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P0AE91

- CREA_ECOLI

UniProt

P0AE91 - CREA_ECOLI

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Protein

Protein CreA

Gene
creA, yjjD, b4397, JW4360
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11217-MONOMER.
ECOL316407:JW4360-MONOMER.
RETL1328306-WGS:GSTH-2875-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein CreA
Alternative name(s):
Catabolite regulation protein A
Gene namesi
Name:creA
Synonyms:yjjD
Ordered Locus Names:b4397, JW4360
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG11217. creA.

Pathology & Biotechi

Disruption phenotypei

No crucial effects on activation of cre regulon gene expression during aerobic growth on glucose or pyruvate minimal medium or during anaerobic growth on glucose minimal medium.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121 Reviewed predictionAdd
BLAST
Chaini22 – 157136Protein CreAPRO_0000079339Add
BLAST

Proteomic databases

PaxDbiP0AE91.
PRIDEiP0AE91.

Expressioni

Gene expression databases

GenevestigatoriP0AE91.

Interactioni

Protein-protein interaction databases

IntActiP0AE91. 1 interaction.
STRINGi511145.b4397.

Structurei

3D structure databases

ProteinModelPortaliP0AE91.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG3045.
HOGENOMiHOG000257967.
KOiK05805.
OMAiVAGVTCY.
OrthoDBiEOG6MD95K.
PhylomeDBiP0AE91.

Family and domain databases

InterProiIPR010292. Uncharacterised_CreA.
[Graphical view]
PfamiPF05981. CreA. 1 hit.
[Graphical view]
PIRSFiPIRSF003174. CreA. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AE91-1 [UniParc]FASTAAdd to Basket

« Hide

MKYKHLILSL SLIMLGPLAH AEEIGSVDTV FKMIGPDHKI VVEAFDDPDV    50
KNVTCYVSRA KTGGIKGGLG LAEDTSDAAI SCQQVGPIEL SDRIKNGKAQ 100
GEVVFKKRTS LVFKSLQVVR FYDAKRNALA YLAYSDKVVE GSPKNAISAV 150
PVMPWRQ 157
Length:157
Mass (Da):17,108
Last modified:August 1, 1988 - v1
Checksum:iEC33001A09DC680F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M13608 Genomic DNA. Translation: AAA24373.1.
U14003 Genomic DNA. Translation: AAA97293.1.
U00096 Genomic DNA. Translation: AAC77350.1.
AP009048 Genomic DNA. Translation: BAE78386.1.
M97495 Genomic DNA. Translation: AAA24568.1.
PIRiA25038. QQECF1.
RefSeqiNP_418814.1. NC_000913.3.
YP_492527.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC77350; AAC77350; b4397.
BAE78386; BAE78386; BAE78386.
GeneIDi12930357.
948920.
KEGGiecj:Y75_p4281.
eco:b4397.
PATRICi32124412. VBIEscCol129921_4546.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M13608 Genomic DNA. Translation: AAA24373.1 .
U14003 Genomic DNA. Translation: AAA97293.1 .
U00096 Genomic DNA. Translation: AAC77350.1 .
AP009048 Genomic DNA. Translation: BAE78386.1 .
M97495 Genomic DNA. Translation: AAA24568.1 .
PIRi A25038. QQECF1.
RefSeqi NP_418814.1. NC_000913.3.
YP_492527.1. NC_007779.1.

3D structure databases

ProteinModelPortali P0AE91.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P0AE91. 1 interaction.
STRINGi 511145.b4397.

Proteomic databases

PaxDbi P0AE91.
PRIDEi P0AE91.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC77350 ; AAC77350 ; b4397 .
BAE78386 ; BAE78386 ; BAE78386 .
GeneIDi 12930357.
948920.
KEGGi ecj:Y75_p4281.
eco:b4397.
PATRICi 32124412. VBIEscCol129921_4546.

Organism-specific databases

EchoBASEi EB1200.
EcoGenei EG11217. creA.

Phylogenomic databases

eggNOGi COG3045.
HOGENOMi HOG000257967.
KOi K05805.
OMAi VAGVTCY.
OrthoDBi EOG6MD95K.
PhylomeDBi P0AE91.

Enzyme and pathway databases

BioCyci EcoCyc:EG11217-MONOMER.
ECOL316407:JW4360-MONOMER.
RETL1328306-WGS:GSTH-2875-MONOMER.

Miscellaneous databases

PROi P0AE91.

Gene expression databases

Genevestigatori P0AE91.

Family and domain databases

InterProi IPR010292. Uncharacterised_CreA.
[Graphical view ]
Pfami PF05981. CreA. 1 hit.
[Graphical view ]
PIRSFi PIRSF003174. CreA. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of the phoM region of Escherichia coli: four open reading frames may constitute an operon."
    Amemura M., Makino K., Shinagawa H., Nakata A.
    J. Bacteriol. 168:294-302(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
    Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
    Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "A novel binding protein of the origin of the Escherichia coli chromosome."
    Skarstad K., Thoeny B., Hwang D.S., Kornberg A.
    J. Biol. Chem. 268:5365-5370(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  6. "Defining the growth conditions and promoter-proximal DNA sequences required for activation of gene expression by CreBC in Escherichia coli."
    Cariss S.J., Tayler A.E., Avison M.B.
    J. Bacteriol. 190:3930-3939(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.
    Strain: K12 / DH5-alpha.

Entry informationi

Entry nameiCREA_ECOLI
AccessioniPrimary (citable) accession number: P0AE91
Secondary accession number(s): P08367, Q2M5S0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: July 9, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

External Data

Dasty 3

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