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Protein

Glutamine transport system permease protein GlnP

Gene

glnP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:GLNP-MONOMER.
ECOL316407:JW0795-MONOMER.
MetaCyc:GLNP-MONOMER.

Protein family/group databases

TCDBi3.A.1.3.2. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine transport system permease protein GlnP
Gene namesi
Name:glnP
Ordered Locus Names:b0810, JW0795
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10388. glnP.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 22PeriplasmicSequence analysisAdd BLAST22
Transmembranei23 – 43HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini44 – 53CytoplasmicSequence analysis10
Transmembranei54 – 74HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini75 – 88PeriplasmicSequence analysisAdd BLAST14
Transmembranei89 – 109HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini110 – 150CytoplasmicSequence analysisAdd BLAST41
Transmembranei151 – 171HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini172 – 187PeriplasmicSequence analysisAdd BLAST16
Transmembranei188 – 208HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini209 – 219CytoplasmicSequence analysisAdd BLAST11

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000600301 – 219Glutamine transport system permease protein GlnPAdd BLAST219

Proteomic databases

PaxDbiP0AEQ6.
PRIDEiP0AEQ6.

Expressioni

Inductioni

By lack of glutamine.

Interactioni

Protein-protein interaction databases

BioGridi4259971. 2 interactors.
DIPiDIP-47993N.
STRINGi511145.b0810.

Structurei

3D structure databases

ProteinModelPortaliP0AEQ6.
SMRiP0AEQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 209ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST191

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E5Q. Bacteria.
COG0765. LUCA.
HOGENOMiHOG000267552.
InParanoidiP0AEQ6.
KOiK10037.
OMAiTIRHVIM.
PhylomeDBiP0AEQ6.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AEQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQFDWSAIWP AIPLLIEGAK MTLWISVLGL AGGLVIGLLA GFARTFGGWI
60 70 80 90 100
ANHVALVFIE VIRGTPIVVQ VMFIYFALPM AFNDLRIDPF TAAVVTIMIN
110 120 130 140 150
SGAYIAEITR GAVLSIHKGF REAGLALGLS RWETIRYVIL PLALRRMLPP
160 170 180 190 200
LGNQWIISIK DTSLFIVIGV AELTRQGQEI IAGNFRALEI WSAVAVFYLI
210
ITLVLSFILR RLERRMKIL
Length:219
Mass (Da):24,364
Last modified:December 20, 2005 - v1
Checksum:i20A94A31BE02121C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14180 Genomic DNA. Translation: CAA32383.1.
U00096 Genomic DNA. Translation: AAC73897.1.
AP009048 Genomic DNA. Translation: BAA35482.1.
PIRiS03182. QRECGP.
RefSeqiNP_415331.1. NC_000913.3.
WP_001159065.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73897; AAC73897; b0810.
BAA35482; BAA35482; BAA35482.
GeneIDi945621.
KEGGiecj:JW0795.
eco:b0810.
PATRICi32116823. VBIEscCol129921_0837.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14180 Genomic DNA. Translation: CAA32383.1.
U00096 Genomic DNA. Translation: AAC73897.1.
AP009048 Genomic DNA. Translation: BAA35482.1.
PIRiS03182. QRECGP.
RefSeqiNP_415331.1. NC_000913.3.
WP_001159065.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AEQ6.
SMRiP0AEQ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259971. 2 interactors.
DIPiDIP-47993N.
STRINGi511145.b0810.

Protein family/group databases

TCDBi3.A.1.3.2. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP0AEQ6.
PRIDEiP0AEQ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73897; AAC73897; b0810.
BAA35482; BAA35482; BAA35482.
GeneIDi945621.
KEGGiecj:JW0795.
eco:b0810.
PATRICi32116823. VBIEscCol129921_0837.

Organism-specific databases

EchoBASEiEB0383.
EcoGeneiEG10388. glnP.

Phylogenomic databases

eggNOGiENOG4105E5Q. Bacteria.
COG0765. LUCA.
HOGENOMiHOG000267552.
InParanoidiP0AEQ6.
KOiK10037.
OMAiTIRHVIM.
PhylomeDBiP0AEQ6.

Enzyme and pathway databases

BioCyciEcoCyc:GLNP-MONOMER.
ECOL316407:JW0795-MONOMER.
MetaCyc:GLNP-MONOMER.

Miscellaneous databases

PROiP0AEQ6.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNP_ECOLI
AccessioniPrimary (citable) accession number: P0AEQ6
Secondary accession number(s): P10345, P76825
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: November 2, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.