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Protein

Protein ElaB

Gene

elaB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7173-MONOMER.
ECOL316407:JW2261-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ElaB
Gene namesi
Name:elaB
Synonyms:yfbD
Ordered Locus Names:b2266, JW2261
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13185. elaB.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei80 – 9920HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • cytosol Source: EcoCyc
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 101101Protein ElaBPRO_0000086947Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-acetyllysine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

EPDiP0AEH5.
PaxDbiP0AEH5.
PRIDEiP0AEH5.

Expressioni

Inductioni

Maximally expressed between 6 and 12 hours of growth, in early stationary phase.1 Publication

Interactioni

Subunit structurei

Upon overexpression binds to ribosomes.

Protein-protein interaction databases

BioGridi4260520. 7 interactions.
DIPiDIP-47919N.
IntActiP0AEH5. 10 interactions.
MINTiMINT-1311168.
STRINGi511145.b2266.

Structurei

3D structure databases

ProteinModelPortaliP0AEH5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ElaB/YgaM/YqjD family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105TNS. Bacteria.
COG4575. LUCA.
HOGENOMiHOG000256775.
InParanoidiP0AEH5.
KOiK05594.
OMAiEYVHEKP.
OrthoDBiEOG6DNTDK.

Family and domain databases

InterProiIPR010279. DUF883_ElaB.
[Graphical view]
PfamiPF05957. DUF883. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AEH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNQFGDTRI DDDLTLLSET LEEVLRSSGD PADQKYVELK ARAEKALDDV
60 70 80 90 100
KKRVSQASDS YYYRAKQAVY RADDYVHEKP WQGIGVGAAV GLVLGLLLAR

R
Length:101
Mass (Da):11,306
Last modified:December 6, 2005 - v1
Checksum:iB934E815C373CF6F
GO

Sequence cautioni

The sequence Z50849 differs from that shown. Reason: Frameshift at position 73. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z50849 Genomic DNA. No translation available.
U58768 Genomic DNA. Translation: AAB02730.1.
U00096 Genomic DNA. Translation: AAC75326.1.
AP009048 Genomic DNA. Translation: BAA16093.1.
PIRiH64997.
RefSeqiNP_416769.1. NC_000913.3.
WP_000070621.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75326; AAC75326; b2266.
BAA16093; BAA16093; BAA16093.
GeneIDi946751.
KEGGiecj:JW2261.
eco:b2266.
PATRICi32119899. VBIEscCol129921_2359.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z50849 Genomic DNA. No translation available.
U58768 Genomic DNA. Translation: AAB02730.1.
U00096 Genomic DNA. Translation: AAC75326.1.
AP009048 Genomic DNA. Translation: BAA16093.1.
PIRiH64997.
RefSeqiNP_416769.1. NC_000913.3.
WP_000070621.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AEH5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260520. 7 interactions.
DIPiDIP-47919N.
IntActiP0AEH5. 10 interactions.
MINTiMINT-1311168.
STRINGi511145.b2266.

Proteomic databases

EPDiP0AEH5.
PaxDbiP0AEH5.
PRIDEiP0AEH5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75326; AAC75326; b2266.
BAA16093; BAA16093; BAA16093.
GeneIDi946751.
KEGGiecj:JW2261.
eco:b2266.
PATRICi32119899. VBIEscCol129921_2359.

Organism-specific databases

EchoBASEiEB2977.
EcoGeneiEG13185. elaB.

Phylogenomic databases

eggNOGiENOG4105TNS. Bacteria.
COG4575. LUCA.
HOGENOMiHOG000256775.
InParanoidiP0AEH5.
KOiK05594.
OMAiEYVHEKP.
OrthoDBiEOG6DNTDK.

Enzyme and pathway databases

BioCyciEcoCyc:G7173-MONOMER.
ECOL316407:JW2261-MONOMER.

Miscellaneous databases

PROiP0AEH5.

Family and domain databases

InterProiIPR010279. DUF883_ElaB.
[Graphical view]
PfamiPF05957. DUF883. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "An isochorismate hydroxymutase isogene in Escherichia coli."
    Mueller R., Dahm C., Schulte G., Leistner E.
    FEBS Lett. 378:131-134(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.
  2. "Characterization of the ela locus from Escherichia coli."
    Huisman G.W.
    Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  3. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  5. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  6. Rudd K.E.
    Unpublished observations (MAR-1996)
    Cited for: IDENTIFICATION.
  7. "Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli."
    Zhang J., Sprung R., Pei J., Tan X., Kim S., Zhu H., Liu C.F., Grishin N.V., Zhao Y.
    Mol. Cell. Proteomics 8:215-225(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-35, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: K12 / JW1106 and K12 / MG1655 / ATCC 47076.
  8. "YqjD is an inner membrane protein associated with stationary-phase ribosomes in Escherichia coli."
    Yoshida H., Maki Y., Furuike S., Sakai A., Ueta M., Wada A.
    J. Bacteriol. 194:4178-4183(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: RIBOSOME-BINDING, INDUCTION.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiELAB_ECOLI
AccessioniPrimary (citable) accession number: P0AEH5
Secondary accession number(s): P52084, Q47010
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: March 16, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.