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Protein

Protein HdeD

Gene

hdeD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • response to pH Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:EG11495-MONOMER

Protein family/group databases

TCDBi9.B.36.1.1 the acid resistance membrane protein (hded) family

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HdeD
Gene namesi
Name:hdeD
Synonyms:yhiA
Ordered Locus Names:b3511, JW3479
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11495 hdeD

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25CytoplasmicSequence analysisAdd BLAST25
Transmembranei26 – 44HelicalSequence analysisAdd BLAST19
Topological domaini45 – 47PeriplasmicSequence analysis3
Transmembranei48 – 70HelicalSequence analysisAdd BLAST23
Topological domaini71 – 76CytoplasmicSequence analysis6
Transmembranei77 – 99HelicalSequence analysisAdd BLAST23
Topological domaini100 – 103PeriplasmicSequence analysis4
Transmembranei104 – 126HelicalSequence analysisAdd BLAST23
Topological domaini127 – 138CytoplasmicSequence analysisAdd BLAST12
Transmembranei139 – 161HelicalSequence analysisAdd BLAST23
Topological domaini162 – 164PeriplasmicSequence analysis3
Transmembranei165 – 187HelicalSequence analysisAdd BLAST23
Topological domaini188 – 190CytoplasmicSequence analysis3

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000839351 – 190Protein HdeDAdd BLAST190

Proteomic databases

PaxDbiP0AET5
PRIDEiP0AET5

Interactioni

Protein-protein interaction databases

BioGridi4259561, 5 interactors
DIPiDIP-48170N
IntActiP0AET5, 1 interactor
STRINGi316385.ECDH10B_3687

Structurei

3D structure databases

ProteinModelPortaliP0AET5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108YK4 Bacteria
COG3247 LUCA
HOGENOMiHOG000125837
InParanoidiP0AET5
KOiK21908
OMAiVNSLWVL

Family and domain databases

InterProiView protein in InterPro
IPR005325 DUF308_memb
PfamiView protein in Pfam
PF03729 DUF308, 2 hits

Sequencei

Sequence statusi: Complete.

P0AET5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYIDKATIL KFDLEMLKKH RRAIQFIAVL LFIVGLLCIS FPFVSGDILS
60 70 80 90 100
TVVGALLICS GIALIVGLFS NRSHNFWPVL SGFLVAVAYL LIGYFFIRAP
110 120 130 140 150
ELGIFAIAAF IAGLFCVAGV IRLMSWYRQR SMKGSWLQLV IGVLDIVIAW
160 170 180 190
IFLGATPMVS VTLVSTLVGI ELIFSAASLF SFASLFVKQQ
Length:190
Mass (Da):20,903
Last modified:December 20, 2005 - v1
Checksum:i59FEAD58A13F7ECE
GO

Sequence cautioni

The sequence BAA01882 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11389 Genomic DNA Translation: BAA01985.1
U00039 Genomic DNA Translation: AAB18487.1
U00096 Genomic DNA Translation: AAC76536.1
AP009048 Genomic DNA Translation: BAE77783.1
D11109 Genomic DNA Translation: BAA01882.1 Different initiation.
PIRiS47731
RefSeqiNP_417968.1, NC_000913.3
WP_000965672.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76536; AAC76536; b3511
BAE77783; BAE77783; BAE77783
GeneIDi948024
KEGGiecj:JW3479
eco:b3511
PATRICifig|1411691.4.peg.3208

Similar proteinsi

Entry informationi

Entry nameiHDED_ECOLI
AccessioniPrimary (citable) accession number: P0AET5
Secondary accession number(s): P26603, P28326, Q2M7H3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health