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Protein

Protein CreA

Gene

creA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11217-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein CreA
Alternative name(s):
Catabolite regulation protein A
Gene namesi
Name:creA
Synonyms:yjjD
Ordered Locus Names:b4397, JW4360
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11217 creA

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

Pathology & Biotechi

Disruption phenotypei

No crucial effects on activation of cre regulon gene expression during aerobic growth on glucose or pyruvate minimal medium or during anaerobic growth on glucose minimal medium.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000007933922 – 157Protein CreAAdd BLAST136

Proteomic databases

PaxDbiP0AE91
PRIDEiP0AE91

Interactioni

Protein-protein interaction databases

BioGridi4259351, 10 interactors
IntActiP0AE91, 1 interactor
STRINGi316385.ECDH10B_4555

Structurei

3D structure databases

ProteinModelPortaliP0AE91
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108RH0 Bacteria
COG3045 LUCA
HOGENOMiHOG000257967
InParanoidiP0AE91
KOiK05805
OMAiQGVTCYV
PhylomeDBiP0AE91

Family and domain databases

InterProiView protein in InterPro
IPR010292 Uncharacterised_CreA
PANTHERiPTHR37952 PTHR37952, 1 hit
PfamiView protein in Pfam
PF05981 CreA, 1 hit
PIRSFiPIRSF003174 CreA, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AE91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYKHLILSL SLIMLGPLAH AEEIGSVDTV FKMIGPDHKI VVEAFDDPDV
60 70 80 90 100
KNVTCYVSRA KTGGIKGGLG LAEDTSDAAI SCQQVGPIEL SDRIKNGKAQ
110 120 130 140 150
GEVVFKKRTS LVFKSLQVVR FYDAKRNALA YLAYSDKVVE GSPKNAISAV

PVMPWRQ
Length:157
Mass (Da):17,108
Last modified:August 1, 1988 - v1
Checksum:iEC33001A09DC680F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M13608 Genomic DNA Translation: AAA24373.1
U14003 Genomic DNA Translation: AAA97293.1
U00096 Genomic DNA Translation: AAC77350.1
AP009048 Genomic DNA Translation: BAE78386.1
M97495 Genomic DNA Translation: AAA24568.1
PIRiA25038 QQECF1
RefSeqiNP_418814.1, NC_000913.3
WP_000875487.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77350; AAC77350; b4397
BAE78386; BAE78386; BAE78386
GeneIDi948920
KEGGiecj:JW4360
eco:b4397
PATRICifig|511145.12.peg.4546

Similar proteinsi

Entry informationi

Entry nameiCREA_ECOLI
AccessioniPrimary (citable) accession number: P0AE91
Secondary accession number(s): P08367, Q2M5S0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: March 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health