Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein HdeD

Gene

hdeD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • response to pH Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11495-MONOMER.
ECOL316407:JW3479-MONOMER.

Protein family/group databases

TCDBi9.B.36.1.1. the acid resistance membrane protein (hded) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HdeD
Gene namesi
Name:hdeD
Synonyms:yhiA
Ordered Locus Names:b3511, JW3479
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11495. hdeD.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25CytoplasmicSequence analysisAdd BLAST25
Transmembranei26 – 44HelicalSequence analysisAdd BLAST19
Topological domaini45 – 47PeriplasmicSequence analysis3
Transmembranei48 – 70HelicalSequence analysisAdd BLAST23
Topological domaini71 – 76CytoplasmicSequence analysis6
Transmembranei77 – 99HelicalSequence analysisAdd BLAST23
Topological domaini100 – 103PeriplasmicSequence analysis4
Transmembranei104 – 126HelicalSequence analysisAdd BLAST23
Topological domaini127 – 138CytoplasmicSequence analysisAdd BLAST12
Transmembranei139 – 161HelicalSequence analysisAdd BLAST23
Topological domaini162 – 164PeriplasmicSequence analysis3
Transmembranei165 – 187HelicalSequence analysisAdd BLAST23
Topological domaini188 – 190CytoplasmicSequence analysis3

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000839351 – 190Protein HdeDAdd BLAST190

Proteomic databases

PaxDbiP0AET5.
PRIDEiP0AET5.

Interactioni

Protein-protein interaction databases

BioGridi4259561. 5 interactors.
DIPiDIP-48170N.
IntActiP0AET5. 1 interactor.
MINTiMINT-1261306.
STRINGi511145.b3511.

Structurei

3D structure databases

ProteinModelPortaliP0AET5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108YK4. Bacteria.
COG3247. LUCA.
HOGENOMiHOG000125837.
InParanoidiP0AET5.
OMAiIGVEMIF.

Family and domain databases

InterProiIPR005325. DUF308_memb.
[Graphical view]
PfamiPF03729. DUF308. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AET5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYIDKATIL KFDLEMLKKH RRAIQFIAVL LFIVGLLCIS FPFVSGDILS
60 70 80 90 100
TVVGALLICS GIALIVGLFS NRSHNFWPVL SGFLVAVAYL LIGYFFIRAP
110 120 130 140 150
ELGIFAIAAF IAGLFCVAGV IRLMSWYRQR SMKGSWLQLV IGVLDIVIAW
160 170 180 190
IFLGATPMVS VTLVSTLVGI ELIFSAASLF SFASLFVKQQ
Length:190
Mass (Da):20,903
Last modified:December 20, 2005 - v1
Checksum:i59FEAD58A13F7ECE
GO

Sequence cautioni

The sequence BAA01882 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11389 Genomic DNA. Translation: BAA01985.1.
U00039 Genomic DNA. Translation: AAB18487.1.
U00096 Genomic DNA. Translation: AAC76536.1.
AP009048 Genomic DNA. Translation: BAE77783.1.
D11109 Genomic DNA. Translation: BAA01882.1. Different initiation.
PIRiS47731.
RefSeqiNP_417968.1. NC_000913.3.
WP_000965672.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76536; AAC76536; b3511.
BAE77783; BAE77783; BAE77783.
GeneIDi948024.
KEGGiecj:JW3479.
eco:b3511.
PATRICi32122480. VBIEscCol129921_3618.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11389 Genomic DNA. Translation: BAA01985.1.
U00039 Genomic DNA. Translation: AAB18487.1.
U00096 Genomic DNA. Translation: AAC76536.1.
AP009048 Genomic DNA. Translation: BAE77783.1.
D11109 Genomic DNA. Translation: BAA01882.1. Different initiation.
PIRiS47731.
RefSeqiNP_417968.1. NC_000913.3.
WP_000965672.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AET5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259561. 5 interactors.
DIPiDIP-48170N.
IntActiP0AET5. 1 interactor.
MINTiMINT-1261306.
STRINGi511145.b3511.

Protein family/group databases

TCDBi9.B.36.1.1. the acid resistance membrane protein (hded) family.

Proteomic databases

PaxDbiP0AET5.
PRIDEiP0AET5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76536; AAC76536; b3511.
BAE77783; BAE77783; BAE77783.
GeneIDi948024.
KEGGiecj:JW3479.
eco:b3511.
PATRICi32122480. VBIEscCol129921_3618.

Organism-specific databases

EchoBASEiEB1458.
EcoGeneiEG11495. hdeD.

Phylogenomic databases

eggNOGiENOG4108YK4. Bacteria.
COG3247. LUCA.
HOGENOMiHOG000125837.
InParanoidiP0AET5.
OMAiIGVEMIF.

Enzyme and pathway databases

BioCyciEcoCyc:EG11495-MONOMER.
ECOL316407:JW3479-MONOMER.

Miscellaneous databases

PROiP0AET5.

Family and domain databases

InterProiIPR005325. DUF308_memb.
[Graphical view]
PfamiPF03729. DUF308. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHDED_ECOLI
AccessioniPrimary (citable) accession number: P0AET5
Secondary accession number(s): P26603, P28326, Q2M7H3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: November 2, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.