Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P0AEM8 (FLIA_ECO57) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA polymerase sigma factor FliA
Alternative name(s):
RNA polymerase sigma factor for flagellar operon
Sigma F
Sigma-28
Gene names
Name:fliA
Ordered Locus Names:Z3012, ECs2661
OrganismEscherichia coli O157:H7 [Complete proteome] [HAMAP]
Taxonomic identifier83334 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes By similarity. HAMAP-Rule MF_00962

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00962.

Sequence similarities

Belongs to the sigma-70 factor family. FliA subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 239239RNA polymerase sigma factor FliA HAMAP-Rule MF_00962
PRO_0000093982

Regions

DNA binding207 – 22620H-T-H motif By similarity
Region16 – 8873Sigma-70 factor domain-2 By similarity
Region96 – 16671Sigma-70 factor domain-3 By similarity
Region185 – 23349Sigma-70 factor domain-4 By similarity
Motif43 – 464Interaction with polymerase core subunit RpoC HAMAP-Rule MF_00962

Sequences

Sequence LengthMass (Da)Tools
P0AEM8 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: B2930B44E1F24A33

FASTA23927,521
        10         20         30         40         50         60 
MNSLYTAEGV MDKHSLWQRY VPLVRHEALR LQVRLPASVE LDDLLQAGGI GLLNAVERYD 

        70         80         90        100        110        120 
ALQGTAFTTY AVQRIRGAML DELRSRDWVP RSVRRNAREV AQAIGQLEQE LGRNATETEV 

       130        140        150        160        170        180 
AERLGIDIAD YRQMLLDTNN SQLFSYDEWR EEHGDSIELV TDDHQRENPL QQLLDSNLRQ 

       190        200        210        220        230 
RVMEAIETLP EREKLVLTLY YQEELNLKEI GAVLEVGESR VSQLHSQAIK RLRTKLGKL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005174 Genomic DNA. Translation: AAG56937.1.
BA000007 Genomic DNA. Translation: BAB36084.1.
PIRE85809.
E90961.
RefSeqNP_288383.1. NC_002655.2.
NP_310688.1. NC_002695.1.

3D structure databases

ProteinModelPortalP0AEM8.
SMRP0AEM8. Positions 11-236.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING155864.Z3012.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG56937; AAG56937; Z3012.
BAB36084; BAB36084; BAB36084.
GeneID914052.
961920.
KEGGece:Z3012.
ecs:ECs2661.
PATRIC18354706. VBIEscCol44059_2561.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1191.
HOGENOMHOG000270271.
KOK02405.
OMAVHRNQRR.
OrthoDBEOG661H9F.
ProtClustDBPRK06986.

Enzyme and pathway databases

BioCycECOL386585:GJFA-2628-MONOMER.
ECOO157:FLIA-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 2 hits.
HAMAPMF_00962. Sigma70_FliA.
InterProIPR014284. RNA_pol_sigma-70_dom.
IPR000943. RNA_pol_sigma70.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR012845. RNA_pol_sigma_FliA_WhiG.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR028617. Sigma70_FliA.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
[Graphical view]
PRINTSPR00046. SIGMA70FCT.
SUPFAMSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsTIGR02479. FliA_WhiG. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEPS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFLIA_ECO57
AccessionPrimary (citable) accession number: P0AEM8
Secondary accession number(s): P31804
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: February 19, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families