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Protein

Glutamate/aspartate import permease protein GltJ

Gene

gltJ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for the translocation of the substrate across the membrane.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:GLTJ-MONOMER
MetaCyc:GLTJ-MONOMER

Protein family/group databases

TCDBi3.A.1.3.4 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate/aspartate import permease protein GltJCurated
Gene namesi
Name:gltJ
Ordered Locus Names:b0654, JW0649
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12661 gltJ

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalSequence analysisAdd BLAST21
Transmembranei74 – 94HelicalSequence analysisAdd BLAST21
Transmembranei104 – 124HelicalSequence analysisAdd BLAST21
Transmembranei179 – 196HelicalSequence analysisAdd BLAST18
Transmembranei212 – 232HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • ATP-binding cassette (ABC) transporter complex Source: InterPro
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000600351 – 246Glutamate/aspartate import permease protein GltJAdd BLAST246

Proteomic databases

PaxDbiP0AER3
PRIDEiP0AER3

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (GltL), two transmembrane proteins (GltJ and GltK) and a solute-binding protein (GltI).1 Publication

Protein-protein interaction databases

BioGridi4259914, 5 interactors
DIPiDIP-35965N
IntActiP0AER3, 6 interactors
STRINGi316385.ECDH10B_0723

Structurei

3D structure databases

ProteinModelPortaliP0AER3
SMRiP0AER3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 230ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST202

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EAD Bacteria
COG0765 LUCA
HOGENOMiHOG000267552
InParanoidiP0AER3
KOiK10003
OMAiELMQFQY
PhylomeDBiP0AER3

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.10, 1 hit
InterProiView protein in InterPro
IPR010065 AA_ABC_transptr_permease_3TM
IPR030202 GltJ/AatQ
IPR000515 MetI-like
IPR035906 MetI-like_sf
PANTHERiPTHR30085:SF4 PTHR30085:SF4, 1 hit
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
TIGRFAMsiTIGR01726 HEQRo_perm_3TM, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P0AER3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIDWNWGIF LQQAPFGNTT YLGWIWSGFQ VTIALSICAW IIAFLVGSFF
60 70 80 90 100
GILRTVPNRF LSGLGTLYVE LFRNVPLIVQ FFTWYLVIPE LLPEKIGMWF
110 120 130 140 150
KAELDPNIQF FLSSMLCLGL FTAARVCEQV RAAIQSLPRG QKNAALAMGL
160 170 180 190 200
TLPQAYRYVL LPNAYRVIVP PMTSEMMNLV KNSAIASTIG LVDMAAQAGK
210 220 230 240
LLDYSAHAWE SFTAITLAYV LINAFIMLVM TLVERKVRLP GNMGGK
Length:246
Mass (Da):27,503
Last modified:December 20, 2005 - v1
Checksum:iE9E5CAF26BD252B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10981 Genomic DNA Translation: AAA60980.1
U82598 Genomic DNA Translation: AAB40855.1
U00096 Genomic DNA Translation: AAC73755.1
AP009048 Genomic DNA Translation: BAA35306.1
PIRiD64800
RefSeqiNP_415187.1, NC_000913.3
WP_000020941.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73755; AAC73755; b0654
BAA35306; BAA35306; BAA35306
GeneIDi945443
KEGGiecj:JW0649
eco:b0654
PATRICifig|1411691.4.peg.1614

Similar proteinsi

Entry informationi

Entry nameiGLTJ_ECOLI
AccessioniPrimary (citable) accession number: P0AER3
Secondary accession number(s): P41074
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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