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P0AE91 (CREA_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein CreA
Alternative name(s):
Catabolite regulation protein A
Gene names
Name:creA
Synonyms:yjjD
Ordered Locus Names:b4397, JW4360
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length157 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existencePredicted

General annotation (Comments)

Disruption phenotype

No crucial effects on activation of cre regulon gene expression during aerobic growth on glucose or pyruvate minimal medium or during anaerobic growth on glucose minimal medium. Ref.6

Ontologies

Keywords
   DomainSignal
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 157136Protein CreA
PRO_0000079339

Sequences

Sequence LengthMass (Da)Tools
P0AE91 [UniParc].

Last modified August 1, 1988. Version 1.
Checksum: EC33001A09DC680F

FASTA15717,108
        10         20         30         40         50         60 
MKYKHLILSL SLIMLGPLAH AEEIGSVDTV FKMIGPDHKI VVEAFDDPDV KNVTCYVSRA 

        70         80         90        100        110        120 
KTGGIKGGLG LAEDTSDAAI SCQQVGPIEL SDRIKNGKAQ GEVVFKKRTS LVFKSLQVVR 

       130        140        150 
FYDAKRNALA YLAYSDKVVE GSPKNAISAV PVMPWRQ 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence of the phoM region of Escherichia coli: four open reading frames may constitute an operon."
Amemura M., Makino K., Shinagawa H., Nakata A.
J. Bacteriol. 168:294-302(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"A novel binding protein of the origin of the Escherichia coli chromosome."
Skarstad K., Thoeny B., Hwang D.S., Kornberg A.
J. Biol. Chem. 268:5365-5370(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28.
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[6]"Defining the growth conditions and promoter-proximal DNA sequences required for activation of gene expression by CreBC in Escherichia coli."
Cariss S.J., Tayler A.E., Avison M.B.
J. Bacteriol. 190:3930-3939(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: DISRUPTION PHENOTYPE.
Strain: K12 / DH5-alpha.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M13608 Genomic DNA. Translation: AAA24373.1.
U14003 Genomic DNA. Translation: AAA97293.1.
U00096 Genomic DNA. Translation: AAC77350.1.
AP009048 Genomic DNA. Translation: BAE78386.1.
M97495 Genomic DNA. Translation: AAA24568.1.
PIRQQECF1. A25038.
RefSeqNP_418814.1. NC_000913.3.
YP_492527.1. NC_007779.1.

3D structure databases

ProteinModelPortalP0AE91.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP0AE91. 1 interaction.
STRING511145.b4397.

Proteomic databases

PaxDbP0AE91.
PRIDEP0AE91.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC77350; AAC77350; b4397.
BAE78386; BAE78386; BAE78386.
GeneID12930357.
948920.
KEGGecj:Y75_p4281.
eco:b4397.
PATRIC32124412. VBIEscCol129921_4546.

Organism-specific databases

EchoBASEEB1200.
EcoGeneEG11217. creA.

Phylogenomic databases

eggNOGCOG3045.
HOGENOMHOG000257967.
KOK05805.
OMAVAGVTCY.
OrthoDBEOG6MD95K.
PhylomeDBP0AE91.

Enzyme and pathway databases

BioCycEcoCyc:EG11217-MONOMER.
ECOL316407:JW4360-MONOMER.
RETL1328306-WGS:GSTH-2875-MONOMER.

Gene expression databases

GenevestigatorP0AE91.

Family and domain databases

InterProIPR010292. Uncharacterised_CreA.
[Graphical view]
PfamPF05981. CreA. 1 hit.
[Graphical view]
PIRSFPIRSF003174. CreA. 1 hit.
ProtoNetSearch...

Other

PROP0AE91.

Entry information

Entry nameCREA_ECOLI
AccessionPrimary (citable) accession number: P0AE91
Secondary accession number(s): P08367, Q2M5S0
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: July 9, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene