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P0AE91

- CREA_ECOLI

UniProt

P0AE91 - CREA_ECOLI

Protein

Protein CreA

Gene

creA

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Enzyme and pathway databases

    BioCyciEcoCyc:EG11217-MONOMER.
    ECOL316407:JW4360-MONOMER.
    RETL1328306-WGS:GSTH-2875-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein CreA
    Alternative name(s):
    Catabolite regulation protein A
    Gene namesi
    Name:creA
    Synonyms:yjjD
    Ordered Locus Names:b4397, JW4360
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG11217. creA.

    Pathology & Biotechi

    Disruption phenotypei

    No crucial effects on activation of cre regulon gene expression during aerobic growth on glucose or pyruvate minimal medium or during anaerobic growth on glucose minimal medium.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2121Sequence AnalysisAdd
    BLAST
    Chaini22 – 157136Protein CreAPRO_0000079339Add
    BLAST

    Proteomic databases

    PaxDbiP0AE91.
    PRIDEiP0AE91.

    Expressioni

    Gene expression databases

    GenevestigatoriP0AE91.

    Interactioni

    Protein-protein interaction databases

    IntActiP0AE91. 1 interaction.
    STRINGi511145.b4397.

    Structurei

    3D structure databases

    ProteinModelPortaliP0AE91.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG3045.
    HOGENOMiHOG000257967.
    KOiK05805.
    OMAiVAGVTCY.
    OrthoDBiEOG6MD95K.
    PhylomeDBiP0AE91.

    Family and domain databases

    InterProiIPR010292. Uncharacterised_CreA.
    [Graphical view]
    PfamiPF05981. CreA. 1 hit.
    [Graphical view]
    PIRSFiPIRSF003174. CreA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P0AE91-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKYKHLILSL SLIMLGPLAH AEEIGSVDTV FKMIGPDHKI VVEAFDDPDV    50
    KNVTCYVSRA KTGGIKGGLG LAEDTSDAAI SCQQVGPIEL SDRIKNGKAQ 100
    GEVVFKKRTS LVFKSLQVVR FYDAKRNALA YLAYSDKVVE GSPKNAISAV 150
    PVMPWRQ 157
    Length:157
    Mass (Da):17,108
    Last modified:August 1, 1988 - v1
    Checksum:iEC33001A09DC680F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M13608 Genomic DNA. Translation: AAA24373.1.
    U14003 Genomic DNA. Translation: AAA97293.1.
    U00096 Genomic DNA. Translation: AAC77350.1.
    AP009048 Genomic DNA. Translation: BAE78386.1.
    M97495 Genomic DNA. Translation: AAA24568.1.
    PIRiA25038. QQECF1.
    RefSeqiNP_418814.1. NC_000913.3.
    YP_492527.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC77350; AAC77350; b4397.
    BAE78386; BAE78386; BAE78386.
    GeneIDi12930357.
    948920.
    KEGGiecj:Y75_p4281.
    eco:b4397.
    PATRICi32124412. VBIEscCol129921_4546.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M13608 Genomic DNA. Translation: AAA24373.1 .
    U14003 Genomic DNA. Translation: AAA97293.1 .
    U00096 Genomic DNA. Translation: AAC77350.1 .
    AP009048 Genomic DNA. Translation: BAE78386.1 .
    M97495 Genomic DNA. Translation: AAA24568.1 .
    PIRi A25038. QQECF1.
    RefSeqi NP_418814.1. NC_000913.3.
    YP_492527.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P0AE91.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P0AE91. 1 interaction.
    STRINGi 511145.b4397.

    Proteomic databases

    PaxDbi P0AE91.
    PRIDEi P0AE91.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC77350 ; AAC77350 ; b4397 .
    BAE78386 ; BAE78386 ; BAE78386 .
    GeneIDi 12930357.
    948920.
    KEGGi ecj:Y75_p4281.
    eco:b4397.
    PATRICi 32124412. VBIEscCol129921_4546.

    Organism-specific databases

    EchoBASEi EB1200.
    EcoGenei EG11217. creA.

    Phylogenomic databases

    eggNOGi COG3045.
    HOGENOMi HOG000257967.
    KOi K05805.
    OMAi VAGVTCY.
    OrthoDBi EOG6MD95K.
    PhylomeDBi P0AE91.

    Enzyme and pathway databases

    BioCyci EcoCyc:EG11217-MONOMER.
    ECOL316407:JW4360-MONOMER.
    RETL1328306-WGS:GSTH-2875-MONOMER.

    Miscellaneous databases

    PROi P0AE91.

    Gene expression databases

    Genevestigatori P0AE91.

    Family and domain databases

    InterProi IPR010292. Uncharacterised_CreA.
    [Graphical view ]
    Pfami PF05981. CreA. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF003174. CreA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the phoM region of Escherichia coli: four open reading frames may constitute an operon."
      Amemura M., Makino K., Shinagawa H., Nakata A.
      J. Bacteriol. 168:294-302(1986) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
      Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
      Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    5. "A novel binding protein of the origin of the Escherichia coli chromosome."
      Skarstad K., Thoeny B., Hwang D.S., Kornberg A.
      J. Biol. Chem. 268:5365-5370(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28.
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    6. "Defining the growth conditions and promoter-proximal DNA sequences required for activation of gene expression by CreBC in Escherichia coli."
      Cariss S.J., Tayler A.E., Avison M.B.
      J. Bacteriol. 190:3930-3939(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISRUPTION PHENOTYPE.
      Strain: K12 / DH5-alpha.

    Entry informationi

    Entry nameiCREA_ECOLI
    AccessioniPrimary (citable) accession number: P0AE91
    Secondary accession number(s): P08367, Q2M5S0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1988
    Last sequence update: August 1, 1988
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene

    External Data

    Dasty 3