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P0AE78 (CORC_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Magnesium and cobalt efflux protein CorC
Gene names
Name:corC
Synonyms:ybeX
Ordered Locus Names:b0658, JW0655
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Plays a role in the transport of magnesium and cobalt ions By similarity.

Sequence similarities

Belongs to the UPF0053 family.

Contains 2 CBS domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 292292Magnesium and cobalt efflux protein CorC
PRO_0000088345

Regions

Domain73 – 13361CBS 1
Domain135 – 19561CBS 2

Secondary structure

........................................ 292
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P0AE78 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 7350B8B475485B32

FASTA29233,298
        10         20         30         40         50         60 
MSDDNSHSSD TISNKKGFFS LLLSQLFHGE PKNRDELLAL IRDSGQNDLI DEDTRDMLEG 

        70         80         90        100        110        120 
VMDIADQRVR DIMIPRSQMI TLKRNQTLDE CLDVIIESAH SRFPVISEDK DHIEGILMAK 

       130        140        150        160        170        180 
DLLPFMRSDA EAFSMDKVLR QAVVVPESKR VDRMLKEFRS QRYHMAIVID EFGGVSGLVT 

       190        200        210        220        230        240 
IEDILELIVG EIEDEYDEED DIDFRQLSRH TWTVRALASI EDFNEAFGTH FSDEEVDTIG 

       250        260        270        280        290 
GLVMQAFGHL PARGETIDID GYQFKVAMAD SRRIIQVHVK IPDDSPQPKL DE 

« Hide

References

[1]"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map."
Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. expand/collapse author list , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T.
DNA Res. 3:137-155(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"Sequence of minutes 4-25 of Escherichia coli."
Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U82598 Genomic DNA. Translation: AAB40860.1.
U00096 Genomic DNA. Translation: AAC73759.1.
AP009048 Genomic DNA. Translation: BAA35309.2.
PIRH64800.
RefSeqNP_415191.1. NC_000913.3.
YP_488949.1. NC_007779.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4HG0X-ray3.10A1-292[»]
ProteinModelPortalP0AE78.
SMRP0AE78. Positions 51-282.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-35960N.
IntActP0AE78. 8 interactions.
STRING511145.b0658.

Proteomic databases

PaxDbP0AE78.
PRIDEP0AE78.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC73759; AAC73759; b0658.
BAA35309; BAA35309; BAA35309.
GeneID12931836.
946417.
KEGGecj:Y75_p0648.
eco:b0658.
PATRIC32116505. VBIEscCol129921_0692.

Organism-specific databases

EchoBASEEB3418.
EcoGeneEG13654. corC.

Phylogenomic databases

eggNOGCOG4535.
HOGENOMHOG000062294.
KOK06189.
OMAGDDAFSP.
OrthoDBEOG60W7V4.
PhylomeDBP0AE78.
ProtClustDBPRK15094.

Enzyme and pathway databases

BioCycEcoCyc:G6361-MONOMER.
ECOL316407:JW0655-MONOMER.

Gene expression databases

GenevestigatorP0AE78.

Family and domain databases

Gene3D3.30.465.10. 1 hit.
InterProIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamPF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]
SMARTSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMSSF56176. SSF56176. 1 hit.
PROSITEPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

PROP0AE78.

Entry information

Entry nameCORC_ECOLI
AccessionPrimary (citable) accession number: P0AE78
Secondary accession number(s): P77392
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: April 16, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene