Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P0AEL3

- FEOA_ECOLI

UniProt

P0AEL3 - FEOA_ECOLI

Protein

Ferrous iron transport protein A

Gene

feoA

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Not known. Involved in Fe2+ ion uptake.

    GO - Molecular functioni

    1. transition metal ion binding Source: InterPro

    GO - Biological processi

    1. cellular response to DNA damage stimulus Source: EcoliWiki
    2. ferrous iron import Source: EcoCyc
    3. iron ion homeostasis Source: UniProtKB-KW

    Keywords - Biological processi

    Ion transport, Iron transport, Transport

    Keywords - Ligandi

    Iron

    Enzyme and pathway databases

    BioCyciEcoCyc:EG12101-MONOMER.
    ECOL316407:JW3371-MONOMER.

    Protein family/group databases

    TCDBi9.A.8.1.1. the ferrous iron uptake (feob) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ferrous iron transport protein A
    Gene namesi
    Name:feoA
    Ordered Locus Names:b3408, JW3371
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG12101. feoA.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7575Ferrous iron transport protein APRO_0000087222Add
    BLAST

    Proteomic databases

    PaxDbiP0AEL3.

    Expressioni

    Gene expression databases

    GenevestigatoriP0AEL3.

    Interactioni

    Protein-protein interaction databases

    IntActiP0AEL3. 4 interactions.
    STRINGi511145.b3408.

    Structurei

    Secondary structure

    1
    75
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi8 – 136
    Beta strandi16 – 183
    Helixi20 – 289
    Beta strandi33 – 4210
    Turni44 – 463
    Beta strandi49 – 524
    Beta strandi57 – 604
    Helixi62 – 676
    Beta strandi68 – 725

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2GCXNMR-A1-73[»]
    2LX9NMR-A1-75[»]
    ProteinModelPortaliP0AEL3.
    SMRiP0AEL3. Positions 1-74.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP0AEL3.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG1918.
    HOGENOMiHOG000053908.
    KOiK04758.
    OMAiKCLENDF.
    OrthoDBiEOG6J48SS.
    PhylomeDBiP0AEL3.

    Family and domain databases

    InterProiIPR007167. Fe-transptr_FeoA.
    IPR008988. Transcriptional_repressor_C.
    [Graphical view]
    PfamiPF04023. FeoA. 1 hit.
    [Graphical view]
    SMARTiSM00899. FeoA. 1 hit.
    [Graphical view]
    SUPFAMiSSF50037. SSF50037. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0AEL3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQYTPDTAWK ITGFSREISP AYRQKLLSLG MLPGSSFNVV RVAPLGDPIH   50
    IETRRVSLVL RKKDLALLEV EAVSC 75
    Length:75
    Mass (Da):8,371
    Last modified:December 20, 2005 - v1
    Checksum:i945AC2E01C24CC92
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X71063 Genomic DNA. Translation: CAA50386.1.
    U18997 Genomic DNA. Translation: AAA58206.1.
    U00096 Genomic DNA. Translation: AAC76433.1.
    AP009048 Genomic DNA. Translation: BAE77883.1.
    PIRiB36932.
    RefSeqiNP_417867.1. NC_000913.3.
    YP_492024.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC76433; AAC76433; b3408.
    BAE77883; BAE77883; BAE77883.
    GeneIDi12932730.
    947909.
    KEGGiecj:Y75_p3768.
    eco:b3408.
    PATRICi32122252. VBIEscCol129921_3503.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X71063 Genomic DNA. Translation: CAA50386.1 .
    U18997 Genomic DNA. Translation: AAA58206.1 .
    U00096 Genomic DNA. Translation: AAC76433.1 .
    AP009048 Genomic DNA. Translation: BAE77883.1 .
    PIRi B36932.
    RefSeqi NP_417867.1. NC_000913.3.
    YP_492024.1. NC_007779.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2GCX NMR - A 1-73 [» ]
    2LX9 NMR - A 1-75 [» ]
    ProteinModelPortali P0AEL3.
    SMRi P0AEL3. Positions 1-74.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P0AEL3. 4 interactions.
    STRINGi 511145.b3408.

    Protein family/group databases

    TCDBi 9.A.8.1.1. the ferrous iron uptake (feob) family.

    Proteomic databases

    PaxDbi P0AEL3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC76433 ; AAC76433 ; b3408 .
    BAE77883 ; BAE77883 ; BAE77883 .
    GeneIDi 12932730.
    947909.
    KEGGi ecj:Y75_p3768.
    eco:b3408.
    PATRICi 32122252. VBIEscCol129921_3503.

    Organism-specific databases

    EchoBASEi EB2025.
    EcoGenei EG12101. feoA.

    Phylogenomic databases

    eggNOGi COG1918.
    HOGENOMi HOG000053908.
    KOi K04758.
    OMAi KCLENDF.
    OrthoDBi EOG6J48SS.
    PhylomeDBi P0AEL3.

    Enzyme and pathway databases

    BioCyci EcoCyc:EG12101-MONOMER.
    ECOL316407:JW3371-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P0AEL3.
    PROi P0AEL3.

    Gene expression databases

    Genevestigatori P0AEL3.

    Family and domain databases

    InterProi IPR007167. Fe-transptr_FeoA.
    IPR008988. Transcriptional_repressor_C.
    [Graphical view ]
    Pfami PF04023. FeoA. 1 hit.
    [Graphical view ]
    SMARTi SM00899. FeoA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50037. SSF50037. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of the ferrous iron uptake system of Escherichia coli."
      Kammler M., Schoen C., Hantke K.
      J. Bacteriol. 175:6212-6219(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: K12.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiFEOA_ECOLI
    AccessioniPrimary (citable) accession number: P0AEL3
    Secondary accession number(s): P33649, Q2M773
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 20, 2005
    Last sequence update: December 20, 2005
    Last modified: July 9, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3