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P0AEC0 (YOAE_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UPF0053 inner membrane protein YoaE
Gene names
Name:yoaE
Ordered Locus Names:b1816, JW1805
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length518 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the UPF0053 family.

Contains 2 CBS domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 518518UPF0053 inner membrane protein YoaE
PRO_0000088359

Regions

Topological domain1 – 1313Cytoplasmic Potential
Transmembrane14 – 3421Helical; Potential
Topological domain35 – 4814Periplasmic Potential
Transmembrane49 – 6921Helical; Potential
Topological domain70 – 789Cytoplasmic Potential
Transmembrane79 – 9921Helical; Potential
Topological domain100 – 12425Periplasmic Potential
Transmembrane125 – 14521Helical; Potential
Topological domain146 – 1494Cytoplasmic Potential
Transmembrane150 – 17021Helical; Potential
Topological domain171 – 18414Periplasmic Potential
Transmembrane185 – 20521Helical; Potential
Topological domain2061Cytoplasmic Potential
Transmembrane207 – 22721Helical; Potential
Topological domain228 – 354127Periplasmic Potential
Transmembrane355 – 37521Helical; Potential
Topological domain376 – 518143Cytoplasmic Potential
Domain304 – 36360CBS 1
Domain367 – 42761CBS 2

Sequences

Sequence LengthMass (Da)Tools
P0AEC0 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 90DF7C9A092F1ECC

FASTA51856,528
        10         20         30         40         50         60 
MEFLMDPSIW AGLLTLVVLE IVLGIDNLVF IAILADKLPP KQRDKARLLG LSLALIMRLG 

        70         80         90        100        110        120 
LLSLISWMVT LTKPLFTVMD FSFSGRDLIM LFGGIFLLFK ATTELHERLE NRDHDSGHGK 

       130        140        150        160        170        180 
GYASFWVVVT QIVILDAVFS LDAVITAVGM VNHLPVMMAA VVIAMAVMLL ASKPLTRFVN 

       190        200        210        220        230        240 
QHPTVVVLCL SFLLMIGLSL VAEGFGFHIP KGYLYAAIGF SIIIEVFNQI ARRNFIRHQS 

       250        260        270        280        290        300 
TLPLRARTAD AILRLMGGKR QANVQHDADN PMPMPIPEGA FAEEERYMIN GVLTLASRSL 

       310        320        330        340        350        360 
RGIMTPRGEI SWVDANLGVD EIREQLLSSP HSLFPVCRGE LDEIIGIVRA KELLVALEEG 

       370        380        390        400        410        420 
VDVAAIASAS PAIIVPETLD PINLLGVLRR ARGSFVIVTN EFGVVQGLVT PLDVLEAIAG 

       430        440        450        460        470        480 
EFPDADETPE IITDGDGWLV KGGTDLHALQ QALDVEHLAD DDDIATVAGL VISANGHIPR 

       490        500        510 
VGDVIDVGPL HITIIEANDY RVDLVRIVKE QPAHDEDE

« Hide

References

[1]"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map."
Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. expand/collapse author list , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:379-392(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U00096 Genomic DNA. Translation: AAC74886.1.
AP009048 Genomic DNA. Translation: BAA15623.1.
PIRH64942.
RefSeqNP_416330.1. NC_000913.2.
YP_490077.1. NC_007779.1.

3D structure databases

ProteinModelPortalP0AEC0.
SMRP0AEC0. Positions 280-429.
ModBaseSearch...

Protein-protein interaction databases

STRING511145.b1816.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC74886; AAC74886; b1816.
BAA15623; BAA15623; BAA15623.
GeneID12931353.
946335.
KEGGecj:Y75_p1791.
eco:b1816.
PATRIC32118951. VBIEscCol129921_1893.

Organism-specific databases

EchoBASEEB3290.
EcoGeneEG13517. yoaE.

Phylogenomic databases

eggNOGCOG1253.
HOGENOMHOG000279402.
OMARHPTIVI.
ProtClustDBCLSK866497.

Enzyme and pathway databases

BioCycEcoCyc:G6997-MONOMER.
ECOL316407:JW1805-MONOMER.

Gene expression databases

GenevestigatorP0AEC0.

Family and domain databases

Gene3D3.30.465.10. 1 hit.
InterProIPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR000644. Cysta_beta_synth_core.
IPR005496. Integral_membrane_TerC.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamPF00571. CBS. 1 hit.
PF03471. CorC_HlyC. 1 hit.
PF03741. TerC. 1 hit.
[Graphical view]
SMARTSM01091. CorC_HlyC. 1 hit.
[Graphical view]
PROSITEPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYOAE_ECOLI
AccessionPrimary (citable) accession number: P0AEC0
Secondary accession number(s): P76262
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents