Magnesium and cobalt efflux protein CorC - Escherichia coli (strain K12)

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P0AE78 (CORC_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 57. History...

Clusters with 100%, 90%, 50% identity |

Documents (4) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Magnesium and cobalt efflux protein CorC

Gene names

Name:	corC
Synonyms:	ybeX
Ordered Locus Names:	b0658, JW0655

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function

Plays a role in the transport of magnesium and cobalt ions By similarity.

Sequence similarities

Belongs to the UPF0053 family.

Contains 2 CBS domains.

Ontologies

Keywords
Biological process	Transport
Domain	CBS domain Repeat
Ligand	Cobalt Magnesium
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 292

292

Magnesium and cobalt efflux protein CorC

PRO_0000088345

Regions

Domain

73 – 133

CBS 1

Domain

135 – 195

CBS 2

Secondary structure

292

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

P0AE78 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 7350B8B475485B32
Show »

FASTA

292

33,298

        10         20         30         40         50         60 
MSDDNSHSSD TISNKKGFFS LLLSQLFHGE PKNRDELLAL IRDSGQNDLI DEDTRDMLEG 

        70         80         90        100        110        120 
VMDIADQRVR DIMIPRSQMI TLKRNQTLDE CLDVIIESAH SRFPVISEDK DHIEGILMAK 

       130        140        150        160        170        180 
DLLPFMRSDA EAFSMDKVLR QAVVVPESKR VDRMLKEFRS QRYHMAIVID EFGGVSGLVT 

       190        200        210        220        230        240 
IEDILELIVG EIEDEYDEED DIDFRQLSRH TWTVRALASI EDFNEAFGTH FSDEEVDTIG 

       250        260        270        280        290 
GLVMQAFGHL PARGETIDID GYQFKVAMAD SRRIIQVHVK IPDDSPQPKL DE

« Hide

References

[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. Horiuchi T. DNA Res. 3:137-155(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"Sequence of minutes 4-25 of Escherichia coli." Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W. Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U82598 Genomic DNA. Translation: AAB40860.1.
U00096 Genomic DNA. Translation: AAC73759.1.
AP009048 Genomic DNA. Translation: BAA35309.2.

PIR

H64800.

RefSeq

NP_415191.1. NC_000913.2.
YP_488949.1. NC_007779.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4HG0	X-ray	3.10	A	1-292	[»]

ProteinModelPortal

P0AE78.

SMR

P0AE78. Positions 35-191, 212-274.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-35960N.

IntAct

P0AE78. 8 interactions.

STRING

511145.b0658.

Proteomic databases

PaxDb

P0AE78.

PRIDE

P0AE78.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAC73759; AAC73759; b0658.
BAA35309; BAA35309; BAA35309.

GeneID

12931836.
946417.

KEGG

ecj:Y75_p0648.
eco:b0658.

PATRIC

32116505. VBIEscCol129921_0692.

Organism-specific databases

EchoBASE

EB3418.

EcoGene

EG13654. corC.

Phylogenomic databases

eggNOG

COG4535.

HOGENOM

HOG000062294.

K06189.

OMA

PFFIPET.

ProtClustDB

PRK15094.

Enzyme and pathway databases

BioCyc

EcoCyc:G6361-MONOMER.
ECOL316407:JW0655-MONOMER.

Gene expression databases

Genevestigator

P0AE78.

Family and domain databases

Gene3D

3.30.465.10. 1 hit.

InterPro

IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR000644. Cysta_beta_synth_core.
IPR005170. Transptr-assoc_dom.
[Graphical view]

Pfam

PF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]

SMART

SM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]

PROSITE

PS51371. CBS. 2 hits.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

CORC_ECOLI

Accession

Primary (citable) accession number: P0AE78
Secondary accession number(s): P77392

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Secondary structure

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents