B.36.1.1. the acid resistance membrane protein (hded) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HdeD
Gene namesi
Name:hdeD
Synonyms:yhiA
Ordered Locus Names:b3511, JW3479
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11495. hdeD.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2525CytoplasmicSequence analysisAdd
BLAST
Transmembranei26 – 4419HelicalSequence analysisAdd
BLAST
Topological domaini45 – 473PeriplasmicSequence analysis
Transmembranei48 – 7023HelicalSequence analysisAdd
BLAST
Topological domaini71 – 766CytoplasmicSequence analysis
Transmembranei77 – 9923HelicalSequence analysisAdd
BLAST
Topological domaini100 – 1034PeriplasmicSequence analysis
Transmembranei104 – 12623HelicalSequence analysisAdd
BLAST
Topological domaini127 – 13812CytoplasmicSequence analysisAdd
BLAST
Transmembranei139 – 16123HelicalSequence analysisAdd
BLAST
Topological domaini162 – 1643PeriplasmicSequence analysis
Transmembranei165 – 18723HelicalSequence analysisAdd
BLAST
Topological domaini188 – 1903CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 190190Protein HdeDPRO_0000083935Add
BLAST

Proteomic databases

PaxDbiP0AET5.
PRIDEiP0AET5.

Interactioni

Protein-protein interaction databases

BioGridi4259561. 5 interactions.
DIPiDIP-48170N.
IntActiP0AET5. 1 interaction.
MINTiMINT-1261306.
STRINGi511145.b3511.

Structurei

3D structure databases

ProteinModelPortaliP0AET5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108YK4. Bacteria.
COG3247. LUCA.
HOGENOMiHOG000125837.
InParanoidiP0AET5.
OMAiIGVEMIF.
OrthoDBiEOG65N195.

Family and domain databases

InterProiIPR005325. DUF308_memb.
[Graphical view]
PfamiPF03729. DUF308. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AET5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYIDKATIL KFDLEMLKKH RRAIQFIAVL LFIVGLLCIS FPFVSGDILS
60 70 80 90 100
TVVGALLICS GIALIVGLFS NRSHNFWPVL SGFLVAVAYL LIGYFFIRAP
110 120 130 140 150
ELGIFAIAAF IAGLFCVAGV IRLMSWYRQR SMKGSWLQLV IGVLDIVIAW
160 170 180 190
IFLGATPMVS VTLVSTLVGI ELIFSAASLF SFASLFVKQQ
Length:190
Mass (Da):20,903
Last modified:December 20, 2005 - v1
Checksum:i59FEAD58A13F7ECE
GO

Sequence cautioni

The sequence BAA01882.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11389 Genomic DNA. Translation: BAA01985.1.
U00039 Genomic DNA. Translation: AAB18487.1.
U00096 Genomic DNA. Translation: AAC76536.1.
AP009048 Genomic DNA. Translation: BAE77783.1.
D11109 Genomic DNA. Translation: BAA01882.1. Different initiation.
PIRiS47731.
RefSeqiNP_417968.1. NC_000913.3.
WP_000965672.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76536; AAC76536; b3511.
BAE77783; BAE77783; BAE77783.
GeneIDi948024.
KEGGiecj:JW3479.
eco:b3511.
PATRICi32122480. VBIEscCol129921_3618.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11389 Genomic DNA. Translation: BAA01985.1.
U00039 Genomic DNA. Translation: AAB18487.1.
U00096 Genomic DNA. Translation: AAC76536.1.
AP009048 Genomic DNA. Translation: BAE77783.1.
D11109 Genomic DNA. Translation: BAA01882.1. Different initiation.
PIRiS47731.
RefSeqiNP_417968.1. NC_000913.3.
WP_000965672.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AET5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259561. 5 interactions.
DIPiDIP-48170N.
IntActiP0AET5. 1 interaction.
MINTiMINT-1261306.
STRINGi511145.b3511.

Protein family/group databases

TCDBi9.B.36.1.1. the acid resistance membrane protein (hded) family.

Proteomic databases

PaxDbiP0AET5.
PRIDEiP0AET5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76536; AAC76536; b3511.
BAE77783; BAE77783; BAE77783.
GeneIDi948024.
KEGGiecj:JW3479.
eco:b3511.
PATRICi32122480. VBIEscCol129921_3618.

Organism-specific databases

EchoBASEiEB1458.
EcoGeneiEG11495. hdeD.

Phylogenomic databases

eggNOGiENOG4108YK4. Bacteria.
COG3247. LUCA.
HOGENOMiHOG000125837.
InParanoidiP0AET5.
OMAiIGVEMIF.
OrthoDBiEOG65N195.

Enzyme and pathway databases

BioCyciEcoCyc:EG11495-MONOMER.
ECOL316407:JW3479-MONOMER.

Miscellaneous databases

PROiP0AET5.

Family and domain databases

InterProiIPR005325. DUF308_memb.
[Graphical view]
PfamiPF03729. DUF308. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Physical map location of a set of Escherichia coli genes (hde) whose expression is affected by the nucleoid protein H-NS."
    Yoshida T., Ueguchi C., Mizuno T.
    J. Bacteriol. 175:7747-7748(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes."
    Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.
    Nucleic Acids Res. 22:2576-2586(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Function of the Escherichia coli nucleoid protein, H-NS: molecular analysis of a subset of proteins whose expression is enhanced in a hns deletion mutant."
    Yoshida T., Ueguchi C., Yamada H., Mizuno T.
    Mol. Gen. Genet. 237:113-122(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-106.
    Strain: K12.
  6. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiHDED_ECOLI
AccessioniPrimary (citable) accession number: P0AET5
Secondary accession number(s): P26603, P28326, Q2M7H3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 20, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.