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Protein

Magnesium and cobalt efflux protein CorC

Gene

corC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role in the transport of magnesium and cobalt ions.By similarity

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandCobalt, Magnesium

Enzyme and pathway databases

BioCyciEcoCyc:G6361-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Magnesium and cobalt efflux protein CorC
Gene namesi
Name:corC
Synonyms:ybeX
Ordered Locus Names:b0658, JW0655
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13654 corC

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000883451 – 292Magnesium and cobalt efflux protein CorCAdd BLAST292

Proteomic databases

PaxDbiP0AE78
PRIDEiP0AE78

Interactioni

Protein-protein interaction databases

BioGridi4260830, 549 interactors
DIPiDIP-35960N
IntActiP0AE78, 9 interactors
STRINGi316385.ECDH10B_0727

Structurei

Secondary structure

1292
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi52 – 66Combined sources15
Helixi69 – 71Combined sources3
Turni76 – 78Combined sources3
Beta strandi82 – 86Combined sources5
Helixi88 – 98Combined sources11
Beta strandi101 – 106Combined sources6
Beta strandi108 – 118Combined sources11
Helixi119 – 122Combined sources4
Turni123 – 126Combined sources4
Beta strandi144 – 146Combined sources3
Helixi151 – 161Combined sources11
Beta strandi165 – 169Combined sources5
Beta strandi175 – 180Combined sources6
Helixi181 – 189Combined sources9
Beta strandi206 – 208Combined sources3
Beta strandi211 – 215Combined sources5
Helixi220 – 227Combined sources8
Helixi239 – 247Combined sources9
Beta strandi256 – 261Combined sources6
Beta strandi263 – 269Combined sources7
Beta strandi274 – 280Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4HG0X-ray3.10A1-292[»]
ProteinModelPortaliP0AE78
SMRiP0AE78
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 133CBS 1PROSITE-ProRule annotationAdd BLAST61
Domaini135 – 195CBS 2PROSITE-ProRule annotationAdd BLAST61

Sequence similaritiesi

Belongs to the UPF0053 family.Curated

Keywords - Domaini

CBS domain, Repeat

Phylogenomic databases

eggNOGiENOG4108JU5 Bacteria
COG4535 LUCA
HOGENOMiHOG000062294
InParanoidiP0AE78
KOiK06189
OMAiQMISIKA
PhylomeDBiP0AE78

Family and domain databases

InterProiView protein in InterPro
IPR000644 CBS_dom
IPR036318 FAD-bd_2-like_sf
IPR005170 Transptr-assoc_dom
PfamiView protein in Pfam
PF00571 CBS, 2 hits
PF03471 CorC_HlyC, 1 hit
SMARTiView protein in SMART
SM00116 CBS, 2 hits
SM01091 CorC_HlyC, 1 hit
SUPFAMiSSF56176 SSF56176, 1 hit
PROSITEiView protein in PROSITE
PS51371 CBS, 2 hits

Sequencei

Sequence statusi: Complete.

P0AE78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDDNSHSSD TISNKKGFFS LLLSQLFHGE PKNRDELLAL IRDSGQNDLI
60 70 80 90 100
DEDTRDMLEG VMDIADQRVR DIMIPRSQMI TLKRNQTLDE CLDVIIESAH
110 120 130 140 150
SRFPVISEDK DHIEGILMAK DLLPFMRSDA EAFSMDKVLR QAVVVPESKR
160 170 180 190 200
VDRMLKEFRS QRYHMAIVID EFGGVSGLVT IEDILELIVG EIEDEYDEED
210 220 230 240 250
DIDFRQLSRH TWTVRALASI EDFNEAFGTH FSDEEVDTIG GLVMQAFGHL
260 270 280 290
PARGETIDID GYQFKVAMAD SRRIIQVHVK IPDDSPQPKL DE
Length:292
Mass (Da):33,298
Last modified:December 6, 2005 - v1
Checksum:i7350B8B475485B32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA Translation: AAB40860.1
U00096 Genomic DNA Translation: AAC73759.1
AP009048 Genomic DNA Translation: BAA35309.2
PIRiH64800
RefSeqiNP_415191.1, NC_000913.3
WP_001278605.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73759; AAC73759; b0658
BAA35309; BAA35309; BAA35309
GeneIDi946417
KEGGiecj:JW0655
eco:b0658
PATRICifig|1411691.4.peg.1610

Similar proteinsi

Entry informationi

Entry nameiCORC_ECOLI
AccessioniPrimary (citable) accession number: P0AE78
Secondary accession number(s): P77392
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health